(Q36312242)

13 August 2017

Matrix compliance regulates Rac1b localization, NADPH oxidase assembly, and epithelial-mesenchymal transition (English)

1 reference

13 August 2017

KangAe Lee

1

1 reference

13 August 2017

Qike K Chen

2

1 reference

13 August 2017

Cecillia Lui

3

1 reference

13 August 2017

Magdalena A Cichon

4

1 reference

13 August 2017

Derek C Radisky

5

1 reference

13 August 2017

Celeste M Nelson

6

1 reference

13 August 2017

23 August 2012

1 reference

Molecular Biology of the Cell

13 August 2017

1 reference

13 August 2017

23

1 reference

13 August 2017

20

1 reference

13 August 2017

4097-4108

1 reference

describes a project that uses

13 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3469523/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Matrix compliance and RhoA direct the differentiation of mammary progenitor cells

30 September 2017

1 reference

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In situ force mapping of mammary gland transformation

30 September 2017

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A hitchhiker's guide to mechanobiology

30 September 2017

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The ins and outs of the epithelial to mesenchymal transition in health and disease

30 September 2017

1 reference

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Twist2 contributes to breast cancer progression by promoting an epithelial-mesenchymal transition and cancer stem-like cell self-renewal

30 September 2017

1 reference

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Mammary gland reprogramming: metalloproteinases couple form with function

30 September 2017

1 reference

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Integrins and extracellular matrix in mechanotransduction

30 September 2017

1 reference

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Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression

30 September 2017

1 reference

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The 19-amino acid insertion in the tumor-associated splice isoform Rac1b confers specific binding to p120 catenin

30 September 2017

1 reference

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Matrix crosslinking forces tumor progression by enhancing integrin signaling

30 September 2017

1 reference

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Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease.

30 September 2017

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The basics of epithelial-mesenchymal transition

30 September 2017

1 reference

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Mechanosensing machinery for cells under low substratum rigidity.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Laminin and biomimetic extracellular elasticity enhance functional differentiation in mammary epithelia

30 September 2017

1 reference

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B-Raf(V600E) cooperates with alternative spliced Rac1b to sustain colorectal cancer cell survival

30 September 2017

1 reference

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Change in cell shape is required for matrix metalloproteinase-induced epithelial-mesenchymal transition of mammary epithelial cells

30 September 2017

1 reference

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Rac1 accumulates in the nucleus during the G2 phase of the cell cycle and promotes cell division

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Collagen density promotes mammary tumor initiation and progression

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Statins in tumor suppression

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Matrix elasticity directs stem cell lineage specification

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Phosphoinositide-3 kinase-Rac1-c-Jun NH2-terminal kinase signaling mediates collagen I-induced cell scattering and up-regulation of N-cadherin expression in mouse mammary epithelial cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Regulation of NADPH oxidases: the role of Rac proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

ILK, PINCH and parvin: the tIPP of integrin signalling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Substrate rigidity regulates the formation and maintenance of tissues

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Integrin-dependent actomyosin contraction regulates epithelial cell scattering.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Tensional homeostasis and the malignant phenotype

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Phospho-caveolin-1 mediates integrin-regulated membrane domain internalization.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Rac1b, a tumor associated, constitutively active Rac1 splice variant, promotes cellular transformation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Aberrant expression of the transcription factors snail and slug alters the response to genotoxic stress

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Cell adhesion receptors, tyrosine kinases and actin modulators: a complex three-way circuitry.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Vascular endothelial-cadherin regulates cytoskeletal tension, cell spreading, and focal adhesions by stimulating RhoA.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Integrins regulate Rac targeting by internalization of membrane domains

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Substrate compliance versus ligand density in cell on gel responses

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Alternative splicing of Rac1 generates Rac1b, a self-activating GTPase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Site-specific inductive and inhibitory activities of MMP-2 and MMP-3 orchestrate mammary gland branching morphogenesis.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Evidence that fibroblasts derive from epithelium during tissue fibrosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Integrins regulate GTP-Rac localized effector interactions through dissociation of Rho-GDI

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Ca2+-independent smooth muscle contraction. a novel function for integrin-linked kinase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Hydrogen peroxide increases extracellular matrix mRNA through TGF-beta in human mesangial cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Release of an invasion promoter E-cadherin fragment by matrilysin and stromelysin-1.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Rac1 in human breast cancer: overexpression, mutation analysis, and characterization of a new isoform, Rac1b

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Cell movement is guided by the rigidity of the substrate

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Adhesion to the extracellular matrix regulates the coupling of the small GTPase Rac to its effector PAK.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Cloning of a novel human Rac1b splice variant with increased expression in colorectal tumors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

The stromal proteinase MMP3/stromelysin-1 promotes mammary carcinogenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Matrix metalloproteinase stromelysin-1 triggers a cascade of molecular alterations that leads to stable epithelial-to-mesenchymal conversion and a premalignant phenotype in mammary epithelial cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Cell locomotion and focal adhesions are regulated by substrate flexibility

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Misregulation of stromelysin-1 expression in mouse mammary tumor cells accompanies acquisition of stromelysin-1-dependent invasive properties

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Expression of most matrix metalloproteinase family members in breast cancer represents a tumor-induced host response.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Matrix metalloproteinases are expressed during ductal and alveolar mammary morphogenesis, and misregulation of stromelysin-1 in transgenic mice induces unscheduled alveolar development

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Requirement for posttranslational processing of Rac GTP-binding proteins for activation of human neutrophil NADPH oxidase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Interaction of Rac with p67phox and regulation of phagocytic NADPH oxidase activity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Carboxyl-terminal isoprenylation of ras-related GTP-binding proteins encoded by rac1, rac2, and ralA

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Proteinases of the mammary gland: developmental regulation in vivo and vectorial secretion in culture

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Snail1, Snail2, and E47 promote mammary epithelial branching morphogenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Cell-cycle control by physiological matrix elasticity and in vivo tissue stiffening

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Increased Rac1b expression sustains colorectal tumor cell survival

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Expression of Rac1b stimulates NF-kappaB-mediated cell survival and G1/S progression

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Patterns of fibronectin deposition in normal and neoplastic fibroblasts and mammary tissue

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Isoprenylation of the low molecular mass GTP-binding proteins rac 1 and rac 2: possible role in membrane localization

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Post-translational processing of rac p21s is important both for their interaction with the GDP/GTP exchange proteins and for their activation of NADPH oxidase

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Emerging role of ILK and ELMO2 in the integration of adhesion and migration pathways

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

An extended relationship for the characterization of Young's modulus and Poisson's ratio of tunable polyacrylamide gels.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Regulation of cell-matrix adhesion dynamics and Rac-1 by integrin linked kinase.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Extracellular matrix rigidity governs smooth muscle cell motility in a biphasic fashion

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

The Rac1 C-terminal polybasic region regulates the nuclear localization and protein degradation of Rac1.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Micropatterning tractional forces in living cells

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Modulation of small G protein isoprenylation by anticancer monoterpenes in in situ mammary gland epithelial cells

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3469523

Integrin engagement suppresses RhoA activity via a c-Src-dependent mechanism

22 September 2018

1 reference

12 December 2020

Human hepatocellular carcinomas with "Stemness"-related marker expression: keratin 19 expression and a poor prognosis

1 reference

12 December 2020

A single nucleotide polymorphism in the matrix metalloproteinase-3 promoter enhances breast cancer susceptibility

1 reference

12 December 2020

An assay for transforming growth factor-beta using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct

1 reference

12 December 2020

The matrix metalloproteinase matrilysin influences early-stage mammary tumorigenesis

1 reference

12 December 2020

Matrix metalloproteinase-1 and -3 in breast cancer: correlation with progesterone receptors and other clinicopathologic features

1 reference

12 December 2020

Identifiers

DOI

10.1091/MBC.E12-02-0166

1 reference

release_ggrx2bdrojavbeuzi2xqe2zese

13 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ggrx2bdrojavbeuzi2xqe2zese

24 November 2022

mapped directly with Wikidata item

1 reference

13 August 2017

PubMed publication ID

22918955

1 reference