(Q36315745)

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Mutations in envelope gp120 can impact proteolytic processing of the gp160 precursor and thereby affect neutralization sensitivity of human immunodeficiency virus type 1 pseudoviruses.

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17855534%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Mutations in envelope gp120 can impact proteolytic processing of the gp160 precursor and thereby affect neutralization sensitivity of human immunodeficiency virus type 1 pseudoviruses (English)

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7 January 2020

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7 January 2020

Barbra A Richardson

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Barbra A Richardson

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7 January 2020

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Wendy M Blay

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7 January 2020

Theresa Kasprzyk

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7 January 2020

Lynda Misher

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7 January 2020

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12 September 2007

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7 January 2020

Journal of Virology

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7 January 2020

81

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7 January 2020

23

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7 January 2020

13037-13049

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7 January 2020

Macaques infected with a CCR5-tropic simian/human immunodeficiency virus (SHIV) develop broadly reactive anti-HIV neutralizing antibodies

1 reference

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30 September 2017

Antigenicity and immunogenicity of HIV-1 consensus subtype B envelope glycoproteins

1 reference

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Specific amino acids in the N-terminus of the gp41 ectodomain contribute to the stabilization of a soluble, cleaved gp140 envelope glycoprotein from human immunodeficiency virus type 1.

1 reference

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Impact of natural polymorphism within the gp41 cytoplasmic tail of human immunodeficiency virus type 1 on the intracellular distribution of envelope glycoproteins and viral assembly.

1 reference

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Distribution and three-dimensional structure of AIDS virus envelope spikes

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30 September 2017

Nature of nonfunctional envelope proteins on the surface of human immunodeficiency virus type 1.

1 reference

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30 September 2017

A mutation in the human immunodeficiency virus type 1 Gag protein destabilizes the interaction of the envelope protein subunits gp120 and gp41.

1 reference

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30 September 2017

Mutations at the C-terminus of the simian immunodeficiency virus envelope glycoprotein affect gp120-gp41 stability on virions

1 reference

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Consistent patterns of change during the divergence of human immunodeficiency virus type 1 envelope from that of the inoculated virus in simian/human immunodeficiency virus-infected macaques

1 reference

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Stoichiometry of envelope glycoprotein trimers in the entry of human immunodeficiency virus type 1

1 reference

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The impact of envelope glycoprotein cleavage on the antigenicity, infectivity, and neutralization sensitivity of Env-pseudotyped human immunodeficiency virus type 1 particles

1 reference

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Identification of a new quaternary neutralizing epitope on human immunodeficiency virus type 1 virus particles

1 reference

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Stoichiometry of antibody neutralization of human immunodeficiency virus type 1.

1 reference

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30 September 2017

Structure of an unliganded simian immunodeficiency virus gp120 core

1 reference

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Selective recognition of oligomeric HIV-1 primary isolate envelope glycoproteins by potently neutralizing ligands requires efficient precursor cleavage.

1 reference

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Basic statistical considerations in virological experiments

1 reference

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30 September 2017

Evolutionary dynamics of the glycan shield of the human immunodeficiency virus envelope during natural infection and implications for exposure of the 2G12 epitope

1 reference

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MEGA3: Integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment

1 reference

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30 September 2017

N-linked glycosylation of the V3 loop and the immunologically silent face of gp120 protects human immunodeficiency virus type 1 SF162 from neutralization by anti-gp120 and anti-gp41 antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169095

30 September 2017

Antibody neutralization and escape by HIV-1

1 reference

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Rapid evolution of the neutralizing antibody response to HIV type 1 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169095

30 September 2017

Nonneutralizing antibodies to the CD4-binding site on the gp120 subunit of human immunodeficiency virus type 1 do not interfere with the activity of a neutralizing antibody against the same site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169095

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HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169095

30 September 2017

Concordant modulation of neutralization resistance and high infectivity of the primary human immunodeficiency virus type 1 MN strain and definition of a potential gp41 binding site in gp120.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169095

30 September 2017

Heterogeneity of envelope molecules expressed on primary human immunodeficiency virus type 1 particles as probed by the binding of neutralizing and nonneutralizing antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169095

30 September 2017

Precursor processing by kex2/furin proteases

1 reference

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Furin at the cutting edge: from protein traffic to embryogenesis and disease

1 reference

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30 September 2017

The mannose-dependent epitope for neutralizing antibody 2G12 on human immunodeficiency virus type 1 glycoprotein gp120.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169095

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Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy.

1 reference

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Enhancing the proteolytic maturation of human immunodeficiency virus type 1 envelope glycoproteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169095

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A potent cross-clade neutralizing human monoclonal antibody against a novel epitope on gp41 of human immunodeficiency virus type 1.

1 reference

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Molecular basis for high virulence of Hong Kong H5N1 influenza A viruses

1 reference

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Analysis of dominant-negative effects of mutant Env proteins of human immunodeficiency virus type 1.

1 reference

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The ability of an oligomeric human immunodeficiency virus type 1 (HIV-1) envelope antigen to elicit neutralizing antibodies against primary HIV-1 isolates is improved following partial deletion of the second hypervariable region

1 reference

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Intracellular functions of N-linked glycans

1 reference

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Improved elicitation of neutralizing antibodies against primary human immunodeficiency viruses by soluble stabilized envelope glycoprotein trimers

1 reference

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30 September 2017

Immunogenicity and protective efficacy of oligomeric human immunodeficiency virus type 1 gp140.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169095

30 September 2017

Maturation of HIV envelope glycoprotein precursors by cellular endoproteases

1 reference

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Processing, stability, and receptor binding properties of oligomeric envelope glycoprotein from a primary HIV-1 isolate

1 reference

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A global neutralization resistance phenotype of human immunodeficiency virus type 1 is determined by distinct mechanisms mediating enhanced infectivity and conformational change of the envelope complex

1 reference

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A recombinant human immunodeficiency virus type 1 envelope glycoprotein complex stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits is an antigenic mimic of the trimeric virion-associated structure

1 reference

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The long cytoplasmic tail of gp41 is required in a cell type-dependent manner for HIV-1 envelope glycoprotein incorporation into virions

1 reference

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Understanding influenza virus pathogenicity

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Vif and the p55(Gag) polyprotein of human immunodeficiency virus type 1 are present in colocalizing membrane-free cytoplasmic complexes

1 reference

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Regulation of endosome sorting by a specific PP2A isoform

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Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

1 reference

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A conserved HIV gp120 glycoprotein structure involved in chemokine receptor binding

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Neutralization of human immunodeficiency virus type 1 by antibody to gp120 is determined primarily by occupancy of sites on the virion irrespective of epitope specificity

1 reference

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The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools

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Specific N-linked and O-linked glycosylation modifications in the envelope V1 domain of simian immunodeficiency virus variants that evolve in the host alter recognition by neutralizing antibodies

1 reference

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HIV-1 infection of non-dividing cells: evidence that the amino-terminal basic region of the viral matrix protein is important for Gag processing but not for post-entry nuclear import.

1 reference

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Human immunodeficiency virus type 1 mutants that escape neutralization by human monoclonal antibody IgG1b12. off.

1 reference

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30 September 2017

The Vif and Gag proteins of human immunodeficiency virus type 1 colocalize in infected human T cells

1 reference

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Microvesicles are a source of contaminating cellular proteins found in purified HIV-1 preparations

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Autologous and heterologous neutralizing antibody responses following initial seroconversion in human immunodeficiency virus type 1-infected individuals.

1 reference

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Increased envelope spike density and stability are not required for the neutralization resistance of primary human immunodeficiency viruses

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30 September 2017

Humoral response to oligomeric human immunodeficiency virus type 1 envelope protein.

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30 September 2017

Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1

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30 September 2017

Domains of the human immunodeficiency virus type 1 matrix and gp41 cytoplasmic tail required for envelope incorporation into virions.

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30 September 2017

Role of the matrix protein in the virion association of the human immunodeficiency virus type 1 envelope glycoprotein

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Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody

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Analysis of the cleavage site of the human immunodeficiency virus type 1 glycoprotein: requirement of precursor cleavage for glycoprotein incorporation

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A large array of human monoclonal antibodies to type 1 human immunodeficiency virus from combinatorial libraries of asymptomatic seropositive individuals

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30 September 2017

The matrix protein of human immunodeficiency virus type 1 is required for incorporation of viral envelope protein into mature virions

1 reference

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Effects of deletions in the cytoplasmic domain on biological functions of human immunodeficiency virus type 1 envelope glycoproteins

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30 September 2017

Inhibition of furin-mediated cleavage activation of HIV-1 glycoprotein gp160

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Truncation of the human immunodeficiency virus type 1 transmembrane glycoprotein cytoplasmic domain blocks virus infectivity

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30 September 2017

A broadly neutralizing human monoclonal antibody against gp41 of human immunodeficiency virus type 1.

1 reference

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30 September 2017

An unrelated monoclonal antibody neutralizes human immunodeficiency virus type 1 by binding to an artificial epitope engineered in a functionally neutral region of the viral envelope glycoproteins

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Cell membrane vesicles are a major contaminant of gradient-enriched human immunodeficiency virus type-1 preparations

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29 June 2018

The ratio of defective HIV-1 particles to replication-competent infectious virions

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29 June 2018

Endoproteolytic cleavage of gp160 is required for the activation of human immunodeficiency virus

1 reference

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29 June 2018

Immunological analysis of human immunodeficiency virus type 1 envelope glycoprotein proteolytic cleavage

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29 June 2018

A comparative immunogenicity study in rabbits of disulfide-stabilized, proteolytically cleaved, soluble trimeric human immunodeficiency virus type 1 gp140, trimeric cleavage-defective gp140 and monomeric gp120.

1 reference

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22 September 2018

Membrane embedded HIV-1 envelope on the surface of a virus-like particle elicits broader immune responses than soluble envelopes

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The production of cleaved, trimeric human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein vaccine antigens and infectious pseudoviruses using linear polyethylenimine as a transfection reagent

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22 September 2018

HIV-1 envelope pseudotyped viral vectors and infectious molecular clones expressing the same envelope glycoprotein have a similar neutralization phenotype, but culture in peripheral blood mononuclear cells is associated with decreased neutralization

1 reference

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22 September 2018

Structural investigation of the HIV-1 envelope glycoprotein gp160 cleavage site 3: role of site-specific mutations

1 reference

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22 September 2018

HIV-1 acute infection env glycomutants designed from 3D model: effects on processing, antigenicity, and neutralization sensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169095

22 September 2018

HIV type 1 variants transmitted to women in Kenya require the CCR5 coreceptor for entry, regardless of the genetic complexity of the infecting virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169095

22 September 2018

Multigene DNA prime-boost vaccines for SHIV89.6P

1 reference

https://pubmed.ncbi.nlm.nih.gov/17855534

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.01215-07

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17855534%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17855534%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17855534%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

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