(Q36318852)

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NAD(P)H cytochrome b5 oxidoreductase deficiency in Leishmania major results in impaired linoleate synthesis followed by increased oxidative stress and cell death

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22923617%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

NAD(P)H cytochrome b5 oxidoreductase deficiency in Leishmania major results in impaired linoleate synthesis followed by increased oxidative stress and cell death (English)

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22923617%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

Leishmania major

object named as

Leishmania major

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based on heuristic

inferred from title

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based on heuristic

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Sumit Sen Santara

2

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Europe PubMed Central

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30 August 2019

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Supratim Mukherjee

1

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30 August 2019

Shantanabha Das

3

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30 August 2019

Moumita Bose

4

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30 August 2019

Jayasree Roy

5

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30 August 2019

Subrata Adak

6

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30 August 2019

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publication date

25 August 2012

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30 August 2019

Journal of Biological Chemistry

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30 August 2019

287

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30 August 2019

42

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30 August 2019

34992-35003

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30 August 2019

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3471740/fullTextXML

based on heuristic

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Dietary linoleate preserves cardiolipin and attenuates mitochondrial dysfunction in the failing rat heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

Role of heme and heme-proteins in trypanosomatid essential metabolic pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

Ncb5or deficiency increases fatty acid catabolism and oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

Genetic and chemical evaluation of Trypanosoma brucei oleate desaturase as a candidate drug target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

Ascorbate peroxidase from Leishmania major controls the virulence of infective stage of promastigotes by regulating oxidative stress.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

The flavoheme reductase Ncb5or protects cells against endoplasmic reticulum stress-induced lipotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

A fatty-acid synthesis mechanism specialized for parasitism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

The reductase NCB5OR is responsive to the redox status in beta-cells and is not involved in the ER stress response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

Biosynthesis of polyunsaturated fatty acids in lower eukaryotes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

Role of cardiolipin alterations in mitochondrial dysfunction and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

The genome of the kinetoplastid parasite, Leishmania major

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

GAPDH as a housekeeping gene: analysis of GAPDH mRNA expression in a panel of 72 human tissues

1 reference

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30 September 2017

Absence of a reductase, NCB5OR, causes insulin-deficient diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

NCB5OR is a novel soluble NAD(P)H reductase localized in the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

A simple method for the isolation and purification of total lipides from animal tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

The 1.2 A structure of the human sulfite oxidase cytochrome b(5) domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

Fatty acid synthesis in African trypanosomes: a solution to the myristate mystery.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

Nonalcoholic steatosis and steatohepatitis. I. Molecular mechanism for polyunsaturated fatty acid regulation of gene transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

Fatty acid regulation of gene transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

Leptin, troglitazone, and the expression of sterol regulatory element binding proteins in liver and pancreatic islets

1 reference

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30 September 2017

The biosynthesis and functional role of cardiolipin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

Lipotoxic heart disease in obese rats: implications for human obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

Identification of a cytochrome b-type NAD(P)H oxidoreductase ubiquitously expressed in human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

Molecular basis of sulfite oxidase deficiency from the structure of sulfite oxidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

A novel cytochrome b5-like domain is linked to the carboxyl terminus of the Saccharomyces cerevisiae delta-9 fatty acid desaturase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

Effect of fatty acids on energy coupling processes in mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

Free, long-chain, polyunsaturated fatty acids reduce membrane electrical excitability in neonatal rat cardiac myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

Total enzymic synthesis of cholesterol from lanosterol. Cytochrome b5-dependence of 4-methyl sterol oxidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

A function of cytochrome b5 in fatty acid desaturation by rat liver microsomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

Three-dimensional structure of flavocytochrome b2 from baker's yeast at 3.0-A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

The sequence of squash NADH:nitrate reductase and its relationship to the sequences of other flavoprotein oxidoreductases. A family of flavoprotein pyridine nucleotide cytochrome reductases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

Decoupling of oxidative phosphorylation and photophosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

Mechanism of C-5 double bond introduction in the biosynthesis of cholesterol by rat liver microsomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

Effect of long-chain fatty acids and acyl-CoA on mitochondrial permeability, transport, and energy-coupling processes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

Uncoupling of oxidative phosphorylation. 2. Alternative mechanisms: intrinsic uncoupling or decoupling?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

30 September 2017

Endoplasmic reticulum stress-induced apoptosis in Leishmania through Ca2+-dependent and caspase-independent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

29 June 2018

Overexpression of mitochondrial Leishmania major ascorbate peroxidase enhances tolerance to oxidative stress-induced programmed cell death and protein damage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

29 June 2018

Leishmania major encodes an unusual peroxidase that is a close homologue of plant ascorbate peroxidase: a novel role of the transmembrane domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

29 June 2018

Decreased cardiolipin synthesis corresponds with cytochrome c release in palmitate-induced cardiomyocyte apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

29 June 2018

Characterization of the respiratory chain of Leishmania donovani promastigotes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

29 June 2018

Evidence for the participation of cytochrome b5 in plasmalogen biosynthesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

29 June 2018

Construction and sequence of cDNA for rat liver stearyl coenzyme A desaturase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

29 June 2018

Fatty acid uncoupling of oxidative phosphorylation in rat liver mitochondria.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

29 June 2018

Leishmania donovani: use of two different, commercially available, chemically defined media for the continuous in vitro cultivation of promastigotes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

29 June 2018

Direct desaturation of eicosatrienoyl lecithin to arachidonoyl lecithin by rat liver microsomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

29 June 2018

Highly specific methyl-end fatty-acid desaturases of trypanosomatids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

22 September 2018

Leishmania major ascorbate peroxidase overexpression protects cells against reactive oxygen species-mediated cardiolipin oxidation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

22 September 2018

Loss of Ncb5or results in impaired fatty acid desaturation, lipoatrophy, and diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

22 September 2018

Conservation of the pro-apoptotic nuclease activity of endonuclease G in unicellular trypanosomatid parasites

1 reference

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22 September 2018

Functional characterization of front-end desaturases from trypanosomatids depicts the first polyunsaturated fatty acid biosynthetic pathway from a parasitic protozoan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

22 September 2018

Characterization of the Aspergillus parasiticus delta12-desaturase gene: a role for lipid metabolism in the Aspergillus-seed interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

22 September 2018

Increase in cytosolic Ca2+ levels through the activation of non-selective cation channels induced by oxidative stress causes mitochondrial depolarization leading to apoptosis-like death in Leishmania donovani promastigotes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3471740

22 September 2018

Hydrogen peroxide induces apoptosis-like death in Leishmania donovani promastigotes

1 reference

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1 reference

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Genetic connection between fatty acid metabolism and sporulation in Aspergillus nidulans

1 reference

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22 September 2018

Specialized fatty acid synthesis in African trypanosomes: myristate for GPI anchors

1 reference

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1 reference

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22 September 2018

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1 reference

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22 September 2018

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1 reference

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The 1.2 Å structure of the human sulfite oxidase cytochromeb5domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.389338

21 January 2018

Elongation of polyunsaturated fatty acids in trypanosomatids

1 reference

https://pubmed.ncbi.nlm.nih.gov/22923617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/22923617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/22923617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondria uncoupling by a long chain fatty acyl analogue

1 reference

https://pubmed.ncbi.nlm.nih.gov/22923617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/22923617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of reductase domain cluster 1 acidic residues in neuronal nitric-oxide synthase. Characterization of the FMN-FREE enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/22923617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

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12 December 2020

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1 reference

https://pubmed.ncbi.nlm.nih.gov/22923617

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty acid synthesis by elongases in trypanosomes

1 reference

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The Molar Light Absorption of Pyridine Ferroprotoporphrin (Pyridine Haemochromogen)

1 reference

31 May 2024

https://opencitations.net/index/api/v1/citations/10.3891/ACTA.CHEM.SCAND.07-1284

Identifiers

10.1074/JBC.M112.389338

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22923617%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22923617%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22923617%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

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