(Q36321255)

http://europepmc.org/abstract/PMC/5456119

18 May 2018

title

A conserved NAD+ binding pocket that regulates protein-protein interactions during aging (English)

1 reference

http://europepmc.org/abstract/PMC/5456119

18 May 2018

1 reference

protein-protein interaction

1 reference

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28336669%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Jun Li

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28336669%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Dapeng Zhang

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28336669%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Basil P Hubbard

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28336669%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Alvin J Y Ling

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28336669%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Luis A Rajman

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28336669%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Vera Gorbunova

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28336669%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

David A. Sinclair

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28336669%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

12

Clemens Steegborn

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28336669%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

author name string

Michael S Bonkowski

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28336669%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Sébastien Moniot

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28336669%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Bo Qin

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28336669%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Zhenkun Lou

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28336669%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

language of work or name

English

0 references

publication date

1 March 2017

1 reference

http://europepmc.org/abstract/PMC/5456119

18 May 2018

published in

Science

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28336669%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

volume

355

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28336669%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

issue

6331

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28336669%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

page(s)

1312-1317

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28336669%20AND%20SRC:MED&resulttype=core&format=json

Slowing ageing by design: the rise of NAD(+) and sirtuin-activating compounds

2 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5456119

Version 4.0 of PaxDb: Protein abundance data, integrated across model organisms, tissues, and cell-lines.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5456119

Lifespan and healthspan extension by resveratrol

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5456119

NAD+ and sirtuins in aging and disease

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5456119

The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5456119

A high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complex

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5456119

Regulation of poly(ADP-ribose) polymerase-1-dependent gene expression through promoter-directed recruitment of a nuclear NAD+ synthase

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5456119

Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5456119

PARP-1 regulates chromatin structure and transcription through a KDM5B-dependent pathway

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5456119

Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5456119

Mammalian sirtuins: biological insights and disease relevance

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5456119

The secret life of NAD+: an old metabolite controlling new metabolic signaling pathways

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5456119

Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5456119

Analysis of DBC1 and its homologs suggests a potential mechanism for regulation of sirtuin domain deacetylases by NAD metabolites

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5456119

DBC1 is a negative regulator of SIRT1

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5456119

Changes in DNA repair during aging.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5456119

Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5456119

Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5456119

DNA repair, genome stability, and aging

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5456119

Structures and mechanisms of Nudix hydrolases.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5456119

FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5456119

DBC2, a candidate for a tumor suppressor gene involved in breast cancer

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5456119

A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5456119

Poly(ADP-ribose) polymerase activity in mononuclear leukocytes of 13 mammalian species correlates with species-specific life span

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5456119

Evidence for a common mechanism of SIRT1 regulation by allosteric activators

29 June 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD8242

The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD8242

Structural studies of the PARP-1 BRCT domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD8242

The DNA binding and catalytic domains of poly(ADP-ribose) polymerase 1 cooperate in the regulation of chromatin structure and transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD8242

Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD8242

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD8242

Kalign--an accurate and fast multiple sequence alignment algorithm

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD8242

PROMALS: towards accurate multiple sequence alignments of distantly related proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD8242

The HHpred interactive server for protein homology detection and structure prediction

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD8242

JPred: a consensus secondary structure prediction server

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD8242

Comparative protein modelling by satisfaction of spatial restraints

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD8242

Relationship between multiple sequence alignments and quality of protein comparative models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD8242

KoBaMIN: a knowledge-based minimization web server for protein structure refinement

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD8242

DNA repair by homologous recombination, but not by nonhomologous end joining, is elevated in breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD8242

SIRT6 promotes DNA repair under stress by activating PARP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD8242

Macrodomain-containing proteins are new mono-ADP-ribosylhydrolases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD8242

21 January 2018

Identifiers

DOI

10.1126/SCIENCE.AAD8242

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28336669%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28336669%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

1 reference