(Q36324945)

13 August 2017

Ascorbate-dependent vasopressor synthesis: a rationale for vitamin C administration in severe sepsis and septic shock? (English)

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13 August 2017

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1

Anitra C Carr

1 reference

13 August 2017

Ramesh Natarajan

4

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author name string

Geoffrey M Shaw

series ordinal

2

1 reference

13 August 2017

Alpha A Fowler

series ordinal

3

1 reference

13 August 2017

27 November 2015

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13 August 2017

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13 August 2017

19

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13 August 2017

418

1 reference

https://scigraph.springernature.com/pub.10.1186/s13054-015-1131-2

13 August 2017

0 references

cites work

New Reference Values for Vitamin C Intake

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Restoring physiological levels of ascorbate slows tumor growth and moderates HIF-1 pathway activity in Gulo(-/-) mice

30 September 2017

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30 September 2017

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A rare presentation of an ancient disease: scurvy presenting as orthostatic hypotension

30 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Phase I safety trial of intravenous ascorbic acid in patients with severe sepsis.

30 September 2017

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Evaluation of vitamin C for adjuvant sepsis therapy

30 September 2017

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Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012

30 September 2017

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Ascorbic acid efficiently enhances neuronal synthesis of norepinephrine from dopamine

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Mechanisms of ascorbic acid stimulation of norepinephrine synthesis in neuronal cells

30 September 2017

1 reference

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Ascorbic acid: chemistry, biology and the treatment of cancer.

30 September 2017

1 reference

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Bench-to-bedside review: Vasopressin in the management of septic shock

30 September 2017

1 reference

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Norepinephrine or dopamine for septic shock: systematic review of randomized clinical trials

30 September 2017

1 reference

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Receptor-mediated enhancement of beta adrenergic drug activity by ascorbate in vitro and in vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Resuscitation after severe burn injury using high-dose ascorbic acid: a retrospective review

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Is vitamin C supplementation beneficial? Lessons learned from randomised controlled trials

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Vitamin C requirements in parenteral nutrition

30 September 2017

1 reference

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Vasopressin versus norepinephrine infusion in patients with septic shock.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Mechanisms of sepsis-induced cardiac dysfunction

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

The vasopressin system: physiology and clinical strategies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Organ dysfunction in patients with severe sepsis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Vitamin C pharmacokinetics: implications for oral and intravenous use.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

The epidemiology of sepsis in the United States from 1979 through 2000

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

New insights into copper monooxygenases and peptide amidation: structure, mechanism and function

30 September 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

30 September 2017

https://api.crossref.org/works/10.1186%2FS13054-015-1131-2

Catecholamine dependency in a polytrauma patient: relative adrenal insufficiency?

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Toward a new recommended dietary allowance for vitamin C based on antioxidant and health effects in humans

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Does vitamin C act as a pro-oxidant under physiological conditions?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Antioxidant status in patients with acute respiratory distress syndrome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Plasma concentrations of cytokines, their soluble receptors, and antioxidant vitamins can predict the development of multiple organ failure in patients at risk.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

C-terminal amidated peptides: production by the in vitro enzymatic amidation of glycine-extended peptides and the importance of the amide to bioactivity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

The biochemical functions of ascorbic acid

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Distribution of ascorbic acid, metabolites and analogues in man and animals

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Scurvy: historically a plague of the sailor that remains a consideration in the modern intensive care unit.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Clinical management of the cardiovascular failure in sepsis.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Centrally administered ascorbic acid induces antidiuresis, natriuresis and neurohypophyseal hormone release in rats

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

The effect of stress and corticotrophin on the concentrations of vitamin C in blood and tissues of the rat

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Ascorbic acid dynamics in the seriously ill and injured

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Total vitamin C, ascorbic acid, and dehydroascorbic acid concentrations in plasma of critically ill patients.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

The retention of ascorbic acid by guinea-pig tissues

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Changes relevant to catecholamine metabolism in liver and brain of ascorbic acid deficient guinea-pigs

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Distribution of vitamin C is tissue specific with early saturation of the brain and adrenal glands following differential oral dose regimens in guinea pigs.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Hospitalizations, costs, and outcomes of severe sepsis in the United States 2003 to 2007.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Dietary ascorbate intake affects steady state tissue concentrations in vitamin C-deficient mice: tissue deficiency after suboptimal intake and superior bioavailability from a food source (kiwifruit)

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

The vasopressin and copeptin response to infection, severe sepsis, and septic shock

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Human adrenal glands secrete vitamin C in response to adrenocorticotrophic hormone.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Copeptin, a stable peptide of the arginine vasopressin precursor, is elevated in hemorrhagic and septic shock.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Rapid increase in hospitalization and mortality rates for severe sepsis in the United States: a trend analysis from 1993 to 2003.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Antioxidant-independent ascorbate enhancement of catecholamine-induced contractions of vascular smooth muscle

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Impaired adrenal catecholamine system function in mice with deficiency of the ascorbic acid transporter (SVCT2).

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Circulating vasopressin levels in septic shock.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Depletion of neurohypophyseal content of vasopressin in septic shock.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Multiple organ dysfunction dramatically improving with the infusion of vitamin C: more support for the persistence of scurvy in our "welfare" society

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Adrenal failure in the critically ill.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Effects of chronic ascorbic acid deficiency on guinea pig lysosomal hydrolase activities

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4661979

Severe sepsis and septic shock

22 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FS13054-015-1131-2

Stress-Induced Change in Tissue Levels of Ascorbic Acid and Histamine in Rats

21 January 2018

1 reference

12 December 2020

Ascorbic acid specifically enhances dopamine beta-monooxygenase activity in resting and stimulated chromaffin cells

1 reference

12 December 2020

The role of vasopressin in blood pressure maintenance in diabetic orthostatic hypotension

1 reference

12 December 2020

The clinical effects of vitamin C supplementation in elderly hospitalised patients with acute respiratory infections

1 reference

12 December 2020

Vasopressin deficiency contributes to the vasodilation of septic shock

1 reference

12 December 2020

Reduction of resuscitation fluid volumes in severely burned patients using ascorbic acid administration: a randomized, prospective study

1 reference

12 December 2020

Ascorbic acid synthesis in normal and drug-treated rats, studied with L-ascorbic-1-C14 acid

1 reference

12 December 2020

Metabolic interactions between L-ascorbic acid and drugs

1 reference

12 December 2020

Copeptin and arginine vasopressin concentrations in critically ill patients

1 reference

12 December 2020

Pathophysiology of sepsis

1 reference

12 December 2020

Assessment of pro-vasopressin and pro-adrenomedullin as predictors of 28-day mortality in septic shock patients

1 reference

12 December 2020

Severe sepsis and septic shock

1 reference

12 December 2020

10.1186/S13054-015-1131-2

Identifiers

DOI

1 reference

Dimensions Publication ID

13 August 2017

0 references

1 reference

13 August 2017

PubMed publication ID

26612352

1 reference