(Q36326279)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26056084%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

title

The PARP inhibitor olaparib enhances the sensitivity of Ewing sarcoma to trabectedin (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26056084%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

3

1 reference

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16 February 2020

Guillem Pascual-Pasto

8

1 reference

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16 February 2020

Enrique de Alava

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26056084%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

10

Monica Vila-Ubach

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26056084%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

author name string

José Luis Ordóñez

1

1 reference

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16 February 2020

Ana Teresa Amaral

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26056084%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

David Herrero-Martín

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26056084%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

María del Carmen García-Macías

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26056084%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Vicky Sevillano

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26056084%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Diego Alonso

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26056084%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Laura San-Segundo

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26056084%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Telmo Rodrigues

11

1 reference

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16 February 2020

Susana Fraile

12

1 reference

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16 February 2020

Cristina Teodosio

13

1 reference

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16 February 2020

Agustín Mayo-Iscar

14

1 reference

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16 February 2020

Miguel Aracil

15

1 reference

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16 February 2020

Carlos María Galmarini

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26056084%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Oscar M Tirado

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26056084%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Jaume Mora

18

1 reference

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16 February 2020

language of work or name

English

0 references

publication date

1 August 2015

1 reference

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16 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26056084%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

volume

6

1 reference

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16 February 2020

issue

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26056084%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

page(s)

18875-18890

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26056084%20AND%20SRC:MED&resulttype=core&format=json

Trabectedin efficacy in Ewing sarcoma is greatly increased by combination with anti-IGF signaling agents.

16 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662461

Targeting the DNA repair pathway in Ewing sarcoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662461

Caveolin-1 is down-regulated in alveolar rhabdomyosarcomas and negatively regulates tumor growth

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662461

The genomic landscape of pediatric Ewing sarcoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662461

Patient-derived xenograft models: an emerging platform for translational cancer research

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662461

Patient-derived xenograft models in gynecologic malignancies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662461

Characterization of human mesenchymal stem cells from ewing sarcoma patients. Pathogenetic implications

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662461

Patient-derived xenograft models to improve targeted therapy in epithelial ovarian cancer treatment

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662461

Dual targeting of EWS-FLI1 activity and the associated DNA damage response with trabectedin and SN38 synergistically inhibits Ewing sarcoma cell growth

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662461

Appraising iniparib, the PARP inhibitor that never was--what must we learn?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662461

Combining PARP-1 inhibition and radiation in Ewing sarcoma results in lethal DNA damage

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662461

Systematic identification of genomic markers of drug sensitivity in cancer cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662461

PARP-1 inhibition as a targeted strategy to treat Ewing's sarcoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662461

1q gain and CDT2 overexpression underlie an aggressive and highly proliferative form of Ewing sarcoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662461

Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662461

Ecteinascidin 743 interferes with the activity of EWS-FLI1 in Ewing sarcoma cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662461

How to kill tumor cells with inhibitors of poly(ADP-ribosyl)ation.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662461

Poly(ADP-ribose) polymerase inhibitors as promising cancer therapeutics

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662461

Homologous recombination in cancer development, treatment and development of drug resistance.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662461

Stable interference of EWS-FLI1 in an Ewing sarcoma cell line impairs IGF-1/IGF-1R signalling and reveals TOPK as a new target

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662461

Trabectedin (ET-743) promotes differentiation in myxoid liposarcoma tumors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662461

A pivotal role for heat shock protein 90 in Ewing sarcoma resistance to anti-insulin-like growth factor 1 receptor treatment: in vitro and in vivo study.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662461

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662461

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662461

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662461

Enhanced poly(adenosine diphosphate ribose) polymerase activity and gene expression in Ewing's sarcoma cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662461

Fluorescence in situ hybridization analysis of CCND3 gene as marker of progression in bladder carcinoma.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662461

Primary disseminated multifocal Ewing sarcoma: results of the Euro-EWING 99 trial.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662461

The pediatric preclinical testing program: description of models and early testing results.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4662461

Computerized quantitation of synergism and antagonism of taxol, topotecan, and cisplatin against human teratocarcinoma cell growth: a rational approach to clinical protocol design

22 September 2018

1 reference

12 December 2020

Molecular precision chemotherapy: overcoming resistance to targeted therapies?

1 reference

12 December 2020

The value of local treatment in patients with primary, disseminated, multifocal Ewing sarcoma (PDMES)

1 reference

12 December 2020

Cyclin D3 gene amplification in bladder carcinoma in situ

1 reference

12 December 2020

Identifiers

DOI

10.18632/ONCOTARGET.4303

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26056084%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26056084%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

PubMed publication ID

26056084

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26056084%20AND%20SRC:MED&resulttype=core&format=json