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Glucose transporter 4: cycling, compartments and controversies
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scholarly article
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Europe PubMed Central
PMCID
1369215
retrieved
13 August 2017
review article
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Europe PubMed Central
title
Glucose transporter 4: cycling, compartments and controversies
(English)
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stated in
Europe PubMed Central
PMCID
1369215
retrieved
13 August 2017
main subject
glycobiology
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author
Amira Klip
series ordinal
2
object named as
Amira Klip
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Europe PubMed Central
retrieved
13 August 2017
PMCID
1369215
author name string
Chandrasagar B Dugani
series ordinal
1
1 reference
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Europe PubMed Central
PMCID
1369215
retrieved
13 August 2017
publication date
1 December 2005
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Europe PubMed Central
PMCID
1369215
retrieved
13 August 2017
published in
EMBO Reports
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stated in
Europe PubMed Central
PMCID
1369215
retrieved
13 August 2017
volume
6
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stated in
Europe PubMed Central
PMCID
1369215
retrieved
13 August 2017
page(s)
1137-1142
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stated in
Europe PubMed Central
PMCID
1369215
retrieved
13 August 2017
issue
12
1 reference
stated in
Europe PubMed Central
PMCID
1369215
retrieved
13 August 2017
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Turning signals on and off: GLUT4 traffic in the insulin-signaling highway
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Sortilin is essential and sufficient for the formation of Glut4 storage vesicles in 3T3-L1 adipocytes
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PubMed Central
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30 September 2017
AS160, the Akt substrate regulating GLUT4 translocation, has a functional Rab GTPase-activating protein domain
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PubMed Central
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30 September 2017
Insulin stimulates the halting, tethering, and fusion of mobile GLUT4 vesicles in rat adipose cells.
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p115 Interacts with the GLUT4 vesicle protein, IRAP, and plays a critical role in insulin-stimulated GLUT4 translocation
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Insulin signal transduction in human skeletal muscle: identifying the defects in Type II diabetes
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Positive and negative regulation of insulin signaling through IRS-1 phosphorylation
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Identification of 80K-H as a protein involved in GLUT4 vesicle trafficking
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30 September 2017
Adipocytes from Munc18c-null mice show increased sensitivity to insulin-stimulated GLUT4 externalization
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Insulin and hypertonicity recruit GLUT4 to the plasma membrane of muscle cells by using N-ethylmaleimide-sensitive factor-dependent SNARE mechanisms but different v-SNAREs: role of TI-VAMP.
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30 September 2017
Insulin but not PDGF relies on actin remodeling and on VAMP2 for GLUT4 translocation in myoblasts
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30 September 2017
Insulin stimulation of GLUT4 exocytosis, but not its inhibition of endocytosis, is dependent on RabGAP AS160.
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PubMed Central
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30 September 2017
Insulin increases cell surface GLUT4 levels by dose dependently discharging GLUT4 into a cell surface recycling pathway
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PubMed Central
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30 September 2017
The synaptic vesicle cycle
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PubMed Central
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30 September 2017
Entry of newly synthesized GLUT4 into the insulin-responsive storage compartment is GGA dependent
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PubMed Central
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30 September 2017
Regulated membrane trafficking of the insulin-responsive glucose transporter 4 in adipocytes
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30 September 2017
Role of caveolin and caveolae in insulin signaling and diabetes
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30 September 2017
GLUT4 is retained by an intracellular cycle of vesicle formation and fusion with endosomes
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369215
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30 September 2017
Insulin induces phosphatidylinositol-3-phosphate formation through TC10 activation.
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PubMed Central
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30 September 2017
Push/pull mechanisms of GLUT4 traffic in muscle cells
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PubMed Central
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30 September 2017
Insulin-induced GLUT4 translocation involves protein kinase C-lambda-mediated functional coupling between Rab4 and the motor protein kinesin
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PubMed Central
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30 September 2017
Tomosyn interacts with the t-SNAREs syntaxin4 and SNAP23 and plays a role in insulin-stimulated GLUT4 translocation
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PubMed Central
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30 September 2017
The insulin-regulated aminopeptidase: a companion and regulator of GLUT4
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PubMed Central
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30 September 2017
Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation
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PubMed Central
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30 September 2017
GLUT4 recycles via a trans-Golgi network (TGN) subdomain enriched in Syntaxins 6 and 16 but not TGN38: involvement of an acidic targeting motif
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PubMed Central
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30 September 2017
GLUT4 retention in adipocytes requires two intracellular insulin-regulated transport steps
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PubMed Central
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30 September 2017
Regulated transport of the glucose transporter GLUT4
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PubMed Central
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30 September 2017
Exploring the whereabouts of GLUT4 in skeletal muscle (review).
1 reference
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PubMed Central
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30 September 2017
Insulin signaling pathways in time and space.
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PubMed Central
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30 September 2017
Global and societal implications of the diabetes epidemic
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369215
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30 September 2017
Insulin can regulate GLUT4 internalization by signaling to Rab5 and the motor protein dynein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369215
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30 September 2017
Activation of protein kinase C zeta induces serine phosphorylation of VAMP2 in the GLUT4 compartment and increases glucose transport in skeletal muscle
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369215
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30 September 2017
Insulin accelerates inter-endosomal GLUT4 traffic via phosphatidylinositol 3-kinase and protein kinase B.
1 reference
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PubMed Central
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30 September 2017
Hyperosmolarity reduces GLUT4 endocytosis and increases its exocytosis from a VAMP2-independent pool in l6 muscle cells
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369215
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30 September 2017
Perturbation of dynamin II with an amphiphysin SH3 domain increases GLUT4 glucose transporters at the plasma membrane in 3T3-L1 adipocytes. Dynamin II participates in GLUT4 endocytosis
1 reference
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PubMed Central
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30 September 2017
Syntaxin 4, VAMP2, and/or VAMP3/cellubrevin are functional target membrane and vesicle SNAP receptors for insulin-stimulated GLUT4 translocation in adipocytes
1 reference
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PubMed Central
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30 September 2017
Insulin-stimulated translocation of GLUT4 glucose transporters requires SNARE-complex proteins
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369215
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30 September 2017
The glucose transporter (GLUT-4) and vesicle-associated membrane protein-2 (VAMP-2) are segregated from recycling endosomes in insulin-sensitive cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369215
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30 September 2017
Immuno-localization of the insulin regulatable glucose transporter in brown adipose tissue of the rat
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369215
retrieved
30 September 2017
Full intracellular retention of GLUT4 requires AS160 Rab GTPase activating protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369215
retrieved
29 June 2018
Akt2 phosphorylates Synip to regulate docking and fusion of GLUT4-containing vesicles
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369215
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29 June 2018
Control of muscle glucose uptake: test of the rate-limiting step paradigm in conscious, unrestrained mice
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369215
retrieved
29 June 2018
Insulin stimulates the entry of GLUT4 into the endosomal recycling pathway by a quantal mechanism.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369215
retrieved
29 June 2018
Expression of a dominant interfering dynamin mutant in 3T3L1 adipocytes inhibits GLUT4 endocytosis without affecting insulin signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369215
retrieved
29 June 2018
Endocytosis of the glucose transporter GLUT4 is mediated by the GTPase dynamin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369215
retrieved
29 June 2018
Use of bismannose photolabel to elucidate insulin-regulated GLUT4 subcellular trafficking kinetics in rat adipose cells. Evidence that exocytosis is a critical site of hormone action
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369215
retrieved
29 June 2018
Insulin signaling meets vesicle traffic of GLUT4 at a plasma-membrane-activated fusion step.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369215
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22 September 2018
Insulin regulates the membrane arrival, fusion, and C-terminal unmasking of glucose transporter-4 via distinct phosphoinositides
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369215
retrieved
22 September 2018
Synip phosphorylation does not regulate insulin-stimulated GLUT4 translocation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369215
retrieved
22 September 2018
Akt activation is required at a late stage of insulin-induced GLUT4 translocation to the plasma membrane.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369215
retrieved
22 September 2018
Protein kinase B phosphorylation of PIKfyve regulates the trafficking of GLUT4 vesicles.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369215
retrieved
22 September 2018
Skeletal muscle cells and adipocytes differ in their reliance on TC10 and Rac for insulin-induced actin remodeling
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369215
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22 September 2018
Immunoelectron microscopic evidence that GLUT4 translocation explains the stimulation of glucose transport in isolated rat white adipose cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369215
retrieved
22 September 2018
Vesicle-associated membrane protein 2 plays a specific role in the insulin-dependent trafficking of the facilitative glucose transporter GLUT4 in 3T3-L1 adipocytes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369215
retrieved
22 September 2018
Phosphatidylinositol 3-kinase acts at an intracellular membrane site to enhance GLUT4 exocytosis in 3T3-L1 cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1369215
retrieved
22 September 2018
Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.EMBOR.7400584
retrieved
7 January 2021
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Identifiers
DOI
10.1038/SJ.EMBOR.7400584
1 reference
stated in
Europe PubMed Central
PMCID
1369215
retrieved
13 August 2017
PMCID
1369215
1 reference
stated in
Europe PubMed Central
PMCID
1369215
retrieved
13 August 2017
PubMed ID
16319959
1 reference
stated in
Europe PubMed Central
PMCID
1369215
retrieved
13 August 2017
ResearchGate publication ID
7448937
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