(Q36342850)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22988096%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

α-Synuclein disrupts stress signaling by inhibiting polo-like kinase Cdc5/Plk2 (English)

1 reference

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13 February 2020

1 reference

2

1 reference

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13 February 2020

Shile Huang

5

1 reference

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13 February 2020

author name string

Shaoxiao Wang

1

1 reference

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13 February 2020

Liang-Chun Liou

3

1 reference

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13 February 2020

Qun Ren

4

1 reference

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13 February 2020

Yan Luo

6

1 reference

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13 February 2020

Zhaojie Zhang

7

1 reference

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13 February 2020

Stephan N Witt

8

1 reference

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13 February 2020

language of work or name

English

0 references

publication date

17 September 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22988096%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

13 February 2020

published in

1 reference

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13 February 2020

volume

109

1 reference

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13 February 2020

issue

40

1 reference

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13 February 2020

page(s)

16119-16124

1 reference

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N-terminal deletion does not affect α-synuclein membrane binding, self-association and toxicity in human neuroblastoma cells, unlike yeast

13 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3479570

Gaucher disease glucocerebrosidase and α-synuclein form a bidirectional pathogenic loop in synucleinopathies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3479570

Requirement for Plk2 in orchestrated ras and rap signaling, homeostatic structural plasticity, and memory

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3479570

Defects in very long chain fatty acid synthesis enhance alpha-synuclein toxicity in a yeast model of Parkinson's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3479570

Phosphorylation of synucleins by members of the Polo-like kinase family

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3479570

Polo-like kinases: conservation and divergence in their functions and regulation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3479570

Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3479570

Polo-like kinase 2 (PLK2) phosphorylates alpha-synuclein at serine 129 in central nervous system

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3479570

Polo-like kinase Cdc5 controls the local activation of Rho1 to promote cytokinesis.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3479570

Cell wall integrity signaling in Saccharomyces cerevisiae

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3479570

The Ras superfamily at a glance

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3479570

Discovery of cercosporamide, a known antifungal natural product, as a selective Pkc1 kinase inhibitor through high-throughput screening

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3479570

Coupling morphogenesis to mitotic entry

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3479570

The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3479570

alpha-Synuclein locus triplication causes Parkinson's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3479570

Molecular Pathways of Neurodegeneration in Parkinson's Disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3479570

Regulation of the yeast Rlm1 transcription factor by the Mpk1 cell wall integrity MAP kinase.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3479570

Cellular response to oxidative stress: signaling for suicide and survival

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3479570

alpha-Synuclein affects the MAPK pathway and accelerates cell death

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3479570

Actin-latrunculin A structure and function. Differential modulation of actin-binding protein function by latrunculin A

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3479570

Plasma membrane localization is required for RGS4 function in Saccharomyces cerevisiae

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3479570

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3479570

Alpha-synuclein in Lewy bodies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3479570

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3479570

Phosphorylation of Ser-129 is the dominant pathological modification of alpha-synuclein in familial and sporadic Lewy body disease

30 September 2017

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1206286109

Targeted Protein Degradation and Synapse Remodeling by an Inducible Protein Kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1206286109

Yeast cells provide insight into alpha-synuclein biology and pathobiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1206286109

Mechanisms for concentrating Rho1 during cytokinesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1206286109

Induction of apoptosis by SB202190 through inhibition of p38beta mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1206286109

21 January 2018

Identifiers

DOI

10.1073/PNAS.1206286109

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22988096%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22988096%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

PubMed publication ID

22988096

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22988096%20AND%20SRC:MED&resulttype=core&format=json