(Q36343316)

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Middle East respiratory syndrome coronavirus ORF4b protein inhibits type I interferon production through both cytoplasmic and nuclear targets

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scholarly article

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Europe PubMed Central

13 August 2017

Middle East respiratory syndrome coronavirus ORF4b protein inhibits type I interferon production through both cytoplasmic and nuclear targets (English)

1 reference

Europe PubMed Central

13 August 2017

Middle East respiratory syndrome coronavirus

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0 references

1 reference

based on heuristic

inferred from title

Middle East respiratory syndrome

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based on heuristic

inferred from title

3

object named as

Na Zhu

1 reference

Europe PubMed Central

13 August 2017

author name string

Yang Yang

1

1 reference

Europe PubMed Central

13 August 2017

Fei Ye

2

1 reference

Europe PubMed Central

13 August 2017

Wenling Wang

4

1 reference

Europe PubMed Central

13 August 2017

Yao Deng

5

1 reference

Europe PubMed Central

13 August 2017

Zhengdong Zhao

6

1 reference

Europe PubMed Central

13 August 2017

Wenjie Tan

7

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Europe PubMed Central

13 August 2017

language of work or name

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publication date

3 December 2015

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Europe PubMed Central

13 August 2017

Scientific Reports

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Europe PubMed Central

13 August 2017

5

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Europe PubMed Central

13 August 2017

17554

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Europe PubMed Central

13 August 2017

copyright license

Creative Commons Attribution 4.0 International

1 December 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

https://scigraph.springernature.com/pub.10.1038/srep17554

0 references

Spread of MERS to South Korea and China

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4668369

30 September 2017

Crystal structure of the Middle East respiratory syndrome coronavirus (MERS-CoV) papain-like protease bound to ubiquitin facilitates targeted disruption of deubiquitinating activity to demonstrate its role in innate immune suppression

1 reference

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30 September 2017

Herpes Simplex Virus 1 (HSV-1) ICP22 protein directly interacts with cyclin-dependent kinase (CDK)9 to inhibit RNA polymerase II transcription elongation

1 reference

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30 September 2017

SARS-coronavirus open reading frame-9b suppresses innate immunity by targeting mitochondria and the MAVS/TRAF3/TRAF6 signalosome

1 reference

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30 September 2017

SARS coronavirus papain-like protease inhibits the type I interferon signaling pathway through interaction with the STING-TRAF3-TBK1 complex

1 reference

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30 September 2017

Middle east respiratory syndrome coronavirus 4a protein is a double-stranded RNA-binding protein that suppresses PACT-induced activation of RIG-I and MDA5 in the innate antiviral response.

1 reference

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30 September 2017

The ORF4b-encoded accessory proteins of Middle East respiratory syndrome coronavirus and two related bat coronaviruses localize to the nucleus and inhibit innate immune signalling

1 reference

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30 September 2017

Specific residues of PB2 and PA influenza virus polymerase subunits confer the ability for RNA polymerase II degradation and virus pathogenicity in mice

1 reference

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30 September 2017

Proteolytic processing, deubiquitinase and interferon antagonist activities of Middle East respiratory syndrome coronavirus papain-like protease

1 reference

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30 September 2017

The structural and accessory proteins M, ORF 4a, ORF 4b, and ORF 5 of Middle East respiratory syndrome coronavirus (MERS-CoV) are potent interferon antagonists

1 reference

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30 September 2017

Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4668369

30 September 2017

Middle East respiratory syndrome coronavirus accessory protein 4a is a type I interferon antagonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4668369

30 September 2017

Engineering a replication-competent, propagation-defective Middle East respiratory syndrome coronavirus as a vaccine candidate

1 reference

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30 September 2017

Interhuman transmissibility of Middle East respiratory syndrome coronavirus: estimation of pandemic risk.

1 reference

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30 September 2017

The influenza virus NS1 protein as a therapeutic target

1 reference

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30 September 2017

MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-α treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4668369

30 September 2017

Inhibition of novel β coronavirus replication by a combination of interferon-α2b and ribavirin

1 reference

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30 September 2017

Enterovirus 71 protease 2Apro targets MAVS to inhibit anti-viral type I interferon responses

1 reference

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30 September 2017

Tropism of and innate immune responses to the novel human betacoronavirus lineage C virus in human ex vivo respiratory organ cultures

1 reference

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30 September 2017

Human cell tropism and innate immune system interactions of human respiratory coronavirus EMC compared to those of severe acute respiratory syndrome coronavirus

1 reference

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30 September 2017

Recent advances in understanding viral evasion of type I interferon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4668369

30 September 2017

Hepatitis C virus NS2 protease inhibits host cell antiviral response by inhibiting IKKε and TBK1 functions

1 reference

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30 September 2017

Severe respiratory illness caused by a novel coronavirus, in a patient transferred to the United Kingdom from the Middle East, September 2012.

1 reference

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30 September 2017

Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia

1 reference

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30 September 2017

SARS coronavirus pathogenesis: host innate immune responses and viral antagonism of interferon

1 reference

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30 September 2017

A novel mechanism for the inhibition of interferon regulatory factor-3-dependent gene expression by human respiratory syncytial virus NS1 protein

1 reference

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30 September 2017

The 3C protein of enterovirus 71 inhibits retinoid acid-inducible gene I-mediated interferon regulatory factor 3 activation and type I interferon responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4668369

30 September 2017

Deubiquitinating and interferon antagonism activities of coronavirus papain-like proteases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4668369

30 September 2017

Influenza viruses control the vertebrate type I interferon system: factors, mechanisms, and consequences

1 reference

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30 September 2017

Attenuated strains of influenza A viruses do not induce degradation of RNA polymerase II.

1 reference

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30 September 2017

Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I

1 reference

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30 September 2017

Severe acute respiratory syndrome coronavirus M protein inhibits type I interferon production by impeding the formation of TRAF3.TANK.TBK1/IKKepsilon complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4668369

30 September 2017

Severe acute respiratory syndrome coronavirus papain-like protease ubiquitin-like domain and catalytic domain regulate antagonism of IRF3 and NF-kappaB signaling

1 reference

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30 September 2017

Ebola virus protein VP35 impairs the function of interferon regulatory factor-activating kinases IKKepsilon and TBK-1

1 reference

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30 September 2017

Mechanism of mda-5 Inhibition by paramyxovirus V proteins.

1 reference

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30 September 2017

Select paramyxoviral V proteins inhibit IRF3 activation by acting as alternative substrates for inhibitor of kappaB kinase epsilon (IKKe)/TBK1.

1 reference

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30 September 2017

Severe acute respiratory syndrome coronavirus nsp1 suppresses host gene expression, including that of type I interferon, in infected cells

1 reference

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30 September 2017

MDA5/RIG-I and virus recognition.

1 reference

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30 September 2017

A SAP30 complex inhibits IFN-beta expression in Rift Valley fever virus infected cells.

1 reference

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30 September 2017

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1 reference

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30 September 2017

Regulation of IRF-3-dependent innate immunity by the papain-like protease domain of the severe acute respiratory syndrome coronavirus

1 reference

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1 reference

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1 reference

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30 September 2017

Multiple anti-interferon actions of the influenza A virus NS1 protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4668369

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Herpes simplex virus immediate-early protein ICP22 triggers loss of serine 2-phosphorylated RNA polymerase II

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4668369

30 September 2017

Influenza virus infection causes specific degradation of the largest subunit of cellular RNA polymerase II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4668369

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Influenza virus targets the mRNA export machinery and the nuclear pore complex

1 reference

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Severe acute respiratory syndrome coronavirus open reading frame (ORF) 3b, ORF 6, and nucleocapsid proteins function as interferon antagonists

1 reference

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1 reference

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1 reference

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30 September 2017

ICP27 interacts with the C-terminal domain of RNA polymerase II and facilitates its recruitment to herpes simplex virus 1 transcription sites, where it undergoes proteasomal degradation during infection

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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The severe acute respiratory syndrome

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1 reference

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1 reference

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22 September 2018

Clusters of coronavirus cases put scientists on alert

1 reference

https://api.crossref.org/works/10.1038%2FSREP17554

21 January 2018

Identifiers

10.1038/SREP17554

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

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