Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q36346846)
Watch
English
Integrin β5 contributes to the tumorigenic potential of breast cancer cells through the Src-FAK and MEK-ERK signaling pathways.
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
3481019
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22824793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
title
Integrin β5 contributes to the tumorigenic potential of breast cancer cells through the Src-FAK and MEK-ERK signaling pathways
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3481019
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22824793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
main subject
breast cancer
1 reference
based on heuristic
inferred from title
author
Anna Bianchi-Smiraglia
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
3481019
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22824793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
Andrei Bakin
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
3481019
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22824793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
author name string
S Paesante
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
3481019
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22824793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
language of work or name
English
0 references
publication date
23 July 2012
1 reference
stated in
Europe PubMed Central
PMCID
3481019
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22824793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
published in
Oncogene
1 reference
stated in
Europe PubMed Central
PMCID
3481019
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22824793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
volume
32
1 reference
stated in
Europe PubMed Central
PMCID
3481019
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22824793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
page(s)
3049-3058
1 reference
stated in
Europe PubMed Central
PMCID
3481019
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22824793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
issue
25
1 reference
stated in
Europe PubMed Central
PMCID
3481019
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22824793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
exact match
https://scigraph.springernature.com/pub.10.1038/onc.2012.320
0 references
cites work
Tenascin-C enhances crosstalk signaling of integrin αvβ3/PDGFR-β complex by SRC recruitment promoting PDGF-induced proliferation and migration in smooth muscle cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
Microarrays in the 2010s: the contribution of microarray-based gene expression profiling to breast cancer classification, prognostication and prediction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
Present and future evolution of advanced breast cancer therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
Regulation of mRNA translation and stability by microRNAs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
Role of β5-integrin in epithelial-mesenchymal transition in response to TGF-β.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
Genome remodelling in a basal-like breast cancer metastasis and xenograft
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
Integrins in cancer: biological implications and therapeutic opportunities
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
Focal adhesion kinase: a prominent determinant in breast cancer initiation, progression and metastasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
Alphavbeta3 and alphavbeta5 integrins control glioma cell response to ionising radiation through ILK and RhoB.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
Stromal gene expression predicts clinical outcome in breast cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
TAK1 is required for TGF-beta 1-mediated regulation of matrix metalloproteinase-9 and metastasis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
Vascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internally expressed VEGFR1/FLT1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
The integrins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
Clonogenic assay of cells in vitro.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
Cellular characterization of a novel focal adhesion kinase inhibitor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
Drug insight: VEGF as a therapeutic target for breast cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
Cancer statistics, 2007
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
ALK5 promotes tumor angiogenesis by upregulating matrix metalloproteinase-9 in tumor cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
Intrinsic FAK activity and Y925 phosphorylation facilitate an angiogenic switch in tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
X chromosomal abnormalities in basal-like human breast cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
The role of focal-adhesion kinase in cancer - a new therapeutic opportunity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
Identification of Src-specific phosphorylation site on focal adhesion kinase: dissection of the role of Src SH2 and catalytic functions and their consequences for tumor cell behavior
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
A critical role of tropomyosins in TGF-beta regulation of the actin cytoskeleton and cell motility in epithelial cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
Differential alphav integrin-mediated Ras-ERK signaling during two pathways of angiogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
P21-activated kinase 4 interacts with integrin alpha v beta 5 and regulates alpha v beta 5-mediated cell migration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
Src-mediated coupling of focal adhesion kinase to integrin alpha(v)beta5 in vascular endothelial growth factor signaling.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
Altered adhesion properties and alphav integrin expression in a cisplatin-resistant human ovarian carcinoma cell line.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
Integrin-induced epidermal growth factor (EGF) receptor activation requires c-Src and p130Cas and leads to phosphorylation of specific EGF receptor tyrosines
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
Complexes of tetraspanins with integrins: more than meets the eye
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
Src mediates stimulation by vascular endothelial growth factor of the phosphorylation of focal adhesion kinase at tyrosine 861, and migration and anti-apoptosis in endothelial cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
Anoikis mechanisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
Paxillin and focal adhesion signalling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
The Hallmarks of Cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
Expression of alphav integrins and vitronectin receptor identity in breast cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
Integrin-mediated activation of MAP kinase is independent of FAK: evidence for dual integrin signaling pathways in fibroblasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
Involvement of extracellular signal-regulated kinase 2 and stress-activated protein kinase/Jun N-terminal kinase activation by transforming growth factor beta in the negative growth control of breast cancer cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
Relationship among guanine nucleotide exchange, GTP hydrolysis, and transforming potential of mutated ras proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
30 September 2017
Specific cross-talk between epidermal growth factor receptor and integrin alphavbeta5 promotes carcinoma cell invasion and metastasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
29 June 2018
Autocrine transforming growth factor-beta signaling mediates Smad-independent motility in human cancer cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
29 June 2018
Extracellular signal-regulated kinase and the small GTP-binding protein, Rac, contribute to the effects of transforming growth factor-beta1 on gene expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
29 June 2018
Discovery of N-(2-chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
22 September 2018
Phosphorylation of focal adhesion kinase at tyrosine 861 is crucial for Ras transformation of fibroblasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
22 September 2018
Human breast cancer MDA-MB-231 cells fail to express the neurofibromin protein, lack its type I mRNA isoform and show accumulation of P-MAPK and activated Ras.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3481019
retrieved
22 September 2018
Clinical significance of high focal adhesion kinase gene copy number and overexpression in invasive breast cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FONC.2012.320
retrieved
31 March 2020
Identifiers
DOI
10.1038/ONC.2012.320
1 reference
stated in
Europe PubMed Central
PMCID
3481019
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22824793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
PMCID
3481019
1 reference
stated in
Europe PubMed Central
PMCID
3481019
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22824793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
PubMed ID
22824793
1 reference
stated in
Europe PubMed Central
PMCID
3481019
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22824793%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 February 2020
ResearchGate publication ID
229552738
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
