(Q36355369)

13 August 2017

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title

Role of endogenous benzodiazepine ligands and their GABA-A--associated receptors in hepatic encephalopathy (English)

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13 August 2017

2

Roger F Butterworth

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13 August 2017

Samir Ahboucha

1

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13 August 2017

publication date

1 December 2005

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13 August 2017

published in

Metabolic Brain Disease

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13 August 2017

volume

20

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13 August 2017

issue

4

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13 August 2017

page(s)

425-437

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Supersensitivity of Benzodiazepine Receptors in Hepatic Encephalopathy Due to Fulminant Hepatic Failure in the Rat: Reversal by a Benzodiazepine Antagonist

13 August 2017

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11011-005-7928-Y

Regional Distribution and Kinetics of Three Sites on the GABAA Receptor: Lack of Effect of Portacaval Shunting

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11011-005-7928-Y

Differential responsiveness of cerebellar Purkinje neurons to GABA and benzodiazepine receptor ligands in an animal model of hepatic encephalopathy

21 January 2018

1 reference

12 December 2020

Flumazenil vs. placebo in hepatic encephalopathy in patients with cirrhosis: a meta-analysis

1 reference

12 December 2020

Endogenous benzodiazepine receptor ligands in human and animal hepatic encephalopathy.

1 reference

12 December 2020

Elevated brain concentrations of 1,4-benzodiazepines in fulminant hepatic failure

1 reference

12 December 2020

Treatment of hepatic encephalopathy (HE) with the benzodiazepine antagonist flumazenil: a pilot study

1 reference

12 December 2020

Hepatic encephalopathy in rats with thioacetamide-induced acute liver failure is not mediated by endogenous benzodiazepines

1 reference

12 December 2020

Normal coupling of brain benzodiazepine and neurosteroid modulatory sites on the GABA-A receptor complex in human hepatic encephalopathy

1 reference

12 December 2020

Plasma GABA, GABA-like activity and the brain GABA-benzodiazepine receptor complex in rats with chronic hepatic encephalopathy

1 reference

12 December 2020

Pharmacokinetics of benzodiazepine antagonist Ro 15-1788 in cirrhotic patients with moderate or severe liver dysfunction

1 reference

12 December 2020

Potential mechanisms of enhanced GABA-mediated inhibitory neurotransmission in liver failure

1 reference

12 December 2020

Flumazenil for hepatic encephalopathy grade III and IVa in patients with cirrhosis: an Italian multicenter double-blind, placebo-controlled, cross-over study

1 reference

12 December 2020

Combination treatment of hepatic encephalopathy due to thioacetamide-induced fulminant hepatic failure in the rat with benzodiazepine and opioid receptor antagonists

1 reference

12 December 2020

Affinities and densities of high-affinity [3H]muscimol (GABA-A) binding sites and of central benzodiazepine receptors are unchanged in autopsied brain tissue from cirrhotic patients with hepatic encephalopathy.

1 reference

12 December 2020

"Endogenous" benzodiazepine activity in body fluids of patients with hepatic encephalopathy

1 reference

12 December 2020

Ro 15-4513: partial inverse agonism at the BZR and interaction with ethanol.

1 reference

12 December 2020

Selective antagonists of benzodiazepines

1 reference

12 December 2020

Beneficial effect of pharmacological modulation of the GABAA-benzodiazepine receptor on hepatic encephalopathy in the rat: comparison with uremic encephalopathy

1 reference

12 December 2020

Cerebral uptake of benzodiazepine measured by positron emission tomography in hepatic encephalopathy

1 reference

12 December 2020

Ammonia and endogenous benzodiazepine-like compounds in the pathogenesis of hepatic encephalopathy

1 reference

12 December 2020

The effects of benzodiazepine-receptor antagonists and partial inverse agonists on acute hepatic encephalopathy in the rat

1 reference

12 December 2020

Increased benzodiazepine-like activity is neither necessary nor sufficient to explain acute hepatic encephalopathy in the thioacetamide-treated rat.

1 reference

12 December 2020

Cerebral benzodiazepine receptor binding in vivo in patients with recurrent hepatic encephalopathy

1 reference

12 December 2020

Plasma concentrations of endogenous benzodiazepine-receptor ligands in patients with hepatic encephalopathy: a comparative study

1 reference

12 December 2020

Amelioration of hepatic encephalopathy by pharmacologic antagonism of the GABAA-benzodiazepine receptor complex in a rabbit model of fulminant hepatic failure

1 reference

12 December 2020

Autoradiographic analysis of GABA-benzodiazepine receptors in an animal model of acute hepatic encephalopathy

1 reference

12 December 2020

Successful long-term treatment of portal-systemic encephalopathy by the benzodiazepine antagonist flumazenil

1 reference

12 December 2020

Increased availability of central benzodiazepine receptors in patients with chronic hepatic encephalopathy and alcohol related cirrhosis

1 reference

12 December 2020

Benzodiazepine receptor ligands are elevated in an animal model of hepatic encephalopathy: relationship between brain concentration and severity of encephalopathy.

1 reference

12 December 2020

Flumazenil does not improve hepatic encephalopathy associated with acute ischemic liver failure in the rabbit.

1 reference

12 December 2020

Reversal of hepatic coma by benzodiazepine antagonist (Ro 15-1788)

1 reference

12 December 2020

Improvement of chronic hepatic encephalopathy in dogs by the benzodiazepine-receptor partial inverse agonist sarmazenil, but not by the antagonist flumazenil

1 reference

12 December 2020

Evaluation of the efficacy and safety of flumazenil in the treatment of portal systemic encephalopathy: a double blind, randomised, placebo controlled multicentre study

1 reference

12 December 2020

Improvement of hepatic encephalopathy treated with flumazenil

1 reference

12 December 2020

Flumazenil therapy for hepatic encephalopathy in cirrhotic patients: a double-blind pragmatic randomized, placebo study

1 reference

12 December 2020

Amino acid neurotransmitter receptor changes in cerebral cortex in alcoholism: effect of cirrhosis of the liver

1 reference

12 December 2020

The involvement of ammonia with the mechanisms that enhance GABA-ergic neurotransmission in hepatic failure

1 reference

12 December 2020

Effect of flumazenil on the electroencephalogram of patients with portosystemic encephalopathy. Results of a double blind, randomised, placebo-controlled multicentre trial

1 reference

12 December 2020

Plasma and CSF benzodiazepine receptor ligand concentrations in cirrhotic patients with hepatic encephalopathy: relationship to severity of encephalopathy and to pharmaceutical benzodiazepine intake

1 reference

12 December 2020

Diazepam and N-desmethyldiazepam are found in rat brain and adrenal and may be of plant origin

1 reference

12 December 2020

Increased brain concentrations of a neuroinhibitory steroid in human hepatic encephalopathy

1 reference

12 December 2020

gamma-Aminobutyric acid(A) neurotransmission and cerebral ischemia

1 reference

12 December 2020

Brain concentrations of benzodiazepines are elevated in an animal model of hepatic encephalopathy

1 reference

12 December 2020

Flumazenil therapy for hepatic encephalopathy. A double-blind cross over study

1 reference

12 December 2020

Differential effects of ammonia on the benzodiazepine modulatory site on the GABA-A receptor complex of human brain

1 reference

12 December 2020

Hepatic encephalopathy: An update of pathophysiologic mechanisms

1 reference

12 December 2020

A benzodiazepine antagonist does not alter the course of hepatic encephalopathy or neural gamma-aminobutyric acid (GABA) binding

1 reference

12 December 2020

Increased brain concentrations of endogenous (non-benzodiazepine) GABA-A receptor ligands in human hepatic encephalopathy

1 reference

12 December 2020

Hepatic encephalopathy in cirrhotic and portacaval shunted dogs: lack of changes in brain GABA uptake, brain GABA levels, brain glutamic acid decarboxylase activity and brain postsynaptic GABA receptors

1 reference

12 December 2020

Reversal of the behavioral and electrophysiological abnormalities of an animal model of hepatic encephalopathy by benzodiazepine receptor ligands

1 reference

12 December 2020

Pathophysiology of hepatic encephalopathy: a new look at GABA from the molecular standpoint

1 reference

12 December 2020

Modulation of ligand binding to components of the GABAA receptor complex by ammonia: implications for the pathogenesis of hyperammonemic syndromes

1 reference

12 December 2020

Gamma-aminobutyric acid and benzodiazepine receptors in an animal model of fulminant hepatic failure

1 reference

12 December 2020

Flumazenil in cirrhotic patients in hepatic coma: a randomized double-blind placebo-controlled crossover trial

1 reference

12 December 2020

10.1007/S11011-005-7928-Y

Identifiers

DOI

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13 August 2017

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