(Q36368573)

13 August 2017

Error-prone candidates vie for somatic mutation (English)

1 reference

13 August 2017

V Poltoratsky

1

1 reference

13 August 2017

M F Goodman

series ordinal

2

1 reference

13 August 2017

M D Scharff

series ordinal

3

1 reference

13 August 2017

language of work or name

English

0 references

publication date

1 November 2000

1 reference

Journal of Experimental Medicine

13 August 2017

1 reference

13 August 2017

192

1 reference

13 August 2017

F27-30

1 reference

13 August 2017

10

1 reference

The expanding polymerase universe

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193189

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193189

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193189

Eukaryotic polymerases iota and zeta act sequentially to bypass DNA lesions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193189

poliota, a remarkably error-prone human DNA polymerase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193189

DNA polymerase mu (Pol mu), homologous to TdT, could act as a DNA mutator in eukaryotic cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193189

Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193189

A human REV7 homolog that interacts with the polymerase zeta catalytic subunit hREV3 and the spindle assembly checkpoint protein hMAD2

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193189

Mice reconstituted with DNA polymerase beta-deficient fetal liver cells are able to mount a T cell-dependent immune response and mutate their Ig genes normally

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193189

Bridging the gap: a family of novel DNA polymerases that replicate faulty DNA.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193189

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193189

Somatic hypermutation and the three R's: repair, replication and recombination

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193189

TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193189

BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193189

Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193189

Both DNA strands of antibody genes are hypermutation targets

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193189

A human homolog of the Saccharomyces cerevisiae REV3 gene, which encodes the catalytic subunit of DNA polymerase zeta

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193189

The role of DNA repair in somatic hypermutation of immunoglobulin genes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193189

The targeting of somatic hypermutation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193189

Thymine-thymine dimer bypass by yeast DNA polymerase zeta

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193189

Mechanism of antigen-driven somatic hypermutation of rearranged immunoglobulin V(D)J genes in the mouse

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193189

Roles of E. coli DNA polymerases IV and V in lesion-targeted and untargeted SOS mutagenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193189

Evolution of somatic hypermutation and gene conversion in adaptive immunity

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193189

Mismatch repair co-opted by hypermutation.

28 June 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.192.10.F27

Somatic hypermutation in the absence of DNA-dependent protein kinase catalytic subunit (DNA-PK(cs)) or recombination-activating gene (RAG)1 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.192.10.F27

Deficiency in Msh2 affects the efficiency and local sequence specificity of immunoglobulin class-switch recombination: parallels with somatic hypermutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.192.10.F27

Developmental control of cell cycle regulators: a fly's perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.192.10.F27

Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.192.10.F27

Origin of Antibody Variation

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.192.10.F27

Amino acid insertions and deletions contribute to diversify the human Ig repertoire

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.192.10.F27

Progress in understanding the mechanism and consequences of somatic hypermutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.192.10.F27

Somatic hypermutation, transcription, and DNA mismatch repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.192.10.F27

Probing immunoglobulin gene hypermutation with microsatellites suggests a nonreplicative short patch DNA synthesis process

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.192.10.F27

21 January 2018

Identifiers

DOI

10.1084/JEM.192.10.F27

1 reference

13 August 2017

1 reference

13 August 2017

1 reference