(Q36369844)

13 August 2017

Restrictions limiting the generation of DNA double strand breaks during chromosomal V(D)J recombination (English)

1 reference

13 August 2017

Robert E Tillman

1

1 reference

13 August 2017

Andrea L Wooley

2

1 reference

13 August 2017

Maureen M Hughes

3

1 reference

13 August 2017

Tara D Wehrly

4

1 reference

13 August 2017

Wojciech Swat

5

1 reference

13 August 2017

Barry P Sleckman

6

1 reference

13 August 2017

language of work or name

English

0 references

publication date

1 February 2002

1 reference

Journal of Experimental Medicine

13 August 2017

1 reference

13 August 2017

195

1 reference

13 August 2017

3

1 reference

13 August 2017

309-316

1 reference

Factors and forces controlling V(D)J recombination

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Mechanisms that direct ordered assembly of T cell receptor beta locus V, D, and J gene segments

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Recombination signal sequences restrict chromosomal V(D)J recombination beyond the 12/23 rule.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Critical role for Atm in suppressing V(D)J recombination-driven thymic lymphoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Intermolecular V(D)J recombination is prohibited specifically at the joining step

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Identification of genes involved in repair of DNA double-strand breaks in mammalian cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Enhancer control of V(D)J recombination at the TCRbeta locus: differential effects on DNA cleavage and joining

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Assembly of a 12/23 paired signal complex: a critical control point in V(D)J recombination

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Enhancer control of local accessibility to V(D)J recombinase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Ku86 is not required for protection of signal ends or for formation of nonstandard V(D)J recombination products

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

RAG1 and RAG2 form a stable postcleavage synaptic complex with DNA containing signal ends in V(D)J recombination

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

The 12/23 rule is enforced at the cleavage step of V(D)J recombination in vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

A stable RAG1-RAG2-DNA complex that is active in V(D)J cleavage

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Pleiotropic defects in ataxia-telangiectasia protein-deficient mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Accessibility control of antigen-receptor variable-region gene assembly: role of cis-acting elements

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Cell type-specific chromatin structure determines the targeting of V(D)J recombinase activity in vitro

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Initiation of V(D)J recombination in vitro obeying the 12/23 rule

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Initiation of V(D)J recombination in a cell-free system.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

V(D)J recombination and double-strand break repair

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Somatic generation of antibody diversity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Ordered rearrangement of immunoglobulin heavy chain variable region segments

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Cutting and closing without recombination in V(D)J joining

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

V(D)J recombination: molecular biology and regulation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Interallelic V(D)J trans-rearrangement within the beta T cell receptor gene is infrequent and occurs preferentially during attempted D beta to J beta joining

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Recent advances in understanding V(D)J recombination.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

DNA transposition by the RAG1 and RAG2 proteins: a possible source of oncogenic translocations.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193590

Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps.

28 June 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20011803

Rejoining of DNA by the RAG1 and RAG2 proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20011803

Novel strand exchanges in V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20011803

Function of the TCR alpha enhancer in alphabeta and gammadelta T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20011803

Double-strand signal sequence breaks in V(D)J recombination are blunt, 5'-phosphorylated, RAG-dependent, and cell cycle regulated

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20011803

V(D)J recombination in Ku86-deficient mice: distinct effects on coding, signal, and hybrid joint formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20011803

Intermolecular V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20011803

21 January 2018

Identifiers

DOI

10.1084/JEM.20011803

1 reference

13 August 2017

1 reference

13 August 2017

1 reference