(Q36371054)

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The lectin-like domain of thrombomodulin confers protection from neutrophil-mediated tissue damage by suppressing adhesion molecule expression via nuclear factor kappaB and mitogen-activated protein kinase pathways

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scholarly article

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Europe PubMed Central

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12 November 2019

The lectin-like domain of thrombomodulin confers protection from neutrophil-mediated tissue damage by suppressing adhesion molecule expression via nuclear factor kappaB and mitogen-activated protein kinase pathways (English)

1 reference

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12 November 2019

Edward M. Conway

1

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12 November 2019

Peter W Hellings

9

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12 November 2019

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12 November 2019

Jeffrey I. Weitz

7

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Jeffrey I Weitz

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12 November 2019

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Marlies Van de Wouwer

2

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12 November 2019

Saskia Pollefeyt

3

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12 November 2019

Kerstin Jurk

4

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12 November 2019

Hugo Van Aken

5

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12 November 2019

Astrid De Vriese

6

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12 November 2019

Hartmut Weiler

8

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12 November 2019

Jean-Marc Herbert

11

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12 November 2019

Désiré Collen

12

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12 November 2019

Gregor Theilmeier

13

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12 November 2019

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1 September 2002

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12 November 2019

Journal of Experimental Medicine

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12 November 2019

196

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12 November 2019

565-577

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12 November 2019

5

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12 November 2019

Down-regulation of endothelial expression of endothelial cell protein C receptor and thrombomodulin in coronary atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

30 September 2017

Endothelial cells, megakaryoblasts, platelets and alveolar epithelial cells express abundant levels of the mouse AA4 antigen, a C-type lectin-like receptor involved in homing activities and innate immune host defense

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

30 September 2017

Protein C anticoagulant pathway and its role in controlling microvascular thrombosis and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

30 September 2017

Efficacy and safety of recombinant human activated protein C for severe sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

30 September 2017

Molecular and cellular properties of the rat AA4 antigen, a C-type lectin-like receptor with structural homology to thrombomodulin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

30 September 2017

Intercellular adhesion molecule-1 (ICAM-1) expression and cell signaling cascades

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

30 September 2017

The role of neutrophils in myocardial ischemia-reperfusion injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

30 September 2017

C-type lectins and galectins mediate innate and adaptive immune functions: their roles in the complement activation pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

30 September 2017

L-selectin interactions with novel mono- and multisulfated Lewisx sequences in comparison with the potent ligand 3'-sulfated Lewisa.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

30 September 2017

Structure-function analyses of thrombomodulin by gene-targeting in mice: the cytoplasmic domain is not required for normal fetal development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

30 September 2017

Integrins take partners: cross-talk between integrins and other membrane receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

30 September 2017

Resistance to endotoxic shock and reduced neutrophil migration in mice deficient for the Src-family kinases Hck and Fgr

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

30 September 2017

A targeted point mutation in thrombomodulin generates viable mice with a prethrombotic state

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

30 September 2017

Activation of thrombin-activable fibrinolysis inhibitor requires epidermal growth factor-like domain 3 of thrombomodulin and is inhibited competitively by protein C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

30 September 2017

Thrombomodulin modulates growth of tumor cells independent of its anticoagulant activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

30 September 2017

Urinary thrombomodulin, its isolation and characterization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

30 September 2017

Oncogenes in the study of endothelial cell growth and differentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

30 September 2017

Two distinct classes of carbohydrate-recognition domains in animal lectins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

30 September 2017

Tumor necrosis factor suppresses transcription of the thrombomodulin gene in endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

30 September 2017

Oxidation of a specific methionine in thrombomodulin by activated neutrophil products blocks cofactor activity. A potential rapid mechanism for modulation of coagulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

30 September 2017

Selectins and mechanisms of signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

28 June 2018

Thrombomodulin gene mutations associated with myocardial infarction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

28 June 2018

Measurement of Cutaneous Inflammation: Estimation of Neutrophil Content with an Enzyme Marker

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

28 June 2018

Early phase acute myocardial infarct size quantification: Validation of the triphenyl tetrazolium chloride tissue enzyme staining technique

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

28 June 2018

Modulation of endothelial cell hemostatic properties by tumor necrosis factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

28 June 2018

Plasma thrombomodulin in health and diseases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

28 June 2018

Presence and function of chondroitin-4-sulfate on recombinant human soluble thrombomodulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

28 June 2018

Thrombomodulin expression by human blood monocytes and by human synovial tissue lining macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

28 June 2018

Regulatory mechanisms for thrombomodulin expression in human umbilical vein endothelial cells in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

28 June 2018

An ultrastructural study of thrombomodulin endocytosis: internalization occurs via clathrin-coated and non-coated pits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

28 June 2018

Gene expression profile of antithrombotic protein c defines new mechanisms modulating inflammation and apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

21 September 2018

The alpha 4 beta 1 (very late antigen (VLA)-4, CD49d/CD29) and alpha 5 beta 1 (VLA-5, CD49e/CD29) integrins mediate beta 2 (CD11/CD18) integrin-independent neutrophil recruitment to endotoxin-induced lung inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

21 September 2018

Thrombomodulin Ala455Val polymorphism and risk of coronary heart disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

21 September 2018

Lymphatic endothelial tumors induced by intraperitoneal injection of incomplete Freund's adjuvant.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

21 September 2018

A mutation in the thrombomodulin gene, 127G to A coding for Ala25Thr, and the risk of myocardial infarction in men.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

21 September 2018

Maternally expressed PGK-Cre transgene as a tool for early and uniform activation of the Cre site-specific recombinase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

21 September 2018

The shape of thrombomodulin and interactions with thrombin as determined by electron microscopy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

21 September 2018

Myocardial ischemia and reperfusion: a murine model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193995

21 September 2018

Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1.

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20020077

21 January 2018

Characterization of a mouse model for thrombomodulin deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of alpha4 integrin and VCAM-1 in CD18-independent neutrophil migration across mouse cardiac endothelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The amino-terminal domain of thrombomodulin and pancreatic stone protein are homologous with lectins

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitation of a murine lung endothelial cell protein, P112, with a double monoclonal antibody assay

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A domain composed of epidermal growth factor-like structures of human thrombomodulin is essential for thrombin binding and for protein C activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human neutrophils synthesize thrombomodulin that does not promote thrombin-dependent protein C activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic value and clinicopathological correlation of thrombomodulin in squamous cell carcinoma of the human lung

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and characterization of a thrombomodulin gene mutation coding for an elongated protein with reduced expression in a kindred with myocardial infarction

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective effect of human urinary thrombomodulin on ischemia- reperfusion injury in the canine liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of endothelial cells from murine tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leukocyte and endothelial cell adhesion molecules in a chronic murine model of myocardial reperfusion injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of invasion and experimental metastasis of murine melanoma cells by human soluble thrombomodulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombomodulin gene defects in families with thromboembolic disease--a report on four families

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble thrombomodulin as a predictor of incident coronary heart disease and symptomless carotid artery atherosclerosis in the Atherosclerosis Risk in Communities (ARIC) Study: a case-cohort study

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circulating activated platelets assist THP-1 monocytoid/endothelial cell interaction under shear stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A sensitive and facile assay for the measurement of activated protein C activity levels in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/12208873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1084/JEM.20020077

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12208873%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12208873%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12208873%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

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