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IκB kinase ε phosphorylates TRAF2 to promote mammary epithelial cell transformation
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Europe PubMed Central
PMCID
3497603
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23007157%20AND%20SRC:MED&resulttype=core&format=json
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9 March 2020
title
IκB kinase ε phosphorylates TRAF2 to promote mammary epithelial cell transformation
(English)
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Europe PubMed Central
PMCID
3497603
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23007157%20AND%20SRC:MED&resulttype=core&format=json
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9 March 2020
main subject
phosphorylation
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author
Alicia Y Zhou
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2
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Europe PubMed Central
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3497603
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23007157%20AND%20SRC:MED&resulttype=core&format=json
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9 March 2020
Elgene Lim
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4
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3497603
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23007157%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
William C Hahn
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6
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William C Hahn
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3497603
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9 March 2020
author name string
Rhine R Shen
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1
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3497603
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9 March 2020
Eejung Kim
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3
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Europe PubMed Central
PMCID
3497603
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23007157%20AND%20SRC:MED&resulttype=core&format=json
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9 March 2020
Hasem Habelhah
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5
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3497603
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9 March 2020
language of work or name
English
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publication date
24 September 2012
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3497603
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9 March 2020
published in
Molecular and Cellular Biology
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3497603
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9 March 2020
volume
32
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9 March 2020
issue
23
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3497603
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23007157%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
page(s)
4756-4768
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3497603
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23007157%20AND%20SRC:MED&resulttype=core&format=json
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9 March 2020
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11 June 2022
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https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3497603/fullTextXML
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cites work
TRAF2 phosphorylation promotes NF-κB-dependent gene expression and inhibits oxidative stress-induced cell death
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497603
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30 September 2017
IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer
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30 September 2017
Requirement for NF-kappaB signalling in a mouse model of lung adenocarcinoma
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497603
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30 September 2017
TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (tnf) to efficiently activate nf-{kappa}b and to prevent tnf-induced apoptosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497603
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30 September 2017
Phosphorylation of the tumor suppressor CYLD by the breast cancer oncogene IKKepsilon promotes cell transformation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497603
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30 September 2017
Mutations of multiple genes cause deregulation of NF-kappaB in diffuse large B-cell lymphoma.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497603
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30 September 2017
The NF-{kappa}B negative regulator TNFAIP3 (A20) is inactivated by somatic mutations and genomic deletions in marginal zone lymphomas.
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30 September 2017
PKC phosphorylation of TRAF2 mediates IKKalpha/beta recruitment and K63-linked polyubiquitination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497603
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30 September 2017
TRAF2 phosphorylation modulates tumor necrosis factor alpha-induced gene expression and cell resistance to apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497603
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30 September 2017
New regulators of NF-kappaB in inflammation
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497603
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30 September 2017
Deubiquitylation and regulation of the immune response
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497603
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30 September 2017
Are the IKKs and IKK-related kinases TBK1 and IKK-epsilon similarly activated?
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497603
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30 September 2017
Oncogenic CARD11 mutations in human diffuse large B cell lymphoma
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497603
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30 September 2017
Physiological roles and mechanisms of signaling by TRAF2 and TRAF5.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497603
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30 September 2017
Integrative genomic approaches identify IKBKE as a breast cancer oncogene
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497603
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30 September 2017
Integrating cell-signalling pathways with NF-kappaB and IKK function
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497603
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30 September 2017
Nuclear factor-kappaB in cancer development and progression
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497603
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30 September 2017
NF-kappaB: linking inflammation and immunity to cancer development and progression
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497603
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30 September 2017
Ubiquitin signalling in the NF-kappaB pathway
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497603
retrieved
30 September 2017
Regulation of the deubiquitinating enzyme CYLD by IkappaB kinase gamma-dependent phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497603
retrieved
30 September 2017
TNF-alpha induced c-IAP1/TRAF2 complex translocation to a Ubc6-containing compartment and TRAF2 ubiquitination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497603
retrieved
30 September 2017
A pervasive role of ubiquitin conjugation in activation and termination of IkappaB kinase pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497603
retrieved
30 September 2017
A rapid method for determining protein kinase phosphorylation specificity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497603
retrieved
30 September 2017
The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497603
retrieved
30 September 2017
NF-kappaB functions as a tumour promoter in inflammation-associated cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497603
retrieved
30 September 2017
IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497603
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30 September 2017
Ubiquitination and translocation of TRAF2 is required for activation of JNK but not of p38 or NF-kappaB.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497603
retrieved
30 September 2017
The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497603
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30 September 2017
Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497603
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30 September 2017
CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497603
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30 September 2017
IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497603
retrieved
30 September 2017
Tumor necrosis factor (TNF)-induced germinal center kinase-related (GCKR) and stress-activated protein kinase (SAPK) activation depends upon the E2/E3 complex Ubc13-Uev1A/TNF receptor-associated factor 2 (TRAF2).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497603
retrieved
30 September 2017
NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497603
retrieved
30 September 2017
TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497603
retrieved
30 September 2017
Phosphorylation of TRAF2 within its RING domain inhibits stress-induced cell death by promoting IKK and suppressing JNK activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3497603
retrieved
21 September 2018
Identifiers
DOI
10.1128/MCB.00468-12
1 reference
stated in
Europe PubMed Central
PMCID
3497603
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23007157%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
PMCID
3497603
1 reference
stated in
Europe PubMed Central
PMCID
3497603
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23007157%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
PubMed ID
23007157
1 reference
stated in
Europe PubMed Central
PMCID
3497603
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23007157%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
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