(Q36399039)

English

Differential efficacy of caspase inhibitors on apoptosis markers during sepsis in rats and implication for fractional inhibition requirements for therapeutics

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Differential efficacy of caspase inhibitors on apoptosis markers during sepsis in rats and implication for fractional inhibition requirements for therapeutics (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

0 references

apoptotic process

0 references

Nathalie Méthot

1

object named as

Nathalie Méthot

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

7

object named as

Yongxin Han

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

8

object named as

John Colucci

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

author name string

JingQi Huang

2

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Nathalie Coulombe

3

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

John P Vaillancourt

4

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Dita Rasper

5

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

John Tam

6

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Robert Zamboni

9

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Steven Xanthoudakis

10

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Sylvie Toulmond

11

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Donald W Nicholson

12

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Sophie Roy

13

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

language of work or name

0 references

publication date

12 January 2004

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Journal of Experimental Medicine

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

199

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

2

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

199-207

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Mechanisms of caspase activation and inhibition during apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211770

30 September 2017

Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211770

30 September 2017

Direct cleavage of the human DNA fragmentation factor-45 by granzyme B induces caspase-activated DNase release and DNA fragmentation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211770

30 September 2017

From bench to clinic with apoptosis-based therapeutic agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211770

30 September 2017

Characterization of the rat DNA fragmentation factor 35/Inhibitor of caspase-activated DNase (Short form). The endogenous inhibitor of caspase-dependent DNA fragmentation in neuronal apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211770

30 September 2017

An auxiliary mode of apoptotic DNA fragmentation provided by phagocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211770

30 September 2017

Prevention of lymphocyte cell death in sepsis improves survival in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211770

30 September 2017

Caspase structure, proteolytic substrates, and function during apoptotic cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211770

30 September 2017

Overexpression of Bcl-2 in transgenic mice decreases apoptosis and improves survival in sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211770

30 September 2017

Cleavage of DFF-45/ICAD by multiple caspases is essential for its function during apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211770

30 September 2017

Caspases: enemies within

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211770

30 September 2017

The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211770

30 September 2017

Caspase-3 is required for alpha-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211770

30 September 2017

Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211770

30 September 2017

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211770

30 September 2017

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211770

30 September 2017

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211770

30 September 2017

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211770

30 September 2017

Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211770

30 September 2017

A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211770

30 September 2017

The calmodulin-binding site in alpha-fodrin is near the calcium-dependent protease-I cleavage site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211770

30 September 2017

Proteolysis of fodrin (non-erythroid spectrin) during apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211770

30 September 2017

Determinants of the nuclear localization of the heterodimeric DNA fragmentation factor (ICAD/CAD).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211770

28 June 2018

Caspase-3 is the primary activator of apoptotic DNA fragmentation via DNA fragmentation factor-45/inhibitor of caspase-activated DNase inactivation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211770

28 June 2018

Selective, reversible caspase-3 inhibitor is neuroprotective and reveals distinct pathways of cell death after neonatal hypoxic-ischemic brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211770

21 September 2018

Caspase inhibitors improve survival in sepsis: a critical role of the lymphocyte

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211770

21 September 2018

Executioner caspase-3, -6, and -7 perform distinct, non-redundant roles during the demolition phase of apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211770

21 September 2018

Apoptosis in lymphoid and parenchymal cells during sepsis: findings in normal and T- and B-cell-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2211770

21 September 2018

Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20031791

21 January 2018

Simultaneous Degradation of αII- and βII-Spectrin by Caspase 3 (CPP32) in Apoptotic Cells

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20031791

21 January 2018

Sepsis-induced apoptosis causes progressive profound depletion of B and CD4+ T lymphocytes in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/14718517

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of Bcl-2 in the intestinal epithelium improves survival in septic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/14718517

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of intestinal epithelial apoptosis and survival in a murine model of pneumonia-induced sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/14718517

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential induction of apoptosis in lymphoid tissues during sepsis: variation in onset, frequency, and the nature of the mediators

1 reference

https://pubmed.ncbi.nlm.nih.gov/14718517

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1084/JEM.20031791

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

ResearchGate publication ID

0 references

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