(Q36402056)

14 August 2017

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title

Congenital heart diseases in small animals: part I. Genetic pathways and potential candidate genes (English)

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14 August 2017

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Changbaig Hyun

1

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14 August 2017

Lopeti Lavulo

series ordinal

2

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14 August 2017

language of work or name

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1 March 2006

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14 August 2017

published in

The Veterinary Journal

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14 August 2017

volume

171

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14 August 2017

issue

2

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14 August 2017

page(s)

245-255

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Canine tricuspid valve malformation, a model of human Ebstein anomaly, maps to dog chromosome 9.

14 August 2017

cites work

1 reference

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BMP-2 induces ectopic expression of cardiac lineage markers and interferes with somite formation in chicken embryos.

7 January 2021

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Mouse GATA-4: a retinoic acid-inducible GATA-binding transcription factor expressed in endodermally derived tissues and heart

7 January 2021

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Early events in valvulogenesis: a signaling perspective

7 January 2021

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Double-outlet right ventricle and overriding tricuspid valve reflect disturbances of looping, myocardialization, endocardial cushion differentiation, and apoptosis in TGF-beta(2)-knockout mice

7 January 2021

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Mutations in human TBX5 [corrected] cause limb and cardiac malformation in Holt-Oram syndrome

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Mutations in the cardiac transcription factor NKX2.5 affect diverse cardiac developmental pathways

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Cardiac septal and valvular dysmorphogenesis in mice heterozygous for mutations in the homeobox gene Nkx2-5

7 January 2021

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A novel mechanism for regulating transforming growth factor beta (TGF-beta) signaling. Functional modulation of type III TGF-beta receptor expression through interaction with the PDZ domain protein, GIPC

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Heart development: molecular insights into cardiac specification and early morphogenesis

7 January 2021

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Expressivity of Holt-Oram syndrome is not predicted by TBX5 genotype

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Cardiac expression of the ventricle-specific homeobox gene Irx4 is modulated by Nkx2-5 and dHand

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Cardiomyopathy in Irx4-deficient mice is preceded by abnormal ventricular gene expression

7 January 2021

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A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease

7 January 2021

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Disruption of hyaluronan synthase-2 abrogates normal cardiac morphogenesis and hyaluronan-mediated transformation of epithelium to mesenchyme

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Heart-valve mesenchyme formation is dependent on hyaluronan-augmented activation of ErbB2-ErbB3 receptors

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Opening of compacted chromatin by early developmental transcription factors HNF3 (FoxA) and GATA-4

7 January 2021

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Hyperplastic conotruncal endocardial cushions and transposition of great arteries in perlecan-null mice.

7 January 2021

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Proper coronary vascular development and heart morphogenesis depend on interaction of GATA-4 with FOG cofactors

7 January 2021

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Expression of the Novel Basic Helix-Loop-Helix Gene eHAND in Neural Crest Derivatives and Extraembryonic Membranes during Mouse Development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

The basic helix-loop-helix factor, HAND2, functions as a transcriptional activator by binding to E-boxes as a heterodimer

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

BMP signaling is required for septation of the outflow tract of the mammalian heart

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Induction of normal cardiovascular development in the vitamin A-deprived quail embryo by natural retinoids

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Tetralogy of fallot and other congenital heart defects in Hey2 mutant mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Molecular regulation of atrioventricular valvuloseptal morphogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Heart and extra-embryonic mesodermal defects in mouse embryos lacking the bHLH transcription factor Hand1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Anterior endoderm is sufficient to rescue foregut apoptosis and heart tube morphogenesis in an embryo lacking retinoic acid.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

NKX2.5 mutations in patients with tetralogy of fallot

7 January 2021

2 references

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

7 January 2021

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

inferred from DOI database lookup

7 January 2021

based on heuristic

NK-2 homeobox genes and heart development

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Patterning the vertebrate heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Recombinant domain IV of perlecan binds to nidogens, laminin-nidogen complex, fibronectin, fibulin-2 and heparin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Molecular mechanisms of transforming growth factor-beta signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Identification of a GATA motif in the cardiac alpha-myosin heavy-chain-encoding gene and isolation of a human GATA-4 cDNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Congenital heart diseases in small animals: part II. Potential genetic aetiologies based on human genetic studies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Smad6 inhibits signalling by the TGF-beta superfamily

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

DiGeorge syndrome phenotype in mice mutant for the T-box gene, Tbx1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

The mouse short ear skeletal morphogenesis locus is associated with defects in a bone morphogenetic member of the TGF beta superfamily

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Molecular embryogenesis of the heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Csx: a murine homeobox-containing gene specifically expressed in the developing heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Retinoid signaling required for normal heart development regulates GATA-4 in a pathway distinct from cardiomyocyte differentiation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

SMADs: mediators and regulators of TGF-beta signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Cardiac septation: a late contribution of the embryonic primary myocardium to heart morphogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Abnormal angiogenesis but intact hematopoietic potential in TGF-beta type I receptor-deficient mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Hey genes: a novel subfamily of hairy- and Enhancer of split related genes specifically expressed during mouse embryogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Formation of multiple hearts in mice following deletion of beta-catenin in the embryonic endoderm

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Inhibition of Wnt activity induces heart formation from posterior mesoderm

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Differences in left-right axis pathways in mouse and chick: functions of FGF8 and SHH

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: involvement of type I receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

The Cspg2 gene, disrupted in the hdf mutant, is required for right cardiac chamber and endocardial cushion formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Transcription factor GATA-4 regulates cardiac muscle-specific expression of the alpha-myosin heavy-chain gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

HRT1, HRT2, and HRT3: a new subclass of bHLH transcription factors marking specific cardiac, somitic, and pharyngeal arch segments

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Members of the HRT family of basic helix-loop-helix proteins act as transcriptional repressors downstream of Notch signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

The proteoglycans aggrecan and Versican form networks with fibulin-2 through their lectin domain binding

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Molecular pathways controlling heart development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Wnt-11 activation of a non-canonical Wnt signalling pathway is required for cardiogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

GATA4 haploinsufficiency in patients with interstitial deletion of chromosome region 8p23.1 and congenital heart disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

The orphan nuclear receptor COUP-TFII is required for angiogenesis and heart development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Differential expression and function of Tbx5 and Tbx20 in cardiac development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

The Hand1 bHLH transcription factor is essential for placentation and cardiac morphogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

BMP2 is required for early heart development during a distinct time period.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Congenital heart disease caused by mutations in the transcription factor NKX2-5

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

A role for bone morphogenetic proteins in the induction of cardiac myogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Assignment of cardiac homeobox gene CSX to human chromosome 5q34

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

A subclass of bHLH proteins required for cardiac morphogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

A genetic blueprint for cardiac development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Characterization of type I receptors for transforming growth factor-beta and activin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Role of TBX1 in human del22q11.2 syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

The basic helix-loop-helix transcription factor, dHAND, is required for vascular development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Expression of chick Tbx-2, Tbx-3, and Tbx-5 genes during early heart development: evidence for BMP2 induction of Tbx2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Extracellular matrix protein fibulin-2 is expressed in the embryonic endocardial cushion tissue and is a prominent component of valves in adult heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R symmetry by the mouse node

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TVJL.2005.02.008

10.1016/J.TVJL.2005.02.008

7 January 2021

Identifiers

DOI

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14 August 2017

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