(Q36403378)

14 August 2017

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title

Function and regulation of Rnd proteins (English)

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14 August 2017

Pierre Chardin

1

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14 August 2017

1 January 2006

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Nature Reviews Molecular Cell Biology

14 August 2017

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14 August 2017

7

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14 August 2017

54-62

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14 August 2017

1

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https://scigraph.springernature.com/pub.10.1038/nrm1788

14 August 2017

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Differential gene expression patterns by oligonucleotide microarray of basal versus lipopolysaccharide-activated monocytes from cord blood versus adult peripheral blood

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Ascidians as a vertebrate-like model organism for physiological studies of Rho GTPase signaling

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A new member of the Rho family, Rnd1, promotes disassembly of actin filament structures and loss of cell adhesion

31 March 2020

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Crystal structure of the core domain of RhoE/Rnd3: a constitutively activated small G protein

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RhoE binds to ROCK I and inhibits downstream signaling

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Rnd proteins function as RhoA antagonists by activating p190 RhoGAP

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Socius is a novel Rnd GTPase-interacting protein involved in disassembly of actin stress fibers.

31 March 2020

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Rho family GTPase Rnd2 interacts and co-localizes with MgcRacGAP in male germ cells

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An ECT2-centralspindlin complex regulates the localization and function of RhoA

31 March 2020

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Semaphorins command cells to move

31 March 2020

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The Semaphorin 4D receptor Plexin-B1 is a GTPase activating protein for R-Ras

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Direct interaction of Rnd1 with Plexin-B1 regulates PDZ-RhoGEF-mediated Rho activation by Plexin-B1 and induces cell contraction in COS-7 cells

31 March 2020

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The semaphorin 3A receptor may directly regulate the activity of small GTPases.

31 March 2020

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Antagonistic effects of Rnd1 and RhoD GTPases regulate receptor activity in Semaphorin 3A-induced cytoskeletal collapse.

31 March 2020

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Plexin signaling hampers integrin-based adhesion, leading to Rho-kinase independent cell rounding, and inhibiting lamellipodia extension and cell motility

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Conversion of neuronal growth cone responses from repulsion to attraction by cyclic nucleotides.

31 March 2020

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Cyclic GMP-dependent protein kinase signaling pathway inhibits RhoA-induced Ca2+ sensitization of contraction in vascular smooth muscle

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Direct interaction of Rnd1 with FRS2 beta regulates Rnd1-induced down-regulation of RhoA activity and is involved in fibroblast growth factor-induced neurite outgrowth in PC12 cells

31 March 2020

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Regulating axon branch stability: the role of p190 RhoGAP in repressing a retraction signaling pathway.

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p190 RhoGAP is the principal Src substrate in brain and regulates axon outgrowth, guidance and fasciculation

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Induced expression of Rnd3 is associated with transformation of polarized epithelial cells by the Raf-MEK-extracellular signal-regulated kinase pathway

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Modulation of RhoA-Rho kinase-mediated Ca2+ sensitization of rabbit myometrium during pregnancy - role of Rnd3

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Up-regulation of Rnd1 during pregnancy serves as a negative-feedback control for Ca2+ sensitization of contractile elements in rat myometrium

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Role of Rho kinase signalling in healthy and varicose human saphenous veins.

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Discovery of aberrant expression of R-RAS by cancer-linked DNA hypomethylation in gastric cancer using microarrays

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RhoE function is regulated by ROCK I-mediated phosphorylation

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CNF1 exploits the ubiquitin-proteasome machinery to restrict Rho GTPase activation for bacterial host cell invasion

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Regulation of cell polarity and protrusion formation by targeting RhoA for degradation

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ARAP3 is a PI3K- and rap-regulated GAP for RhoA

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Phosphorylation of serine 188 protects RhoA from ubiquitin/proteasome-mediated degradation in vascular smooth muscle cells

31 March 2020

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RAS and RHO GTPases in G1-phase cell-cycle regulation

31 March 2020

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Small G-protein RhoE is underexpressed in prostate cancer and induces cell cycle arrest and apoptosis

31 March 2020

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Rnd3/RhoE induces tight junction formation in mammary epithelial tumor cells

31 March 2020

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Growth-suppressive effect of non-steroidal anti-inflammatory drugs on 11 colon-cancer cell lines and fluorescence differential display of genes whose expression is influenced by sulindac

31 March 2020

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Expression analysis of neuroleukin, calmodulin, cortactin, and Rho7/Rnd2 in the intact and injured mouse brain

31 March 2020

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Genomic analysis of metastasis reveals an essential role for RhoC

31 March 2020

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Gene expression profiling and subgroup identification of oligodendrogliomas

31 March 2020

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Prediction of central nervous system embryonal tumour outcome based on gene expression

31 March 2020

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Identification of genes involved in estrogenic action in the human prostate using microarray analysis

31 March 2020

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Simultaneous suppression of progression marker genes in the highly malignant human melanoma cell line BLM after transfection with the adenovirus-5 E1A gene

31 March 2020

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Complete genomic sequence and analysis of 117 kb of human DNA containing the gene BRCA1

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRM1788

1 reference

14 August 2017

1 reference

PubMed ID

16493413