(Q36404284)

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Pancreatic beta cell-specific expression of thioredoxin, an antioxidative and antiapoptotic protein, prevents autoimmune and streptozotocin-induced diabetes

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9782121%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

Pancreatic beta cell-specific expression of thioredoxin, an antioxidative and antiapoptotic protein, prevents autoimmune and streptozotocin-induced diabetes (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9782121%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

Jun-ichi Miyazaki

7

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5 December 2019

author name string

M Hotta

1

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5 December 2019

F Tashiro

2

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5 December 2019

H Ikegami

3

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5 December 2019

H Niwa

4

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5 December 2019

T Ogihara

5

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5 December 2019

J Yodoi

6

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5 December 2019

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1 October 1998

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5 December 2019

Journal of Experimental Medicine

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5 December 2019

188

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5 December 2019

1445-1451

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5 December 2019

8

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Europe PubMed Central

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5 December 2019

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

30 September 2017

A mechanism for all polymerases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

30 September 2017

Mechanisms of the regulation of thioredoxin reductase activity in cancer cells by the chemopreventive agent selenium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

30 September 2017

Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

30 September 2017

Requirement of Fas for the development of autoimmune diabetes in nonobese diabetic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

30 September 2017

Redox regulation of cellular activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

30 September 2017

AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

30 September 2017

AP-1 function and regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

30 September 2017

Beta cell apoptosis in T cell-mediated autoimmune diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

30 September 2017

The role of interleukin-1 in the pathogenesis of IDDM.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

30 September 2017

The harmony of the spheres: inducible nitric oxide synthase and related genes in pancreatic beta cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

30 September 2017

The solution structure of human thioredoxin complexed with its target from Ref-1 reveals peptide chain reversal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

30 September 2017

Checkpoints in the progression of autoimmune disease: lessons from diabetes models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

30 September 2017

Redox control of resistance to cis-diamminedichloroplatinum (II) (CDDP): protective effect of human thioredoxin against CDDP-induced cytotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

30 September 2017

Distinct effects of thioredoxin and antioxidants on the activation of transcription factors NF-kappa B and AP-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

30 September 2017

Solution structure of human thioredoxin in a mixed disulfide intermediate complex with its target peptide from the transcription factor NF kappa B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

30 September 2017

Determinants of the selective toxicity of alloxan to the pancreatic B cell

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

30 September 2017

Breeding of a non-obese, diabetic strain of mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

30 September 2017

Diabetogenic action of streptozotocin: relationship of dose to metabolic response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

30 September 2017

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

30 September 2017

Interleukin 1 beta induces the formation of nitric oxide by beta-cells purified from rodent islets of Langerhans. Evidence for the beta-cell as a source and site of action of nitric oxide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

30 September 2017

The murine autoimmune diabetes model: NOD and related strains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

30 September 2017

Superoxide dismutase, catalase and scavengers of hydroxyl radical protect against the toxic action of alloxan on pancreatic islet cells in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

30 September 2017

Apoptotic cell death triggered by nitric oxide in pancreatic beta-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

30 September 2017

Targeted overexpression of Cu/Zn superoxide dismutase protects pancreatic beta-cells against oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

28 June 2018

Rel/NF-kappa B transcription factors and the control of apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

28 June 2018

CuZn-superoxide dismutase, Mn-superoxide dismutase, catalase and glutathione peroxidase in pancreatic islets and other tissues in the mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

28 June 2018

Interaction of mutant thioredoxins of Escherichia coli with the gene 5 protein of phage T7. The redox capacity of thioredoxin is not required for stimulation of DNA polymerase activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

28 June 2018

Immunohistochemical localization of thioredoxin and thioredoxin reductase in mouse exocrine and endocrine pancreas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

28 June 2018

Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

28 June 2018

Protective activity of adult T cell leukemia-derived factor (ADF) against tumor necrosis factor-dependent cytotoxicity on U937 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

28 June 2018

Reactive oxygen-reducing and protein-refolding activities of adult T cell leukemia-derived factor/human thioredoxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

28 June 2018

Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

21 September 2018

Antioxidant enzyme activities in IDD-prone and IDD-resistant mice: a comparative study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2213419

21 September 2018

Treatment of cultured pancreatic B-cells with streptozotocin induces cell death by apoptosis

1 reference

https://api.crossref.org/works/10.1084%2FJEM.188.8.1445

21 January 2018

The role of Fas in autoimmune diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9782121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathologic anatomy of the pancreas in juvenile diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/9782121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis is the mode of beta-cell death responsible for the development of IDDM in the nonobese diabetic (NOD) mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/9782121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thioredoxin, a gene found overexpressed in human cancer, inhibits apoptosis in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/9782121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transgenic mice overexpressing type 2 nitric-oxide synthase in pancreatic beta cells develop insulin-dependent diabetes without insulitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9782121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Superoxide dismutase in human islets of Langerhans

1 reference

https://pubmed.ncbi.nlm.nih.gov/9782121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rat liver thioredoxin and thioredoxin reductase: purification and characterization

1 reference

https://pubmed.ncbi.nlm.nih.gov/9782121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene transfer into mouse embryos: production of transgenic mice by pronuclear injection

1 reference

https://pubmed.ncbi.nlm.nih.gov/9782121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An improved method for isolation of mouse pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/9782121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular levels of thioredoxin associated with drug sensitivity to cisplatin, mitomycin C, doxorubicin, and etoposide

1 reference

https://pubmed.ncbi.nlm.nih.gov/9782121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inducible nitric oxide synthase (iNOS) in pancreatic islets of nonobese diabetic mice: identification of iNOS- expressing cells and relationships to cytokines expressed in the islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/9782121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thioredoxin and thioredoxin reductase gene expression in human tumors and cell lines, and the effects of serum stimulation and hypoxia

1 reference

https://pubmed.ncbi.nlm.nih.gov/9782121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The immunosuppressant FK-506 prevents progression of diabetes in nonobese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/9782121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activated macrophages kill pancreatic syngeneic islet cells via arginine-dependent nitric oxide generation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9782121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of cytosolic Ca2+ in impaired sensitivity to glucose of rat pancreatic islets exposed to high glucose in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/9782121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEOTIDES. IV. ISOLATION AND CHARACTERIZATION OF THIOREDOXIN, THE HYDROGEN DONOR FROM ESCHERICHIA COLI B

1 reference

https://pubmed.ncbi.nlm.nih.gov/9782121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1084/JEM.188.8.1445

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9782121%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9782121%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9782121%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

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