(Q36412245)

English

Asymmetric and independent contribution of the second transmembrane segment 12' residues to diliganded gating of acetylcholine receptor channels: a single-channel study with choline as the agonist

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scholarly article

1 reference

Europe PubMed Central

14 August 2017

Asymmetric and independent contribution of the second transmembrane segment 12' residues to diliganded gating of acetylcholine receptor channels: a single-channel study with choline as the agonist (English)

1 reference

Europe PubMed Central

14 August 2017

transmembrane protein

0 references

author name string

C Grosman

1

1 reference

Europe PubMed Central

14 August 2017

A Auerbach

2

1 reference

Europe PubMed Central

14 August 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

1 May 2000

1 reference

Europe PubMed Central

14 August 2017

The Journal of General Physiology

1 reference

Europe PubMed Central

14 August 2017

115

1 reference

Europe PubMed Central

14 August 2017

637-651

1 reference

Europe PubMed Central

14 August 2017

5

1 reference

Europe PubMed Central

14 August 2017

Kinetic, mechanistic, and structural aspects of unliganded gating of acetylcholine receptor channels: a single-channel study of second transmembrane segment 12' mutants

1 reference

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30 September 2017

Mapping the conformational wave of acetylcholine receptor channel gating

1 reference

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30 September 2017

Serum choline activates mutant acetylcholine receptors that cause slow channel congenital myasthenic syndromes

1 reference

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30 September 2017

Desensitization of mouse nicotinic acetylcholine receptor channels. A two-gate mechanism

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30 September 2017

A distinct contribution of the delta subunit to acetylcholine receptor channel activation revealed by mutations of the M2 segment

1 reference

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A transmembrane helix dimer: structure and implications

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Detection of changes in pairwise interactions during allosteric transitions: coupling between local and global conformational changes in GroEL

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Potential use of additivity of mutational effects in simplifying protein engineering

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The emerging three-dimensional structure of a receptor. The nicotinic acetylcholine receptor

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Estimating single-channel kinetic parameters from idealized patch-clamp data containing missed events

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Characterizing transition states in protein folding: an essential step in the puzzle

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30 September 2017

Photolabeling reveals the proximity of the alpha-neurotoxin binding site to the M2 helix of the ion channel in the nicotinic acetylcholine receptor.

1 reference

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30 September 2017

Congenital myasthenic syndrome caused by prolonged acetylcholine receptor channel openings due to a mutation in the M2 domain of the epsilon subunit

1 reference

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30 September 2017

Agonists block currents through acetylcholine receptor channels

1 reference

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30 September 2017

Estimating kinetic constants from single channel data

1 reference

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30 September 2017

Protein volume in solution

1 reference

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30 September 2017

Trapping of an open-channel blocker at the frog neuromuscular acetylcholine channel

1 reference

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30 September 2017

Tris+/Na+ permeability ratios of nicotinic acetylcholine receptors are reduced by mutations near the intracellular end of the M2 region

1 reference

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30 September 2017

Local anaesthetics transiently block currents through single acetylcholine-receptor channels

1 reference

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30 September 2017

A quantitative analysis of local anaesthetic alteration of miniature end-plate currents and end-plate current fluctuations

1 reference

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30 September 2017

Additivity principles in biochemistry

1 reference

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30 September 2017

Alteration in ion channel function of mouse nicotinic acetylcholine receptor by mutations in the M4 transmembrane domain

1 reference

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28 June 2018

Uncoupling hydrophobicity and helicity in transmembrane segments. Alpha-helical propensities of the amino acids in non-polar environments.

1 reference

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Mutations at lipid-exposed residues of the acetylcholine receptor affect its gating kinetics

1 reference

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28 June 2018

The location of the gate in the acetylcholine receptor channel.

1 reference

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28 June 2018

Contribution of the beta subunit M2 segment to the ion-conducting pathway of the acetylcholine receptor

1 reference

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28 June 2018

Mutation in the M1 domain of the acetylcholine receptor alpha subunit decreases the rate of agonist dissociation

1 reference

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Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors

1 reference

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On the stochastic properties of single ion channels

2 references

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28 June 2018

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21 January 2018

Synergism in folding of a double mutant of the alpha subunit of tryptophan synthase

1 reference

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Long-range electrostatic interactions can influence the folding, stability, and cooperativity of dihydrofolate reductase.

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Activation of ion channels in the frog end-plate by high concentrations of acetylcholine

1 reference

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Additivity of mutational effects in proteins

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Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic.

1 reference

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28 June 2018

Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the alpha subunit.

1 reference

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21 January 2018

Role of the putative transmembrane segment M3 in gating of neuronal nicotinic receptors.

1 reference

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21 January 2018

Backbone mutations in transmembrane domains of a ligand-gated ion channel: implications for the mechanism of gating.

1 reference

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21 January 2018

A Correlation of Reaction Rates

1 reference

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21 January 2018

The charge carried by single-channel currents of rat cultured muscle cells in the presence of local anaesthetics.

1 reference

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21 January 2018

Maximum likelihood estimation of aggregated Markov processes.

1 reference

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21 January 2018

Parameters for the Description of Transition States

1 reference

https://api.crossref.org/works/10.1085%2FJGP.115.5.637

21 January 2018

Acetylcholine receptor M3 domain: stereochemical and volume contributions to channel gating

1 reference

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21 January 2018

The role of conserved leucines in the M2 domain of the acetylcholine receptor in channel gating.

1 reference

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21 September 2018

Quantitative analysis of structure–activity relationships in engineered proteins by linear free-energy relationships

1 reference

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21 January 2018

Single acetylcholine-activated channels show burst-kinetics in presence of desensitizing concentrations of agonist

1 reference

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21 January 2018

Acetylcholine receptor channel imaged in the open state

1 reference

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21 January 2018

The use of double mutants to detect structural changes in the active site of the tyrosyl-tRNA synthetase (Bacillus stearothermophilus)

1 reference

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21 January 2018

Mutational analysis of the charge selectivity filter of the alpha7 nicotinic acetylcholine receptor

1 reference

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21 January 2018

Artifacts in the application of linear free energy analysis

1 reference

https://api.crossref.org/works/10.1085%2FJGP.115.5.637

21 January 2018

Linear free energy relationships are valid!

1 reference

https://api.crossref.org/works/10.1085%2FJGP.115.5.637

21 January 2018

The channel opening rate of adult- and fetal-type mouse muscle nicotinic receptors activated by acetylcholine

1 reference

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21 January 2018

Location of a threonine residue in the α -subunit M2 transmembrane segment that determines the ion flow through the acetylcholine receptor channel

1 reference

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21 January 2018

Identifiers

10.1085/JGP.115.5.637

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

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