(Q36412573)

English

Methylation of cytosine at C5 in a CpG sequence context causes a conformational switch of a benzo[a]pyrene diol epoxide-N2-guanine adduct in DNA from a minor groove alignment to intercalation with base displacement

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1 reference

Europe PubMed Central

14 August 2017

Methylation of cytosine at C5 in a CpG sequence context causes a conformational switch of a benzo[a]pyrene diol epoxide-N2-guanine adduct in DNA from a minor groove alignment to intercalation with base displacement (English)

1 reference

Europe PubMed Central

14 August 2017

sequence alignment

1 reference

based on heuristic

inferred from title

7

object named as

Suse Broyde

1 reference

Europe PubMed Central

14 August 2017

author name string

Na Zhang

1

1 reference

Europe PubMed Central

14 August 2017

Chin Lin

2

1 reference

Europe PubMed Central

14 August 2017

Xuanwei Huang

3

1 reference

Europe PubMed Central

14 August 2017

Aleksandr Kolbanovskiy

4

1 reference

Europe PubMed Central

14 August 2017

Brian E Hingerty

5

1 reference

Europe PubMed Central

14 August 2017

Shantu Amin

6

1 reference

Europe PubMed Central

14 August 2017

Nicholas E Geacintov

8

1 reference

Europe PubMed Central

14 August 2017

Dinshaw J Patel

9

1 reference

Europe PubMed Central

14 August 2017

language of work or name

0 references

publication date

31 December 2004

1 reference

Europe PubMed Central

14 August 2017

Journal of Molecular Biology

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Europe PubMed Central

14 August 2017

346

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Europe PubMed Central

14 August 2017

951-965

1 reference

Europe PubMed Central

14 August 2017

4

1 reference

Europe PubMed Central

14 August 2017

On the origin of G --> T transversions in lung cancer

1 reference

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30 September 2017

Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancers

1 reference

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30 September 2017

Accurate representation of B-DNA double helical structure with implicit solvent and counterions

1 reference

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30 September 2017

Dynamic impact of methylation at the M. Hhai target site: a solid-state deuterium NMR study

1 reference

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30 September 2017

Impact of CpG methylation on structure, dynamics and solvation of cAMP DNA responsive element

1 reference

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30 September 2017

Molecular topology of polycyclic aromatic carcinogens determines DNA adduct conformation: a link to tumorigenic activity

1 reference

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30 September 2017

p53 mutational spectra and the role of methylated CpG sequences

1 reference

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30 September 2017

Mutation hotspots and DNA methylation.

1 reference

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30 September 2017

p53 mutation spectrum and load: the generation of hypotheses linking the exposure of endogenous or exogenous carcinogens to human cancer

1 reference

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30 September 2017

Implications of cytosine methylation on (+)-anti-Benzo[a]pyrene 7, 8-dihydrodiol 9,10-epoxide N(2)-dG adduct formation in 5'-d(CGT), 5'-d(CGA), and 5'-d(CGC) sequence contexts of single- and double-stranded oligonucleotides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

30 September 2017

Molecular epidemiology of human cancer risk: gene-environment interactions and p53 mutation spectrum in human lung cancer

1 reference

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30 September 2017

Mutagenic potential of stereoisomeric bay region (+)- and (-)-cis-anti-benzo[a]pyrene diol epoxide-N2-2'-deoxyguanosine adducts in Escherichia coli and simian kidney cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

30 September 2017

Role of hydrophobic effects in the reaction of a polynuclear aromatic diol epoxide with oligodeoxynucleotides in aqueous solutions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

30 September 2017

Base pair conformation-dependent excision of benzo[a]pyrene diol epoxide-guanine adducts by human nucleotide excision repair enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

30 September 2017

Cytosine methylation determines hot spots of DNA damage in the human P53 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

30 September 2017

Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

30 September 2017

Somatic point mutations in the p53 gene of human tumors and cell lines: updated compilation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

30 September 2017

Interaction of the UvrABC nuclease system with a DNA duplex containing a single stereoisomer of dG-(+)- or dG-(-)-anti-BPDE.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

30 September 2017

Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons: G. H. A. Clowes Memorial Lecture.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

30 September 2017

Nucleic acids and nuclear magnetic resonance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

30 September 2017

DNA and RNA: NMR studies of conformations and dynamics in solution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

30 September 2017

Covalent bonding of bay-region diol epoxides to nucleic acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

30 September 2017

Spectroscopic characteristics and site I/site II classification of cis and trans benzo[a]pyrene diolepoxide enantiomer-guanosine adducts in oligonucleotides and polynucleotides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

30 September 2017

Biological aspects of cytosine methylation in eukaryotic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

30 September 2017

Solution conformation of the major adduct between the carcinogen (+)-anti-benzo[a]pyrene diol epoxide and DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

30 September 2017

Differences in mutagenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

30 September 2017

Tumorigenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides in newborn mice: exceptional activity of (+)-7beta,8alpha-dihydroxy-9alpha,10alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

30 September 2017

NMR solution structures of stereoisometric covalent polycyclic aromatic carcinogen-DNA adduct: principles, patterns, and diversity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

30 September 2017

Solution conformation of the (+)-cis-anti-[BP]dG adduct in a DNA duplex: intercalation of the covalently attached benzo[a]pyrenyl ring into the helix and displacement of the modified deoxyguanosine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

28 June 2018

Cellular differentiation, cytidine analogs and DNA methylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

28 June 2018

Noncovalent intercalative complex formation and kinetic flow linear dichroism of racemic syn- and anti-benzo[a]pyrenediol epoxide-DNA solutions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

28 June 2018

Formation of diastereomeric benzo[a]pyrene diol epoxide-guanine adducts in p53 gene-derived DNA sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

21 September 2018

Benzo[a]pyrene diol epoxide forms covalent adducts with deoxycytidylic acid by alkylation at both exocyclic amino N(4) and ring imino N-3 positions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

21 September 2018

C5-methylation of cytosine in B-DNA thermodynamically and kinetically stabilizes BI.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

21 September 2018

Preferential carcinogen-DNA adduct formation at codons 12 and 14 in the human K-ras gene and their possible mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

21 September 2018

Modulation of human nucleotide excision repair by 5-methylcytosines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

21 September 2018

Structural effects of cytosine methylation on DNA sugar pucker studied by FTIR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

21 September 2018

On the origin of p53 G:C --> T:A transversions in lung cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

21 September 2018

Formation of benzo[a]pyrene diol epoxide-DNA adducts at specific guanines within K-ras and p53 gene sequences: stable isotope-labeling mass spectrometry approach

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

21 September 2018

Conformational changes of a benzo[a]pyrene diol epoxide-N(2)-dG adduct induced by a 5'-flanking 5-methyl-substituted cytosine in a (Me)CG double-stranded oligonucleotide sequence context

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

21 September 2018

Methylated CpG dinucleotides are the preferential targets for G-to-T transversion mutations induced by benzo[a]pyrene diol epoxide in mammalian cells: similarities with the p53 mutation spectrum in smoking-associated lung cancers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

21 September 2018

Sequence context profoundly influences the mutagenic potency of trans-opened benzo[a]pyrene 7,8-diol 9,10-epoxide-purine nucleoside adducts in site-specific mutation studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

21 September 2018

Carcinogens preferentially bind at methylated CpG in the p53 mutational hot spots.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

21 September 2018

The major, N2-dG adduct of (+)-anti-B[a]PDE shows a dramatically different mutagenic specificity (predominantly, G --> A) in a 5'-CGT-3' sequence context.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

21 September 2018

Sequence specific mutagenesis of the major (+)-anti-benzo[a]pyrene diol epoxide-DNA adduct at a mutational hot spot in vitro and in Escherichia coli cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

21 September 2018

Mutagenic selectivity at the HPRT locus in V-79 cells: comparison of mutations caused by bay-region benzo[a]pyrene 7,8-diol-9,-10-epoxide enantiomers with high and low carcinogenic activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

21 September 2018

DNA adducts from carcinogenic and noncarcinogenic enantiomers of benzo[a]pyrene dihydrodiol epoxide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4694590

21 October 2018

Binding of Nenzo[ a ]pyrene 7,8-Diol-9,10-Epoxides to DNA, RNA, and Protein of Mouse Skin Occurs with High Stereoselectivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15701509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Benzo(a)pyrene diol epoxides as intermediates in nucleic acid binding in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/15701509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of DNA structure from sequence: a build-up technique

1 reference

https://pubmed.ncbi.nlm.nih.gov/15701509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Solution conformation of the (+)-cis-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the minor groove

1 reference

https://pubmed.ncbi.nlm.nih.gov/15701509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Base-sequence dependence of noncovalent complex formation and reactivity of benzo[a]pyrene diol epoxide with polynucleotides

1 reference

https://pubmed.ncbi.nlm.nih.gov/15701509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

C-C-A-G-G-C-m5C-T-G-G. Helical fine structure, hydration, and comparison with C-C-A-G-G-C-C-T-G-G

1 reference

https://pubmed.ncbi.nlm.nih.gov/15701509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Base stacking and molecular polarizability: effect of a methyl group in the 5-position of pyrimidines

1 reference

https://pubmed.ncbi.nlm.nih.gov/15701509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Marked differences in the skin tumor-initiating activities of the optical enantiomers of the diastereomeric benzo(a)pyrene 7,8-diol-9,10-epoxides

1 reference

https://pubmed.ncbi.nlm.nih.gov/15701509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Investigation of the influence of cytosine methylation on DNA flexibility

1 reference

https://pubmed.ncbi.nlm.nih.gov/15701509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of benzo[a]pyrene diol epoxide chirality on solution conformations of DNA covalent adducts: the (-)-trans-anti-[BP]G.C adduct structure and comparison with the (+)-trans-anti-[BP]G.C enantiomer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15701509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fidelity of translesional synthesis past benzo[a]pyrene diol epoxide-2'-deoxyguanosine DNA adducts: marked effects of host cell, sequence context, and chirality

1 reference

https://pubmed.ncbi.nlm.nih.gov/15701509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unrepaired fjord region polycyclic aromatic hydrocarbon-DNA adducts in ras codon 61 mutational hot spots

1 reference

https://pubmed.ncbi.nlm.nih.gov/15701509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytosine methylation in a CpG sequence leads to enhanced reactivity with Benzo[a]pyrene diol epoxide that correlates with a conformational change

1 reference

https://pubmed.ncbi.nlm.nih.gov/15701509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytosine methylation can induce local distortions in the structure of duplex DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/15701509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Solution conformation of the (-)-cis-anti-benzo[a]pyrenyl-dG adduct opposite dC in a DNA duplex: intercalation of the covalently attached BP ring into the helix with base displacement of the modified deoxyguanosine into the major groove

1 reference

https://pubmed.ncbi.nlm.nih.gov/15701509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

How stereochemistry affects mutagenesis by N2-deoxyguanosine adducts of 7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene: configuration of the adduct bond is more important than those of the hydroxyl groups

1 reference

https://pubmed.ncbi.nlm.nih.gov/15701509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of C5-cytosine methylation on the solution structure of d(GAAAACGTTTTC)2. An NMR and molecular modelling investigation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15701509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bending and flexibility of methylated and unmethylated EcoRI DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/15701509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53 tumor suppressor gene: from the basic research laboratory to the clinic--an abridged historical perspective

1 reference

https://pubmed.ncbi.nlm.nih.gov/15701509

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.JMB.2004.12.027

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

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