(Q34154480)

31 July 2017

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title

Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancers (English)

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31 July 2017

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6

Pierre Hainaut

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31 July 2017

Gerd P Pfeifer

1

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31 July 2017

Mikhail F Denissenko

2

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31 July 2017

Magali Olivier

3

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31 July 2017

Natalia Tretyakova

4

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31 July 2017

Stephen S Hecht

5

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31 July 2017

language of work or name

English

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publication date

1 October 2002

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31 July 2017

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31 July 2017

volume

21

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31 July 2017

issue

48

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31 July 2017

page(s)

7435-7451

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Interactions of beta-carotene and cigarette smoke in human bronchial epithelial cells

31 July 2017

cites work

1 reference

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7 January 2021

Molecular epidemiology of human cancer risk: gene-environment interactions and p53 mutation spectrum in human lung cancer

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7 January 2021

Biomonitoring of tobacco smoke carcinogenicity by dosimetry of DNA adducts and genotyping and phenotyping of biotransformational enzymes: a review on polycyclic aromatic hydrocarbons

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7 January 2021

Mutagenic specificities of four stereoisomeric benzo[c]phenanthrene dihydrodiol epoxides

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7 January 2021

Association between cigarette smoking and mutation of the p53 gene in squamous-cell carcinoma of the head and neck

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7 January 2021

The chemistry of DNA damage from nitric oxide and peroxynitrite

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7 January 2021

Mutagenic potential of guanine N2 adducts of butadiene mono- and diolepoxide

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7 January 2021

Detection and quantification of depurinated benzo[a]pyrene-adducted DNA bases in the urine of cigarette smokers and women exposed to household coal smoke

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7 January 2021

Gender- and smoking-related bladder cancer risk

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7 January 2021

Cigarette smoking and colorectal cancer mortality in the cancer prevention study II.

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7 January 2021

Effect of excision repair by diploid human fibroblasts on the kinds and locations of mutations induced by (+/-)-7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10- tetrahydrobenzo[a]pyrene in the coding region of the HPRT gene

1 reference

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7 January 2021

A comparison of the mainstream smoke chemistry and mutagenicity of a representative sample of the US cigarette market with two Kentucky reference cigarettes (K1R4F and K1R5F).

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7 January 2021

A comparison of the tumors induced by coal tar and benzo[a]pyrene in a 2-year bioassay.

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7 January 2021

Immunochemical, 32P-postlabeling, and GC/MS detection of 4-aminobiphenyl-DNA adducts in human peripheral lung in relation to metabolic activation pathways involving pulmonary N-oxidation, conjugation, and peroxidation.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Reactivity of guanine at m5CpG steps in DNA: evidence for electronic effects transmitted through the base pairs

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Cytosine methylation determines hot spots of DNA damage in the human P53 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Slow repair of bulky DNA adducts along the nontranscribed strand of the human p53 gene may explain the strand bias of transversion mutations in cancers.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53.

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7 January 2021

Cancers weakly related to smoking

1 reference

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7 January 2021

Carcinogenic epoxides of benzo[a]pyrene and cyclopenta[cd]pyrene induce base substitutions via specific transversions

1 reference

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7 January 2021

N-hydroxy-4-aminobiphenyl-DNA binding in human p53 gene: sequence preference and the effect of C5 cytosine methylation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Mass spectrometric analysis of tobacco-specific nitrosamine-DNA adducts in smokers and nonsmokers

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Is intercalation a critical factor in the covalent binding of mutagenic and tumorigenic polycyclic aromatic diol epoxides to DNA?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Enzymatic oxidation of ethyl carbamate to vinyl carbamate and its role as an intermediate in the formation of 1,N6-ethenoadenosine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Enhancement of pre-existing DNA adducts in rodents exposed to cigarette smoke

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

TP53 mutation spectrum in lung cancers and mutagenic signature of components of tobacco smoke: lessons from the IARC TP53 mutation database

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Patterns of p53 G-->T transversions in lung cancers reflect the primary mutagenic signature of DNA-damage by tobacco smoke

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Tobacco-specific nitrosamines, an important group of carcinogens in tobacco and tobacco smoke.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Biochemistry, biology, and carcinogenicity of tobacco-specific N-nitrosamines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Tobacco smoke carcinogens and lung cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Oxidation of 7,8-dihydro-8-oxoguanine affords lesions that are potent sources of replication errors in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

A specific spectrum of p53 mutations in lung cancer from smokers: review of mutations compiled in the IARC p53 database

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Genome maintenance mechanisms for preventing cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

The less harmful cigarette: a controversial issue. a tribute to Ernst L. Wynder

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

p53 mutations in human cancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Cigarette smoking and p53 mutations in lung cancer and bladder cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Poleta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Molecular dosimetry of N-7 guanine adduct formation in mice and rats exposed to 1,3-butadiene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Butadiene diolepoxide- and diepoxybutane-derived DNA adducts at N7-guanine: a high occurrence of diolepoxide-derived adducts in mouse lung after 1,3-butadiene exposure

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Toward an understanding of the role of DNA adduct conformation in defining mutagenic mechanism based on studies of the major adduct (formed at N(2)-dG) of the potent environmental carcinogen, benzo[a]pyrene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Polycyclic aromatic hydrocarbon-DNA adducts in humans: relevance as biomarkers for exposure and cancer risk

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Mutational specificity of depurination

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Analysis of 4-aminobiphenyl-DNA adducts in human urinary bladder and lung by alkaline hydrolysis and negative ion gas chromatography-mass spectrometry

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

DNA damage control by novel DNA polymerases: translesion replication and mutagenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

In vivo mutagenesis by O6-methylguanine built into a unique site in a viral genome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Sequence specificity of mutations induced by benzo[a]pyrene-7,8-diol-9,10-epoxide at endogenous aprt gene in CHO cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Mutations induced by aromatic amine DNA adducts in pBR322.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Modulation of benzo[a]pyrene-DNA adducts in hamster cheek pouch by chronic ethanol consumption

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Research in chemical carcinogenesis with Elizabeth Miller--a trail of discovery with our associates

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Effect of cadmium exposure on background and anti-5 methylchrysene-1,2-dihydrodiol 3,4-epoxide-induced mutagenesis in the supF gene of pS189 in human Ad293 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Etheno DNA-base adducts from endogenous reactive species

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Mechanistic linkage between DNA adducts, mutations in oncogenes and tumorigenesis of carcinogenic environmental polycyclic aromatic hydrocarbons in strain A/J mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Mutational spectrum induced by acetaldehyde in the HPRT gene of human T lymphocytes resembles that in the p53 gene of esophageal cancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Analysis of the most representative tumour-derived p53 mutants reveals that changes in protein conformation are not correlated with loss of transactivation or inhibition of cell proliferation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Analysis of different versions of the IARC p53 database with respect to G-->T transversion mutation frequencies and mutation hotspots in lung cancer of smokers and non-smokers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Mutagenesis by O(6)-[4-oxo-4-(3-pyridyl)butyl]guanine in Escherichia coli and human cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Dihydrodiol dehydrogenases and polycyclic aromatic hydrocarbon activation: generation of reactive and redox active o-quinones.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

p53 mutational spectra and the role of methylated CpG sequences

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Formation and repair of DNA lesions in the p53 gene: relation to cancer mutations?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Fifty years of benzo(a)pyrene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Tobacco and the global lung cancer epidemic

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Cigarette smoke radicals and the role of free radicals in chemical carcinogenicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Human lung cancer and p53: the interplay between mutagenesis and selection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

G to A transitions and G to T transversions in codon 12 of the Ki-ras oncogene isolated from mouse lung tumors induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and related DNA methylating and pyridyloxobutylating agents.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Polycyclic aromatic hydrocarbons: correlations between DNA adducts and ras oncogene mutations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Synergistic mechanisms in carcinogenesis by polycyclic aromatic hydrocarbons and by tobacco smoke: a bio-historical perspective with updates

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Benzo[a]pyrene-induced murine skin tumors exhibit frequent and characteristic G to T mutations in the p53 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Factors that influence the mutagenic patterns of DNA adducts from chemical carcinogens

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Targeting of lung cancer mutational hotspots by polycyclic aromatic hydrocarbons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

N2-amination of guanine to 2-hydrazinohypoxanthine, a novel in vivo nucleic acid modification produced by the hepatocarcinogen 2-nitropropane

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

DNA adduct formation by polycyclic aromatic hydrocarbon dihydrodiol epoxides

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Disposition of butadiene monoepoxide and butadiene diepoxide in various tissues of rats and mice following a low-level inhalation exposure to 1,3-butadiene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Identification and quantitation of DNA adducts from calf thymus DNA exposed to 3,4-epoxy-1-butene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Evolutionary conservation and somatic mutation hotspot maps of p53: correlation with p53 protein structural and functional features.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Identification of DNA adducts of acetaldehyde.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Identification of paraldol-deoxyguanosine adducts in DNA reacted with crotonaldehyde

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

A Schiff base is a major DNA adduct of crotonaldehyde.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Reactions of alpha-acetoxy-N-nitrosopyrrolidine with deoxyguanosine and DNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Cytosine methylation in a CpG sequence leads to enhanced reactivity with Benzo[a]pyrene diol epoxide that correlates with a conformational change

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Alkyl and aryl carcinogen adducts detected in human peripheral lung

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Successful and not so successful chemoprevention of tobacco smoke-induced lung tumors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Error-prone lesion bypass by human DNA polymerase eta.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Endogenous and background DNA adducts by methylating and 2-hydroxyethylating agents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Human DNA adducts of 1,3-butadiene, an important environmental carcinogen

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205803

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205803

1 reference

Dimensions Publication ID

31 July 2017

1004200719

0 references

1 reference