Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q36414762)
Watch
English
DNA damage and eIF4G1 in breast cancer cells reprogram translation for survival and DNA repair mRNAs
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
3503184
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
title
DNA damage and eIF4G1 in breast cancer cells reprogram translation for survival and DNA repair mRNAs
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3503184
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
main subject
DNA damage
0 references
breast cancer
1 reference
based on heuristic
inferred from title
author
Jiří Zavadil
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
3503184
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
Robert J Schneider
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
3503184
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
author name string
Michelle Badura
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3503184
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
Steve Braunstein
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3503184
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
language of work or name
English
0 references
publication date
29 October 2012
1 reference
stated in
Europe PubMed Central
PMC publication ID
3503184
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
published in
Proceedings of the National Academy of Sciences of the United States of America
1 reference
stated in
Europe PubMed Central
PMC publication ID
3503184
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
volume
109
1 reference
stated in
Europe PubMed Central
PMC publication ID
3503184
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
issue
46
1 reference
stated in
Europe PubMed Central
PMC publication ID
3503184
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
page(s)
18767-18772
1 reference
stated in
Europe PubMed Central
PMC publication ID
3503184
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
cites work
MNK2 inhibits eIF4G activation through a pathway involving serine-arginine-rich protein kinase in skeletal muscle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
Depletion of eIF4G from yeast cells narrows the range of translational efficiencies genome-wide
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
Cap- and IRES-independent scanning mechanism of translation initiation as an alternative to the concept of cellular IRESs.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
Translational control in cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
Functional overlap between eIF4G isoforms in Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
Regulation of protein synthesis by ionizing radiation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
Essential role for eIF4GI overexpression in the pathogenesis of inflammatory breast cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
Direct functional interaction of initiation factor eIF4G with type 1 internal ribosomal entry sites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
Translational reprogramming following UVB irradiation is mediated by DNA-PKcs and allows selective recruitment to the polysomes of mRNAs encoding DNA repair enzymes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
The paradox of autophagy and its implication in cancer etiology and therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
DAP5 promotes cap-independent translation of Bcl-2 and CDK1 to facilitate cell survival during mitosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
eIF4GI links nutrient sensing by mTOR to cell proliferation and inhibition of autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
DNA-damage repair; the good, the bad, and the ugly
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
Eukaryotic nucleotide excision repair: from understanding mechanisms to influencing biology
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
A hypoxia-controlled cap-dependent to cap-independent translation switch in breast cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
DNA damage, cellular senescence and organismal ageing: causal or correlative?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
Caspase-independent autophagic cytotoxicity in etoposide-treated CaSki cervical carcinoma cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
Incorporation of an internal ribosome entry site-dependent mechanism in arsenic-induced GADD45alpha expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
Translational control of meiotic cell cycle progression and spermatid differentiation in male germ cells by a novel eIF4G homolog.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
Frequent overexpression of the genes FXR1, CLAPM1 and EIF4G located on amplicon 3q26-27 in squamous cell carcinoma of the lung
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
Inhibition of mammalian target of rapamycin or apoptotic pathway induces autophagy and radiosensitizes PTEN null prostate cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
GammaH2AX and its role in DNA double-strand break repair
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
HIF-1 and tumour radiosensitivity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
Hypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
Control of mammalian translation by mRNA structure near caps
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
Eukaryotic translation initiation factor 4E availability controls the switch between cap-dependent and internal ribosomal entry site-mediated translation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
Eukaryotic translation initiation factor 4GI and p97 promote cellular internal ribosome entry sequence-driven translation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
Gadd45a, a p53- and BRCA1-regulated stress protein, in cellular response to DNA damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
ATM signaling and genomic stability in response to DNA damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
Upstream and downstream of mTOR
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
53BP1, a mediator of the DNA damage checkpoint
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
Genomic instability, centrosome amplification, cell cycle checkpoints and Gadd45a
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
Structural and functional features of eukaryotic mRNA untranslated regions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
Truncated initiation factor eIF4G lacking an eIF4E binding site can support capped mRNA translation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
Autophagy as a regulated pathway of cellular degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
Internal ribosome initiation of translation and the control of cell death.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
A new internal-ribosome-entry-site motif potentiates XIAP-mediated cytoprotection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
A new translational regulator with homology to eukaryotic translation initiation factor 4G
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
30 September 2017
Therapeutic suppression of translation initiation factor eIF4E expression reduces tumor growth without toxicity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
28 June 2018
Translation eukaryotic initiation factor 4G recognizes a specific structural element within the internal ribosome entry site of encephalomyocarditis virus RNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
28 June 2018
Cap-independent translation is required for starvation-induced differentiation in yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
21 September 2018
A novel eIF4G homolog, Off-schedule, couples translational control to meiosis and differentiation in Drosophila spermatocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
21 September 2018
Targeting the Akt/mammalian target of rapamycin pathway for radiosensitization of breast cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
21 September 2018
Translational upregulation of X-linked inhibitor of apoptosis (XIAP) increases resistance to radiation induced cell death.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
21 September 2018
Translation driven by an eIF4G core domain in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184
retrieved
21 September 2018
Identifiers
DOI
10.1073/PNAS.1203853109
1 reference
stated in
Europe PubMed Central
PMC publication ID
3503184
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
ADS bibcode
2012PNAS..10918767B
0 references
PMC publication ID
3503184
1 reference
stated in
Europe PubMed Central
PMC publication ID
3503184
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
PubMed publication ID
23112151
1 reference
stated in
Europe PubMed Central
PMC publication ID
3503184
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 February 2020
ResearchGate publication ID
232741904
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit