(Q36423203)

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Genetic alterations in fatty acid transport and metabolism genes are associated with metastatic progression and poor prognosis of human cancers.

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26725848%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Genetic alterations in fatty acid transport and metabolism genes are associated with metastatic progression and poor prognosis of human cancers (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26725848%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

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3 March 2020

author name string

Christina Chan

2

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Europe PubMed Central

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3 March 2020

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4 January 2016

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Europe PubMed Central

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3 March 2020

Scientific Reports

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Europe PubMed Central

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3 March 2020

6

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Europe PubMed Central

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3 March 2020

18669

1 reference

Europe PubMed Central

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3 March 2020

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Creative Commons Attribution 4.0 International

4 January 2016

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April 2022 Public Data File from Crossref

copyright status

0 references

https://scigraph.springernature.com/pub.10.1038/srep18669

0 references

Elevated free fatty acid uptake via CD36 promotes epithelial-mesenchymal transition in hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

Cancer stem cell-specific scavenger receptor CD36 drives glioblastoma progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

Epithelial-to-mesenchymal transition rewires the molecular path to PI3K-dependent proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

Cytochrome P450 2E1 (CYP2E1) regulates the response to oxidative stress and migration of breast cancer cells.

1 reference

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30 September 2017

Mutational landscape and significance across 12 major cancer types

1 reference

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30 September 2017

Cellular fatty acid metabolism and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

Loss of caveolin-1 in prostate cancer stroma correlates with reduced relapse-free survival and is functionally relevant to tumour progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

Dysregulated mTORC1 renders cells critically dependent on desaturated lipids for survival under tumor-like stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

Targeting cellular metabolism to improve cancer therapeutics

1 reference

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30 September 2017

Cancer metabolism: fatty acid oxidation in the limelight

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

Mitochondrial complex I activity and NAD+/NADH balance regulate breast cancer progression.

1 reference

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30 September 2017

Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis

1 reference

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30 September 2017

The UCSC Cancer Genomics Browser: update 2013.

1 reference

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30 September 2017

Caveolin 1 expression correlates with poor prognosis and focal adhesion kinase expression in gastric cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

CD36 repression activates a multicellular stromal program shared by high mammographic density and tumor tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data

1 reference

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30 September 2017

Links between metabolism and cancer

1 reference

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30 September 2017

HIF1α induced switch from bivalent to exclusively glycolytic metabolism during ESC-to-EpiSC/hESC transition

1 reference

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30 September 2017

A novel FoxM1-caveolin signaling pathway promotes pancreatic cancer invasion and metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

Caveolin-1 and cancer metabolism in the tumor microenvironment: markers, models, and mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

Roles of PPARs in NAFLD: potential therapeutic targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

Targeting cancer metabolism: a therapeutic window opens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

Increased expression of cytochrome P450 2E1 in nonalcoholic fatty liver disease: mechanisms and pathophysiological role

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

Hallmarks of Cancer: The Next Generation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

Lipoprotein lipase links dietary fat to solid tumor cell proliferation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

Regulation of cancer cell metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

Targeting metabolic transformation for cancer therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

The landscape of somatic copy-number alteration across human cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

CYP2E1 and risk of chemically mediated cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

Understanding the Warburg effect: the metabolic requirements of cell proliferation

1 reference

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30 September 2017

Human SCO2 is required for the synthesis of CO II and as a thiol-disulphide oxidoreductase for SCO1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

Recent insights into hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD).

1 reference

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30 September 2017

Structures of human cytochrome P-450 2E1. Insights into the binding of inhibitors and both small molecular weight and fatty acid substrates

1 reference

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30 September 2017

The epithelial-mesenchymal transition generates cells with properties of stem cells

1 reference

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30 September 2017

ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis

1 reference

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30 September 2017

Energy metabolism transition in multi-cellular human tumor spheroids.

1 reference

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30 September 2017

Resveratrol inhibits glucose metabolism in human ovarian cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

Reactive oxygen species: a breath of life or death?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

Glucose metabolism and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

Reactive oxygen species in cancer cells: live by the sword, die by the sword.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

Carbohydrate response element binding protein, ChREBP, a transcription factor coupling hepatic glucose utilization and lipid synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

Fatty acid synthase and cancer: new application of an old pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

Redox sensor CtBP mediates hypoxia-induced tumor cell migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

p53 regulates mitochondrial respiration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

Metastasis: a question of life or death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

GenePattern 2.0

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30 September 2017

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

1 reference

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30 September 2017

Opinion: migrating cancer stem cells - an integrated concept of malignant tumour progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

Increased oxidative stress in obesity and its impact on metabolic syndrome

1 reference

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30 September 2017

Why do cancers have high aerobic glycolysis?

1 reference

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30 September 2017

Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4698658

30 September 2017

Applying the principles of stem-cell biology to cancer

1 reference

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30 September 2017

Contribution by different fuels and metabolic pathways to the total ATP turnover of proliferating MCF-7 breast cancer cells.

1 reference

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30 September 2017

Regulation of corepressor function by nuclear NADH.

1 reference

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30 September 2017

Tumor progression and metastasis

1 reference

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30 September 2017

A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance

1 reference

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21 September 2018

Parallel progression of primary tumours and metastases

1 reference

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21 September 2018

Relationship between in vivo chlorzoxazone hydroxylation, hepatic cytochrome P450 2E1 content and liver injury in obese non-alcoholic fatty liver disease patients

1 reference

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21 September 2018

Neither LKB1 nor AMPK are the direct targets of metformin

1 reference

https://pubmed.ncbi.nlm.nih.gov/26725848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty acid synthase (FAS) is a marker of increased risk of recurrence in lung carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/26725848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SREP18669

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26725848%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26725848%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26725848%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

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