(Q36429389)

14 August 2017

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title

Role of IkappaB kinase in tumorigenesis (English)

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14 August 2017

Mickey C-T Hu

1

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14 August 2017

M C Hung

series ordinal

2

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14 August 2017

language of work or name

English

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publication date

1 February 2005

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14 August 2017

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14 August 2017

volume

1

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14 August 2017

issue

1

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14 August 2017

page(s)

67-78

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NF-kappaB family of transcription factors: central regulators of innate and adaptive immune functions.

14 August 2017

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NF-kappaB in cancer: from innocent bystander to major culprit

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NF-kappaB in cancer--a friend turned foe.

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Missing pieces in the NF-kappaB puzzle

21 January 2018

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IkappaB kinases: key regulators of the NF-kappaB pathway

21 January 2018

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Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

21 January 2018

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The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

21 January 2018

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TNF-induced recruitment and activation of the IKK complex require Cdc37 and Hsp90

21 January 2018

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Requirement of Hsp90 activity for IkappaB kinase (IKK) biosynthesis and for constitutive and inducible IKK and NF-kappaB activation.

21 January 2018

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Activation of transcription factor NF-kappaB requires ELKS, an IkappaB kinase regulatory subunit

21 January 2018

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Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

21 January 2018

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IKKalpha controls formation of the epidermis independently of NF-kappaB.

21 January 2018

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Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

21 January 2018

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The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways

21 January 2018

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CK2 Is a C-Terminal IκB Kinase Responsible for NF-κB Activation during the UV Response

21 January 2018

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Different modes of NF-kappaB/Rel activation in pancreatic lobules

21 January 2018

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Dual effect of oxidative stress on NF-kappakB activation in HeLa cells

21 January 2018

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NF-kappaB function in growth control: regulation of cyclin D1 expression and G0/G1-to-S-phase transition

21 January 2018

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NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1.

21 January 2018

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Direct trans-activation of the human cyclin D2 gene by the oncogene product Tax of human T-cell leukemia virus type I.

21 January 2018

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NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

21 January 2018

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Specific protection against breast cancers by cyclin D1 ablation

21 January 2018

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NF-kappaB and cell-cycle regulation: the cyclin connection

21 January 2018

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IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a

21 January 2018

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Efficient adenoviral transfer of NF-kappaB inhibitor sensitizes melanoma to tumor necrosis factor-mediated apoptosis.

21 January 2018

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Overexpression of ErbB2 in cancer and ErbB2-targeting strategies

21 January 2018

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Phosphorylation on tyrosine-15 of p34(Cdc2) by ErbB2 inhibits p34(Cdc2) activation and is involved in resistance to taxol-induced apoptosis.

21 January 2018

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HER-2/neu blocks tumor necrosis factor-induced apoptosis via the Akt/NF-kappaB pathway

21 January 2018

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PIK3CA is implicated as an oncogene in ovarian cancer.

21 January 2018

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Essential role of AKT-1/protein kinase B alpha in PTEN-controlled tumorigenesis

21 January 2018

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The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.

21 January 2018

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The protein kinase B/Akt signalling pathway in human malignancy

21 January 2018

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Regulation of translation initiation by FRAP/mTOR

21 January 2018

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

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Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells

21 January 2018

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HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation

21 January 2018

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Regulation of protein kinase B/Akt-serine 473 phosphorylation by integrin-linked kinase: critical roles for kinase activity and amino acids arginine 211 and serine 343

21 January 2018

1 reference

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A novel form of constitutively active farnesylated Akt1 prevents mammary epithelial cells from anoikis and suppresses chemotherapy-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14796694.1.1.67

Upregulation of IKKalpha/IKKbeta by integrin-linked kinase is required for HER2/neu-induced NF-kappaB antiapoptotic pathway

21 January 2018

1 reference

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Cell cycle and death control: long live Forkheads

21 January 2018

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Forkhead transcription factors: key players in development and metabolism

21 January 2018

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AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

21 January 2018

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Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors

21 January 2018

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Forkhead transcription factors contribute to execution of the mitotic programme in mammals

21 January 2018

1 reference

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Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

21 January 2018

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The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2

21 January 2018

1 reference

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FOXO proteins regulate tumor necrosis factor-related apoptosis inducing ligand expression. Implications for PTEN mutation in prostate cancer

21 January 2018

1 reference

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Angiopoietin-1 modulates endothelial cell function and gene expression via the transcription factor FKHR (FOXO1).

21 January 2018

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21 January 2018

The Hallmarks of Cancer

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Apoptosis in cancer--implications for therapy

21 January 2018

1 reference

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IKKalpha provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14796694.1.1.67

Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14796694.1.1.67

beta-catenin interacts with and inhibits NF-kappa B in human colon and breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14796694.1.1.67

The IKK NF-kappa B system: a treasure trove for drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14796694.1.1.67

Cell adhesion molecules in the development and progression of malignant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14796694.1.1.67

NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14796694.1.1.67

IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14796694.1.1.67

NF-kappaB functions as a tumour promoter in inflammation-associated cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14796694.1.1.67

MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14796694.1.1.67

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14796694.1.1.67

Structure-activity relationship studies of ethyl 2-[(3-methyl-2,5-dioxo(3-pyrrolinyl))amino]-4-(trifluoromethyl)pyrimidine-5-carboxylate: an inhibitor of AP-1 and NF-kappaB mediated gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14796694.1.1.67

BMS-345541 is a highly selective inhibitor of I kappa B kinase that binds at an allosteric site of the enzyme and blocks NF-kappa B-dependent transcription in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14796694.1.1.67

Novel IKK inhibitors: beta-carbolines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14796694.1.1.67

NF-kappa B as a therapeutic target in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14796694.1.1.67

A system for stable expression of short interfering RNAs in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14796694.1.1.67

TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14796694.1.1.67

Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14796694.1.1.67

TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14796694.1.1.67

21 January 2018

Identifiers

DOI

10.1517/14796694.1.1.67

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14 August 2017

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