(Q36438261)

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Vitamin D receptor agonists increase klotho and osteopontin while decreasing aortic calcification in mice with chronic kidney disease fed a high phosphate diet

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Vitamin D receptor agonists increase klotho and osteopontin while decreasing aortic calcification in mice with chronic kidney disease fed a high phosphate diet (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

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0 references

chronic renal insufficiency

1 reference

based on heuristic

inferred from title

6

object named as

Orson W Moe

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

author name string

Wei Ling Lau

1

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Elizabeth M Leaf

2

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Ming Chang Hu

3

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Marc M Takeno

4

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Makoto Kuro-o

5

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Cecilia M Giachelli

7

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

language of work or name

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publication date

29 August 2012

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Kidney International

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Europe PubMed Central

PMC publication ID

14 August 2017

82

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

12

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

1261-1270

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

https://scigraph.springernature.com/pub.10.1038/ki.2012.322

0 references

Vascular Klotho deficiency potentiates the development of human artery calcification and mediates resistance to fibroblast growth factor 23.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

Daily variability in mineral metabolites in CKD and effects of dietary calcium and calcitriol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

FGF23 induces left ventricular hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

Vitamin D receptor controls expression of the anti-aging klotho gene in mouse and human renal cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

Vitamin D status and mortality risk in CKD: a meta-analysis of prospective studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

25-hydroxyvitamin D concentration is inversely associated with serum MMP-9 in a cross-sectional study of African American ESRD patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

Direct effects of phosphate on vascular cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

Fibroblast growth factor 23 is elevated before parathyroid hormone and phosphate in chronic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

Elastin degradation and vascular smooth muscle cell phenotype change precede cell loss and arterial medial calcification in a uremic mouse model of chronic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

Klotho deficiency causes vascular calcification in chronic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

1,25-Dihydroxyvitamin D3-induced aortic calcifications in experimental uremia: up-regulation of osteoblast markers, calcium-transporting proteins and osterix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

The nuclear vitamin D receptor controls the expression of genes encoding factors which feed the "Fountain of Youth" to mediate healthful aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

Ultrastructural analysis of vascular calcifications in uremia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

Effect of paricalcitol and cinacalcet on serum phosphate, FGF-23, and bone in rats with chronic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

Isolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

Vitamin D receptor activators induce an anticalcific paracrine program in macrophages: requirement of osteopontin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

Phosphate feeding induces arterial medial calcification in uremic mice: role of serum phosphorus, fibroblast growth factor-23, and osteopontin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

The emerging role of phosphate in vascular calcification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

Association of oral calcitriol with improved survival in nondialyzed CKD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

Vitamin D receptor activators can protect against vascular calcification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

Elevated phosphorus modulates vitamin D receptor-mediated gene expression in human vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

Regulation of fibroblast growth factor-23 signaling by klotho

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

1alpha,25-Dihydroxyvitamin D3 upregulates FGF23 gene expression in bone: the final link in a renal-gastrointestinal-skeletal axis that controls phosphate transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

Circulating FGF-23 is regulated by 1alpha,25-dihydroxyvitamin D3 and phosphorus in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

Klotho, a gene related to a syndrome resembling human premature aging, functions in a negative regulatory circuit of vitamin D endocrine system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

Survival of patients undergoing hemodialysis with paricalcitol or calcitriol therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

Phosphate regulation of vascular smooth muscle cell calcification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

Warfarin-induced artery calcification is accelerated by growth and vitamin D

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

Calcification of vascular smooth muscle cell cultures: inhibition by osteopontin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

Association of serum phosphorus and calcium x phosphate product with mortality risk in chronic hemodialysis patients: a national study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

30 September 2017

Klotho is a substrate for alpha-, beta- and gamma-secretase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

28 June 2018

The effect of calcitriol, paricalcitol, and a calcimimetic on extraosseous calcifications in uremic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

28 June 2018

Differential effects of vitamin D analogs on vascular calcification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

28 June 2018

Determination of the elastin content of tissues by measuring desmosine and isodesmosine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

28 June 2018

Upregulation of matrix metalloproteinase-2 in the arterial vasculature contributes to stiffening and vasomotor dysfunction in patients with chronic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

21 September 2018

Role of phosphorus and vitamin D analogs in the pathogenesis of vascular calcification.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

21 September 2018

Genetic dissection of phosphate- and vitamin D-mediated regulation of circulating Fgf23 concentrations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

21 September 2018

Activated injectable vitamin D and hemodialysis survival: a historical cohort study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

21 September 2018

Immunohistochemical localization of Klotho protein in brain, kidney, and reproductive organs of mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

21 September 2018

Serum phosphate levels and mortality risk among people with chronic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

21 September 2018

Human vascular smooth muscle cells undergo vesicle-mediated calcification in response to changes in extracellular calcium and phosphate concentrations: a potential mechanism for accelerated vascular calcification in ESRD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

21 September 2018

Efficacy of 19-Nor-1,25-(OH)2D2 in the prevention and treatment of hyperparathyroid bone disease in experimental uremia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

21 September 2018

Surface imaging microscopy, an automated method for visualizing whole embryo samples in three dimensions at high resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

21 September 2018

Sevelamer attenuates the progression of coronary and aortic calcification in hemodialysis patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

21 September 2018

Differential effects of 19-nor-1,25-dihydroxyvitamin D(2) and 1,25-dihydroxyvitamin D(3) on intestinal calcium and phosphate transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

21 September 2018

Smooth muscle cell phenotypic transition associated with calcification: upregulation of Cbfa1 and downregulation of smooth muscle lineage markers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

21 September 2018

Severely reduced production of klotho in human chronic renal failure kidney.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

21 September 2018

Relations of Serum Phosphorus and Calcium Levels to the Incidence of Cardiovascular Disease in the Community

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511664

4 December 2018

Effect of paricalcitol and calcitriol on aortic wall remodeling in uninephrectomized ApoE knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22932118

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The progression of aging in klotho mutant mice can be modified by dietary phosphorus and zinc

1 reference

https://pubmed.ncbi.nlm.nih.gov/22932118

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1,25-Dihydroxyvitamin D3 increases in vitro vascular calcification by modulating secretion of endogenous parathyroid hormone-related peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/22932118

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mortality risk among hemodialysis patients receiving different vitamin D analogs

1 reference

https://pubmed.ncbi.nlm.nih.gov/22932118

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calciotropic hormones and arterial physiology: "D"-lightful insights

1 reference

https://pubmed.ncbi.nlm.nih.gov/22932118

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mortality effect of coronary calcification and phosphate binder choice in incident hemodialysis patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/22932118

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential effects of vitamin D receptor activators on vascular calcification in uremic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/22932118

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral active vitamin D is associated with improved survival in hemodialysis patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/22932118

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of FGF-23 in CKD-MBD and cardiovascular disease: friend or foe?

1 reference

https://pubmed.ncbi.nlm.nih.gov/22932118

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/KI.2012.322

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

ResearchGate publication ID

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