(Q36438769)

14 August 2017

1 reference

title

Exploiting pathogenic Escherichia coli to model transmembrane receptor signalling (English)

1 reference

14 August 2017

0 references

transmembrane protein

0 references

author name string

Richard D Hayward

1

1 reference

14 August 2017

John M Leong

2

1 reference

14 August 2017

Vassilis Koronakis

3

1 reference

14 August 2017

Kenneth G Campellone

4

1 reference

14 August 2017

language of work or name

English

0 references

publication date

1 May 2006

1 reference

Nature Reviews Microbiology

14 August 2017

published in

1 reference

14 August 2017

volume

4

1 reference

14 August 2017

issue

5

1 reference

14 August 2017

page(s)

358-370

1 reference

https://scigraph.springernature.com/pub.10.1038/nrmicro1391

14 August 2017

exact match

0 references

cites work

Bacterial invasion: the paradigms of enteroinvasive pathogens

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Structural mimicry in bacterial virulence

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Diarrheagenic Escherichia coli

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

The role of the eae gene of enterohemorrhagic Escherichia coli in intimate attachment in vitro and in a porcine model

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Role of the eaeA gene in experimental enteropathogenic Escherichia coli infection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Citrobacter rodentium translocated intimin receptor (Tir) is an essential virulence factor needed for actin condensation, intestinal colonization and colonic hyperplasia in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Actin and alpha-actinin dynamics in the adhesion and motility of EPEC and EHEC on host cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Actin dynamics: growth from dendritic branches.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Cellular motility driven by assembly and disassembly of actin filaments

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Focal adhesion and actin dynamics: a place where kinases and proteases meet to promote invasion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

WASp in immune-system organization and function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Cellular control of actin nucleation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Signalling to actin assembly via the WASP (Wiskott-Aldrich syndrome protein)-family proteins and the Arp2/3 complex

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Regulation of actin filament network formation through ARP2/3 complex: activation by a diverse array of proteins.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Mechanisms of WASp-mediated hematologic and immunologic disease.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Regulation of actin dynamics by WASP and WAVE family proteins.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Critical conformational changes in the Arp2/3 complex are induced by nucleotide and nucleation promoting factor.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Integration of multiple signals through cooperative regulation of the N-WASP-Arp2/3 complex

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

A complex of N-WASP and WIP integrates signalling cascades that lead to actin polymerization

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

WIP regulates N-WASP-mediated actin polymerization and filopodium formation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

The Wiskott-Aldrich syndrome protein-interacting protein (WIP) binds to the adaptor protein Nck

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

The essential role of profilin in the assembly of actin for microspike formation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Toca-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complex

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Sustained activation of N-WASP through phosphorylation is essential for neurite extension

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

GRB2 links signaling to actin assembly by enhancing interaction of neural Wiskott-Aldrich syndrome protein (N-WASp) with actin-related protein (ARP2/3) complex

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Nck and phosphatidylinositol 4,5-bisphosphate synergistically activate actin polymerization through the N-WASP-Arp2/3 pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Erk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASP

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Phosphorylation of the WASP-VCA domain increases its affinity for the Arp2/3 complex and enhances actin polymerization by WASP

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Enterohaemorrhagic and enteropathogenic Escherichia coli use different mechanisms for actin pedestal formation that converge on N-WASP.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Enteropathogenic E. coli acts through WASP and Arp2/3 complex to form actin pedestals

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Actin pedestal formation by enteropathogenic Escherichia coli and intracellular motility of Shigella flexneri are abolished in N-WASP-defective cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Small GTP-binding proteins of the Rho- and Ras-subfamilies are not involved in the actin rearrangements induced by attaching and effacing Escherichia coli

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

A genetic locus of enteropathogenic Escherichia coli necessary for the production of attaching and effacing lesions on tissue culture cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

A cloned pathogenicity island from enteropathogenic Escherichia coli confers the attaching and effacing phenotype on E. coli K-12.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

The complete sequence of the locus of enterocyte effacement (LEE) from enteropathogenic Escherichia coli E2348/69.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Initial binding of Shiga toxin-producing Escherichia coli to host cells and subsequent induction of actin rearrangements depend on filamentous EspA-containing surface appendages

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

A novel EspA-associated surface organelle of enteropathogenic Escherichia coli involved in protein translocation into epithelial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Supermolecular structure of the enteropathogenic Escherichia coli type III secretion system and its direct interaction with the EspA-sheath-like structure

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

EPEC's weapons of mass subversion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Enteropathogenic and enterohemorrhagic Escherichia coli infections: translocation, translocation, translocation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

A pathogenic bacterium triggers epithelial signals to form a functional bacterial receptor that mediates actin pseudopod formation.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Enteropathogenic E. coli (EPEC) transfers its receptor for intimate adherence into mammalian cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

EspE, a novel secreted protein of attaching and effacing bacteria, is directly translocated into infected host cells, where it appears as a tyrosine-phosphorylated 90 kDa protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Host protein interactions with enteropathogenic Escherichia coli (EPEC): 14-3-3tau binds Tir and has a role in EPEC-induced actin polymerization

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Enteropathogenic E. coli translocated intimin receptor, Tir, interacts directly with alpha-actinin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Interaction of the enteropathogenic Escherichia coli protein, translocated intimin receptor (Tir), with focal adhesion proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Cortactin is necessary for F-actin accumulation in pedestal structures induced by enteropathogenic Escherichia coli infection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Recruitment of cytoskeletal and signaling proteins to enteropathogenic and enterohemorrhagic Escherichia coli pedestals

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Tails of two Tirs: actin pedestal formation by enteropathogenic E. coli and enterohemorrhagic E. coli O157:H7.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

A tyrosine-phosphorylated 12-amino-acid sequence of enteropathogenic Escherichia coli Tir binds the host adaptor protein Nck and is required for Nck localization to actin pedestals

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Enteropathogenic E. coli Tir binds Nck to initiate actin pedestal formation in host cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Phosphorylation of tyrosine 474 of the enteropathogenic Escherichia coli (EPEC) Tir receptor molecule is essential for actin nucleating activity and is preceded by additional host modifications

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Phosphorylation of the enteropathogenic E. coli receptor by the Src-family kinase c-Fyn triggers actin pedestal formation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Enteropathogenic Escherichia coli use redundant tyrosine kinases to form actin pedestals.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Inducible clustering of membrane-targeted SH3 domains of the adaptor protein Nck triggers localized actin polymerization

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

EspFU is a translocated EHEC effector that interacts with Tir and N-WASP and promotes Nck-independent actin assembly

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Clustering of Nck by a 12-residue Tir phosphopeptide is sufficient to trigger localized actin assembly

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Nck-independent actin assembly is mediated by two phosphorylated tyrosines within enteropathogenic Escherichia coli Tir.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Surfing pathogens and the lessons learned for actin polymerization.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Actin-based motility of vaccinia virus mimics receptor tyrosine kinase signalling.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Disabling poxvirus pathogenesis by inhibition of Abl-family tyrosine kinases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Grb2 and Nck act cooperatively to promote actin-based motility of vaccinia virus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Intimin and the host cell--is it bound to end in Tir(s)?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Cell surface-localized nucleolin is a eukaryotic receptor for the adhesin intimin-gamma of enterohemorrhagic Escherichia coli O157:H7.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

The Tir-binding region of enterohaemorrhagic Escherichia coli intimin is sufficient to trigger actin condensation after bacterial-induced host cell signalling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Crystal structure of enteropathogenic Escherichia coli intimin-receptor complex

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Structural basis for recognition of the translocated intimin receptor (Tir) by intimin from enteropathogenic Escherichia coli

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Crystal structure of invasin: a bacterial integrin-binding protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Signal transduction: receptor clusters as information processing arrays

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Receptor clustering and transmembrane signaling in T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Self-association of EPEC intimin mediated by the beta-barrel-containing anchor domain: a role in clustering of the Tir receptor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

A region of the Yersinia pseudotuberculosis invasin protein enhances integrin-mediated uptake into mammalian cells and promotes self-association

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Clusters of glycolipid and glycosylphosphatidylinositol-anchored proteins in lymphoid cells: accumulation of actin regulated by local tyrosine phosphorylation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

All roads lead to actin: the intimate relationship between TCR signaling and the cytoskeleton

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Src-family kinases: rheostats of immune cell signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Mechanism of recruitment of WASP to the immunological synapse and of its activation following TCR ligation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Integrins: versatile integrators of extracellular signals

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

TCR signal initiation machinery is pre-assembled and activated in a subset of membrane rafts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Requirement for Abl kinases in T cell receptor signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

The interplay between Src and integrins in normal and tumor biology

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Integrin-actin interactions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

SRC mediates a switch from microtubule- to actin-based motility of vaccinia virus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Abl collaborates with Src family kinases to stimulate actin-based motility of vaccinia virus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

How do Abl family kinases regulate cell shape and movement?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

TccP is an enterohaemorrhagic Escherichia coli O157:H7 type III effector protein that couples Tir to the actin-cytoskeleton

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Comparison of Tir from enterohemorrahgic and enteropathogenic Escherichia coli strains: two homologues with distinct intracellular properties.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Enterohaemorrhagic and enteropathogenic Escherichia coli use a different Tir-based mechanism for pedestal formation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

The enterohaemorrhagic Escherichia coli (serotype O157:H7) Tir molecule is not functionally interchangeable for its enteropathogenic E. coli (serotype O127:H6) homologue

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Comparative analysis of EspF from enteropathogenic and enterohemorrhagic Escherichia coli in alteration of epithelial barrier function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Activation of the CDC42 effector N-WASP by the Shigella flexneri IcsA protein promotes actin nucleation by Arp2/3 complex and bacterial actin-based motility

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Neural Wiskott-Aldrich syndrome protein is implicated in the actin-based motility of Shigella flexneri

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Cdc42 facilitates invasion but not the actin-based motility of Shigella

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Rho family GTPase Cdc42 is essential for the actin-based motility of Shigella in mammalian cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

N-WASP deficiency reveals distinct pathways for cell surface projections and microbial actin-based motility

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Neural Wiskott-Aldrich syndrome protein (N-WASP) is the specific ligand for Shigella VirG among the WASP family and determines the host cell type allowing actin-based spreading

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Focal adhesion kinase regulation of N-WASP subcellular localization and function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Contingent phosphorylation/dephosphorylation provides a mechanism of molecular memory in WASP.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Structure of Cdc42 in complex with the GTPase-binding domain of the 'Wiskott-Aldrich syndrome' protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Cell migration: Rho GTPases lead the way

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Protein-tyrosine kinase and GTPase signals cooperate to phosphorylate and activate Wiskott-Aldrich syndrome protein (WASP)/neuronal WASP

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Distribution of tccP in clinical enterohemorrhagic and enteropathogenic Escherichia coli isolates

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Regulation of WASP/WAVE proteins: making a long story short

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Drosophila Spire is an actin nucleation factor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

The formins: active scaffolds that remodel the cytoskeleton

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Identification of a bacterial type III effector family with G protein mimicry functions.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

Enterohemorrhagic Escherichia coli O157:H7 produces Tir, which is translocated to the host cell membrane but is not tyrosine phosphorylated.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1391

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRMICRO1391

1 reference

Dimensions Publication ID

14 August 2017

1007903470

0 references

1 reference