(Q36455974)

14 August 2017

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title

Regulatory T cells in human disease and their potential for therapeutic manipulation (English)

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14 August 2017

Leonie S Taams

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Catherine M. Hawrylowicz

object named as

Catherine M Hawrylowicz

6

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author name string

Donald B Palmer

2

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14 August 2017

Arne N Akbar

3

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14 August 2017

Douglas S Robinson

4

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14 August 2017

Zarin Brown

5

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14 August 2017

1 May 2006

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14 August 2017

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14 August 2017

118

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14 August 2017

1

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14 August 2017

1-9

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A history of prostate cancer treatment

14 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Regulatory T cells in the control of immune pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Type 1 T regulatory cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Potential role of interleukin-10-secreting regulatory T cells in allergy and asthma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Transforming growth factor-beta in T-cell biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Foxp3 and natural regulatory T cells: key to a cell lineage?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Expression of FOXP3 mRNA is not confined to CD4+CD25+ T regulatory cells in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Defective suppressor function of human CD4+ CD25+ regulatory T cells in autoimmune polyglandular syndrome type II

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Dysfunctional blood and target tissue CD4+CD25high regulatory T cells in psoriasis: mechanism underlying unrestrained pathogenic effector T cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Functional defect of regulatory CD4(+)CD25+ T cells in the thymus of patients with autoimmune myasthenia gravis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

CD4+CD25bright regulatory T cells actively regulate inflammation in the joints of patients with the remitting form of juvenile idiopathic arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

CD25brightCD4+ regulatory T cells are enriched in inflamed joints of patients with chronic rheumatic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Coexpression of CD25 and CD27 identifies FoxP3+ regulatory T cells in inflamed synovia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Relation of CD4+CD25+ regulatory T-cell suppression of allergen-driven T-cell activation to atopic status and expression of allergic disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Defective suppression of Th2 cytokines by CD4CD25 regulatory T cells in birch allergics during birch pollen season

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Human CD4+CD25+ T cells derived from the majority of atopic donors are able to suppress TH1 and TH2 cytokine production

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Antigen-specific T cell suppression by human CD4+CD25+ regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Human CD25+ regulatory T cells maintain immune tolerance to nickel in healthy, nonallergic individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Cow's milk-specific T-cell reactivity of children with and without persistent cow's milk allergy: key role for IL-10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

A defect in corticosteroid-induced IL-10 production in T lymphocytes from corticosteroid-resistant asthmatic patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Allergen-responsive CD4+CD25+ regulatory T cells in children who have outgrown cow's milk allergy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Tregs and allergic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Regulatory T cells: friend or foe in immunity to infection?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Natural regulatory T cells in infectious disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Helicobacter pylori-specific CD4+ CD25high regulatory T cells suppress memory T-cell responses to H. pylori in infected individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Mucosal FOXP3-expressing CD4+ CD25high regulatory T cells in Helicobacter pylori-infected patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Allergy, parasites, and the hygiene hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Antigen-specific T regulatory-1 cells are associated with immunosuppression in a chronic helminth infection (onchocerciasis).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

An immunomodulatory role for CD4(+)CD25(+) regulatory T lymphocytes in hepatitis C virus infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Regulatory T cells contribute to the impaired immune response in patients with chronic hepatitis B virus infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Human CD4+ CD25+ regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Human immunodeficiency virus-driven expansion of CD4+CD25+ regulatory T cells, which suppress HIV-specific CD4 T-cell responses in HIV-infected patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Depletion of regulatory T cells in HIV infection is associated with immune activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

CD25(+)CD4(+) regulatory T cells from the peripheral blood of asymptomatic HIV-infected individuals regulate CD4(+) and CD8(+) HIV-specific T cell immune responses in vitro and are associated with favorable clinical markers of disease status

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Foxp3 expressing CD4+CD25(high) regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Increased populations of regulatory T cells in peripheral blood of patients with hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Regulatory T cells in transplantation tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Regulatory T cells and organ transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

High levels of interleukin 10 production in vivo are associated with tolerance in SCID patients transplanted with HLA mismatched hematopoietic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Cytokine responses to cardiopulmonary bypass: lessons learned from cardiac transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Glucocorticoids upregulate FOXP3 expression and regulatory T cells in asthma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Fluticasone propionate increases CD4CD25 T regulatory cell suppression of allergen-stimulated CD4CD25 T cells by an IL-10-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Regulatory T cells induced by 1 alpha,25-dihydroxyvitamin D3 and mycophenolate mofetil treatment mediate transplantation tolerance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Interleukin-10-secreting "regulatory" T cells induced by glucocorticoids and beta2-agonists.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Reversing the defective induction of IL-10-secreting regulatory T cells in glucocorticoid-resistant asthma patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Large-scale in vitro expansion of polyclonal human CD4(+)CD25high regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

In vitro-expanded human CD4(+)CD25(+) T-regulatory cells can markedly inhibit allogeneic dendritic cell-stimulated MLR cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Induction of allopeptide-specific human CD4+CD25+ regulatory T cells ex vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Dendritic cells as a tool to induce anergic and regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Severe anaphylactic reactions to glutamic acid decarboxylase (GAD) self peptides in NOD mice that spontaneously develop autoimmune type 1 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Epitope-specific immunotherapy induces immune deviation of proinflammatory T cells in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

T cell epitope immunotherapy induces a CD4+ T cell population with regulatory activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

An anti-CD45RO/RB monoclonal antibody modulates T cell responses via induction of apoptosis and generation of regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Cutting edge: cure of colitis by CD4+CD25+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782265

Peptide-based therapeutic vaccines for allergic and autoimmune diseases

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782265

Defective suppressor function in CD4(+)CD25(+) T-cells from patients with type 1 diabetes.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782265

IL-10-producing and naturally occurring CD4+ Tregs: limiting collateral damage

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782265

Suppression of HCV-specific T cells without differential hierarchy demonstrated ex vivo in persistent HCV infection

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782265

Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25– T cells

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782265

Increase of regulatory T cells in the peripheral blood of cancer patients.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782265

CD4+ CD25+ suppressor T cells: more questions than answers

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782265

Induction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunity

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782265

Role of interleukin 10 in specific immunotherapy

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782265

Insect venom immunotherapy induces interleukin-10 production and a Th2-to-Th1 shift, and changes surface marker expression in venom-allergic subjects.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782265

CD4+ CD25+ T cells with the phenotypic and functional characteristics of regulatory T cells are enriched in the synovial fluid of patients with rheumatoid arthritis

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782265

CD4(+)CD25(+) regulatory T cells in rheumatoid arthritis: differences in the presence, phenotype, and function between peripheral blood and synovial fluid

21 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782265

Immunosuppressive regulatory T cells are abundant in the reactive lymphocytes of Hodgkin lymphoma

21 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782265

Efficient expansion of regulatory T cells in vitro and in vivo with a CD28 superagonist

21 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782265

Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma

21 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782265

Cutting edge: Regulatory T cells from lung cancer patients directly inhibit autologous T cell proliferation

21 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782265

IL-10–producing and naturally occurring CD4+ Tregs: limiting collateral damage

21 October 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Induction of a non-encephalitogenic type 2 T helper-cell autoimmune responsein multiple sclerosis after administration of an altered peptide ligand ina placebo-controlled, randomized phase II trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2006.02348.X

Nucleosome-specific regulatory T cells engineered by triple gene transfer suppress a systemic autoimmune disease

21 January 2018

1 reference

12 December 2020

Cat allergen peptide immunotherapy reduces CD4(+) T cell responses to cat allergen but does not alter suppression by CD4(+) CD25(+) T cells: a double-blind placebo-controlled study

1 reference

12 December 2020

Induction and mechanism of action of transforming growth factor-beta-secreting Th3 regulatory cells

1 reference

12 December 2020

Exposure to myeloma cell lysates affects the immune competence of dendritic cells and favors the induction of Tr1-like regulatory T cells

1 reference

12 December 2020

Glucocorticoids drive human CD8(+) T cell differentiation towards a phenotype with high IL-10 and reduced IL-4, IL-5 and IL-13 production

1 reference

12 December 2020

10.1111/J.1365-2567.2006.02348.X

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DOI

1 reference

14 August 2017

0 references

1 reference