(Q36466825)

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The exosome secretory pathway transports amyloid precursor protein carboxyl-terminal fragments from the cell into the brain extracellular space

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scholarly article

1 reference

Europe PubMed Central

14 August 2017

The exosome secretory pathway transports amyloid precursor protein carboxyl-terminal fragments from the cell into the brain extracellular space (English)

1 reference

Europe PubMed Central

14 August 2017

author name string

Rocio Perez-Gonzalez

1

1 reference

Europe PubMed Central

14 August 2017

Sebastien A Gauthier

2

1 reference

Europe PubMed Central

14 August 2017

Asok Kumar

3

1 reference

Europe PubMed Central

14 August 2017

Efrat Levy

4

1 reference

Europe PubMed Central

14 August 2017

language of work or name

0 references

publication date

5 November 2012

1 reference

Europe PubMed Central

14 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

14 August 2017

287

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Europe PubMed Central

14 August 2017

51

1 reference

Europe PubMed Central

14 August 2017

43108-43115

1 reference

Europe PubMed Central

14 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3522305/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Inhibition of γ-secretase worsens memory deficits in a genetically congruous mouse model of Danish dementia

1 reference

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30 September 2017

Novel GαS-protein signaling associated with membrane-tethered amyloid precursor protein intracellular domain.

1 reference

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30 September 2017

β- but not γ-secretase proteolysis of APP causes synaptic and memory deficits in a mouse model of dementia

1 reference

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30 September 2017

Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease

1 reference

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A filtration-based protocol to isolate human plasma membrane-derived vesicles and exosomes from blood plasma.

1 reference

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30 September 2017

Exosomes as intercellular signalosomes and pharmacological effectors.

1 reference

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30 September 2017

Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission.

1 reference

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30 September 2017

Statins promote the degradation of extracellular amyloid {beta}-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion

1 reference

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Cell-produced alpha-synuclein is secreted in a calcium-dependent manner by exosomes and impacts neuronal survival

1 reference

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HIV and mature dendritic cells: Trojan exosomes riding the Trojan horse?

1 reference

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30 September 2017

Cystatin C protects neuronal cells from amyloid-beta-induced toxicity

1 reference

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30 September 2017

Alzheimer's-related endosome dysfunction in Down syndrome is Abeta-independent but requires APP and is reversed by BACE-1 inhibition.

1 reference

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30 September 2017

Insulin-degrading enzyme sorting in exosomes: a secretory pathway for a key brain amyloid-beta degrading protease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522305

30 September 2017

The morphology and biochemistry of nanostructures provide evidence for synthesis and signaling functions in human cerebrospinal fluid

1 reference

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30 September 2017

Proteomic profiling of exosomes: current perspectives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522305

30 September 2017

Functional role of N-glycosylation from ADAM10 in processing, localization and activity of the enzyme.

1 reference

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1 reference

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The role of exosomes in the processing of proteins associated with neurodegenerative diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522305

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Exosomal transfer of proteins and RNAs at synapses in the nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522305

30 September 2017

Alkalizing drugs induce accumulation of amyloid precursor protein by-products in luminal vesicles of multivesicular bodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522305

30 September 2017

Exosomes: from biogenesis and secretion to biological function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522305

30 September 2017

Alzheimer's disease beta-amyloid peptides are released in association with exosomes

1 reference

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30 September 2017

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30 September 2017

Amyloidogenic processing of beta-amyloid precursor protein in intracellular compartments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522305

30 September 2017

A protein's final ESCRT.

1 reference

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30 September 2017

Subcellular topography of neuronal Abeta peptide in APPxPS1 transgenic mice

1 reference

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30 September 2017

Deciphering the molecular basis of memory failure in Alzheimer's disease

1 reference

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30 September 2017

Identification and proteomic profiling of exosomes in human urine

1 reference

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30 September 2017

Exosomes: endosomal-derived vesicles shipping extracellular messages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522305

30 September 2017

Cells release prions in association with exosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522305

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A new and rapid colorimetric determination of acetylcholinesterase activity

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30 September 2017

The Trojan exosome hypothesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522305

30 September 2017

In vitro characterization of conditions for amyloid-beta peptide oligomerization and fibrillogenesis

1 reference

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Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology

1 reference

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Exosomes: composition, biogenesis and function

1 reference

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The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

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30 September 2017

Calpain activity regulates the cell surface distribution of amyloid precursor protein. Inhibition of calpains enhances endosomal generation of beta-cleaved C-terminal APP fragments

1 reference

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The exosome pathway in K562 cells is regulated by Rab11.

1 reference

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30 September 2017

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Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

1 reference

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Alzheimer's disease: genes, proteins, and therapy

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Targeting small Abeta oligomers: the solution to an Alzheimer's disease conundrum?

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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

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Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes)

1 reference

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30 September 2017

Neuropathological stageing of Alzheimer-related changes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522305

30 September 2017

The molecular pathology of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522305

30 September 2017

Inhibition of gamma-secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522305

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Exosomes are released by cultured cortical neurones.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522305

21 September 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522305

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Transmission of circulating cell-free AA amyloid oligomers in exosomes vectors via a prion-like mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/23129776

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1 reference

https://pubmed.ncbi.nlm.nih.gov/23129776

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.404467

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

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