(Q36477935)

14 August 2017

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title

Mediators and modulators of pulmonary arterial hypertension (English)

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14 August 2017

main subject

arterial hypertension

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author name string

Sami I Said

series ordinal

1

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14 August 2017

publication date

12 May 2006

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American Journal of Physiology - Lung Cellular and Molecular Physiology

14 August 2017

published in

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14 August 2017

volume

291

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14 August 2017

issue

4

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14 August 2017

page(s)

L547-58

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Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of type II bone morphogenetic protein receptor

14 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Medical therapy for pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Sitaxsentan therapy for pulmonary arterial hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Pituitary adenylate cyclase-activating polypeptide stimulates cardiodilatin/atrial natriuretic peptide (CDD/ANP-(99-126) secretion from cultured neonatal rat myocardiocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

BMPR-II heterozygous mice have mild pulmonary hypertension and an impaired pulmonary vascular remodeling response to prolonged hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Role of transforming growth factor beta in human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Pituitary adenylate cyclase activating peptides relax human pulmonary arteries by opening of KATP and KCa channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Cell-based gene transfer of vascular endothelial growth factor attenuates monocrotaline-induced pulmonary hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

The induction of nitric oxide-mediated relaxation of human isolated pulmonary arteries by PACAP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebo-controlled study

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Dominant negative mutation of the TGF-beta receptor blocks hypoxia-induced pulmonary vascular remodeling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

ET(A) and ET(B) receptors modulate the proliferation of human pulmonary artery smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide inhibit CBP-NF-kappaB interaction in activated microglia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Cardioprotective role of the VIP signaling system

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Attenuated hypoxic pulmonary hypertension in mice lacking the 5-hydroxytryptamine transporter gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Serotonin transporter overexpression is responsible for pulmonary artery smooth muscle hyperplasia in primary pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Genetics of pulmonary arterial hypertension: current and future implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Thromboxane inhibition reduces an early stage of chronic hypoxia-induced pulmonary hypertension in piglets

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Direct signaling by the BMP type II receptor via the cytoskeletal regulator LIMK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Ambrisentan therapy for pulmonary arterial hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Sildenafil citrate therapy for pulmonary arterial hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Sildenafil increased exercise capacity during hypoxia at low altitudes and at Mount Everest base camp: a randomized, double-blind, placebo-controlled crossover trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Imatinib for the treatment of pulmonary arterial hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Expression of endothelin-1 in the lungs of patients with pulmonary hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Gene transfer of vascular endothelial growth factor reduces bleomycin-induced pulmonary hypertension in immature rabbits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

The effects of vasoactive intestinal peptide on monocrotaline induced pulmonary hypertensive rabbits following cardiopulmonary bypass: a comparative study with isoproteronol and nitroglycerine

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

TGF-beta signalling from cell membrane to nucleus through SMAD proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Drug treatment of pulmonary arterial hypertension: current and future agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Prostacyclin receptor-dependent modulation of pulmonary vascular remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Treatment of pulmonary arterial hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Molecular and cellular basis of pulmonary vascular remodeling in pulmonary hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

BMP4 inhibits proliferation and promotes myocyte differentiation of lung fibroblasts via Smad1 and JNK pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Estrogen upregulates cyclooxygenase-1 gene expression in ovine fetal pulmonary artery endothelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Pulmonary hemodynamic responses to brain natriuretic peptide and sildenafil in patients with pulmonary arterial hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Treatment of newborn rats with a VEGF receptor inhibitor causes pulmonary hypertension and abnormal lung structure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Vasoactive intestinal polypeptide and pituitary adenylate cyclase-activating polypeptides stimulate mitogen-activated protein kinase in the pituitary cell line GH4C1 by a 3',5'-cyclic adenosine monophosphate pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Current treatment strategies for pulmonary arterial hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Serotonin increases susceptibility to pulmonary hypertension in BMPR2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Mutations of the TGF-beta type II receptor BMPR2 in pulmonary arterial hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Investigation of Second Genetic Hits at the BMPR2 Locus as a Modulator of Disease Progression in Familial Pulmonary Arterial Hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Genetic association of the serotonin transporter in pulmonary arterial hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

BMPR2 haploinsufficiency as the inherited molecular mechanism for primary pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Overexpression of the 5-hydroxytryptamine transporter gene: effect on pulmonary hemodynamics and hypoxia-induced pulmonary hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

TGF-beta signalling through the Smad pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

TGFbeta signaling in growth control, cancer, and heritable disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Adrenomedullin can protect against pulmonary vascular remodeling induced by hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Survival in primary pulmonary hypertension: the impact of epoprostenol therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Survival with first-line bosentan in patients with primary pulmonary hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Divergence and convergence of TGF-beta/BMP signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

BMP receptor signaling: transcriptional targets, regulation of signals, and signaling cross-talk

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Pilot study of losartan for pulmonary hypertension in chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Adrenomedullin in the treatment of pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Effects of adrenomedullin inhalation on hemodynamics and exercise capacity in patients with idiopathic pulmonary arterial hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Repeated inhalation of adrenomedullin ameliorates pulmonary hypertension and survival in monocrotaline rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Pulmonary hypertension in a GTP-cyclohydrolase 1-deficient mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Pulmonary vasodilator responses to vasoactive intestinal peptide in the cat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Treatment of primary pulmonary hypertension -- the next generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Pulmonary arterial hypertension: future directions: report of a National Heart, Lung and Blood Institute/Office of Rare Diseases workshop

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Genetic basis of pulmonary arterial hypertension: current understanding and future directions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Mutation in the gene for bone morphogenetic protein receptor II as a cause of primary pulmonary hypertension in a large kindred

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Functional heterogeneity of bone morphogenetic protein receptor-II mutants found in patients with primary pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Simvastatin attenuates smooth muscle neointimal proliferation and pulmonary hypertension in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Simvastatin rescues rats from fatal pulmonary hypertension by inducing apoptosis of neointimal smooth muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Adrenomedullin inhibits ovalbumin-induced bronchoconstriction and airway microvascular leakage in guinea-pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Inhaled iloprost for severe pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide attenuate the cigarette smoke extract-induced apoptotic death of rat alveolar L2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Pulmonary hypertension and right heart failure in pituitary adenylate cyclase-activating polypeptide type I receptor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Vasoactive intestinal peptide as a new drug for treatment of primary pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Transforming growth factor-beta and ciliary neurotrophic factor synergistically induce vasoactive intestinal peptide gene expression through the cooperation of Smad, STAT, and AP-1 sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Effects of menstrual cycle and oral contraceptive use on calf venous compliance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Therapy of pulmonary hypertension: the evolution from vasodilators to antiproliferative agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Functional analysis of bone morphogenetic protein type II receptor mutations underlying primary pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Vasoactive peptides and the pulmonary circulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Pathways of inflammation and cell death in the lung: modulation by vasoactive intestinal peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

The multiple mediators of neurogenic smooth muscle relaxation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Enhancement of systemic and pulmonary vasoconstriction by beta-amyloid peptides and its suppression by vasoactive intestinal peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Reversal of experimental pulmonary hypertension by PDGF inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Clinical classification of pulmonary hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Continuous subcutaneous infusion of treprostinil, a prostacyclin analogue, in patients with pulmonary arterial hypertension: a double-blind, randomized, placebo-controlled trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Long-term intravenous epoprostenol infusion in primary pulmonary hypertension: prognostic factors and survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Human prostacyclin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Increased susceptibility to pulmonary hypertension in heterozygous BMPR2-mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Recent insights into the pathogenesis and therapeutics of pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Pulmonary vasoconstriction and hypertension in mice with targeted disruption of the endothelial nitric oxide synthase (NOS 3) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Molecular and cellular determinants of lung endothelial cell heterogeneity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Increased plasma endothelin-1 in pulmonary hypertension: marker or mediator of disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Adaptative increase of ornithine production and decrease of ammonia metabolism in rat colonocytes after hyperproteic diet ingestion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

A bradykinin antagonist and a caspase inhibitor prevent severe pulmonary hypertension in a rat model

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Prostanoids and phosphodiesterase inhibitors in experimental pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-beta family

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Recombinant human relaxin reduces hypoxic pulmonary hypertension in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Pituitary adenylate cyclase-activating peptide (PACAP), a new vasoactive intestinal peptide (VIP)-like peptide in the respiratory tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Pulmonary hypertension in transgenic mice expressing a dominant-negative BMPRII gene in smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Serotonin transporter polymorphisms in familial and idiopathic pulmonary arterial hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Adrenomedullin and adrenomedullin binding protein-1 downregulate TNF-alpha in macrophage cell line and rat Kupffer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Dysfunctional Smad Signaling Contributes to Abnormal Smooth Muscle Cell Proliferation in Familial Pulmonary Arterial Hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Long-lasting smooth-muscle relaxation by a novel PACAP analogue in human bronchi

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

PDGF stimulates pulmonary vascular smooth muscle cell proliferation by upregulating TRPC6 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Pathogenesis of pulmonary arterial hypertension: the need for multiple hits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

One hundred years of research in the pathogenesis of pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Pulmonary Arterial Hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00546.2005

10.1152/AJPLUNG.00546.2005

21 January 2018

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DOI

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14 August 2017

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