(Q36481128)

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Adipocyte-Specific Hypoxia-Inducible Factor 2α Deficiency Exacerbates Obesity-Induced Brown Adipose Tissue Dysfunction and Metabolic Dysregulation

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scholarly article

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Europe PubMed Central

14 August 2017

Adipocyte-Specific Hypoxia-Inducible Factor 2α Deficiency Exacerbates Obesity-Induced Brown Adipose Tissue Dysfunction and Metabolic Dysregulation (English)

1 reference

Europe PubMed Central

14 August 2017

Endothelial PAS domain protein 1

1 reference

GOA release 2020-03-11

positive regulation of cold-induced thermogenesis

1 reference

GOA release 2020-03-11

Endothelial PAS domain protein 1

1 reference

GOA release 2020-03-11

1 reference

based on heuristic

inferred from title

15

1 reference

Europe PubMed Central

14 August 2017

Matthias Blüher

14

object named as

Matthias Blüher

1 reference

Europe PubMed Central

14 August 2017

Stefan R. Bornstein

11

object named as

Stefan R Bornstein

1 reference

Europe PubMed Central

14 August 2017

Graeme Eisenhofer

12

object named as

Graeme Eisenhofer

1 reference

Europe PubMed Central

14 August 2017

Triantafyllos Chavakis

19

object named as

Triantafyllos Chavakis

1 reference

Europe PubMed Central

14 August 2017

author name string

Rubén García-Martín

1

1 reference

Europe PubMed Central

14 August 2017

Vasileia I Alexaki

2

1 reference

Europe PubMed Central

14 August 2017

Nan Qin

3

1 reference

Europe PubMed Central

14 August 2017

María F Rubín de Celis

4

1 reference

Europe PubMed Central

14 August 2017

Matina Economopoulou

5

1 reference

Europe PubMed Central

14 August 2017

Athanasios Ziogas

6

1 reference

Europe PubMed Central

14 August 2017

Bettina Gercken

7

1 reference

Europe PubMed Central

14 August 2017

Klara Kotlabova

8

1 reference

Europe PubMed Central

14 August 2017

Julia Phieler

9

1 reference

Europe PubMed Central

14 August 2017

Monika Ehrhart-Bornstein

10

1 reference

Europe PubMed Central

14 August 2017

Georg Breier

13

1 reference

Europe PubMed Central

14 August 2017

Ali El-Armouche

16

1 reference

Europe PubMed Central

14 August 2017

Antonios Chatzigeorgiou

17

1 reference

Europe PubMed Central

14 August 2017

Kyoung-Jin Chung

18

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Europe PubMed Central

14 August 2017

language of work or name

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publication date

16 November 2015

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Europe PubMed Central

14 August 2017

Molecular and Cellular Biology

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Europe PubMed Central

14 August 2017

36

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Europe PubMed Central

14 August 2017

376-393

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Europe PubMed Central

14 August 2017

3

1 reference

Europe PubMed Central

14 August 2017

copyright license

Creative Commons Attribution 4.0 International

1 February 2016

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April 2023 Public Data File from Crossref

copyright status

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describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4719429/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Brown adipose tissue derived VEGF-A modulates cold tolerance and energy expenditure

1 reference

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30 September 2017

Increased adipocyte O2 consumption triggers HIF-1α, causing inflammation and insulin resistance in obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719429

30 September 2017

Vascular rarefaction mediates whitening of brown fat in obesity.

1 reference

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30 September 2017

Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance

1 reference

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30 September 2017

Brown and beige fat: development, function and therapeutic potential

1 reference

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30 September 2017

The complement anaphylatoxin C5a receptor contributes to obese adipose tissue inflammation and insulin resistance

1 reference

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30 September 2017

A liver Hif-2α-Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719429

30 September 2017

Cross-talk between hypoxia and insulin signaling through Phd3 regulates hepatic glucose and lipid metabolism and ameliorates diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719429

30 September 2017

Vascular endothelial growth factor is important for brown adipose tissue development and maintenance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719429

30 September 2017

Lessons on conditional gene targeting in mouse adipose tissue

1 reference

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30 September 2017

Lymphocytes in obesity-related adipose tissue inflammation

1 reference

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30 September 2017

Dichotomous effects of VEGF-A on adipose tissue dysfunction.

1 reference

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30 September 2017

Endothelial HIF-2α regulates murine pathological angiogenesis and revascularization processes

1 reference

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30 September 2017

The cellular and signaling networks linking the immune system and metabolism in disease

1 reference

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30 September 2017

The differential role of Hif1β/Arnt and the hypoxic response in adipose function, fibrosis, and inflammation

1 reference

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30 September 2017

Clodronate liposomes improve metabolic profile and reduce visceral adipose macrophage content in diet-induced obese mice

1 reference

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30 September 2017

Disruption of hypoxia-inducible factor 1 in adipocytes improves insulin sensitivity and decreases adiposity in high-fat diet-fed mice

1 reference

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30 September 2017

Increased adipose tissue oxygen tension in obese compared with lean men is accompanied by insulin resistance, impaired adipose tissue capillarization, and inflammation

1 reference

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A novel function of junctional adhesion molecule-C in mediating melanoma cell metastasis.

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30 September 2017

Hypoxia-inducible factors and the response to hypoxic stress

1 reference

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30 September 2017

Hypoxia-inducible factor 2alpha regulates macrophage function in mouse models of acute and tumor inflammation

1 reference

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30 September 2017

Adipose tissue angiogenesis as a therapeutic target for obesity and metabolic diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719429

30 September 2017

Uncoupling of inflammation and insulin resistance by NF-kappaB in transgenic mice through elevated energy expenditure

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30 September 2017

Inflammation and adipose tissue macrophages in lipodystrophic mice

1 reference

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30 September 2017

Hypoxia-inducible factor 2 regulates hepatic lipid metabolism

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Quantification of adiposity in small rodents using micro-CT

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30 September 2017

Metabolic dysregulation and adipose tissue fibrosis: role of collagen VI.

1 reference

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30 September 2017

Reduced adipose tissue oxygenation in human obesity: evidence for rarefaction, macrophage chemotaxis, and inflammation without an angiogenic response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719429

30 September 2017

Hypoxia-inducible factor-2 regulates vascular tumorigenesis in mice

1 reference

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30 September 2017

Regulation of LFA-1-dependent inflammatory cell recruitment by Cbl-b and 14-3-3 proteins

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30 September 2017

Obesity in C57BL/6J mice is characterized by adipose tissue hypoxia and cytotoxic T-cell infiltration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719429

30 September 2017

Hypoxia is a potential risk factor for chronic inflammation and adiponectin reduction in adipose tissue of ob/ob and dietary obese mice

1 reference

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30 September 2017

Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase

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Design and validation of a histological scoring system for nonalcoholic fatty liver disease

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30 September 2017

Brown adipose tissue: function and physiological significance

1 reference

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30 September 2017

Adipose-specific peroxisome proliferator-activated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle

1 reference

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Norepinephrine induces vascular endothelial growth factor gene expression in brown adipocytes through a beta -adrenoreceptor/cAMP/protein kinase A pathway involving Src but independently of Erk1/2

1 reference

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Adipose tissue overexpression of vascular endothelial growth factor protects against diet-induced obesity and insulin resistance.

1 reference

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28 June 2018

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28 June 2018

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28 June 2018

Adrenergic activation of vascular endothelial growth factor mRNA expression in rat brown adipose tissue: implication in cold-induced angiogenesis

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Adipose vascular endothelial growth factor regulates metabolic homeostasis through angiogenesis

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21 September 2018

Hypoxia-inducible factor 1alpha induces fibrosis and insulin resistance in white adipose tissue.

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21 September 2018

Norepinephrine but not hypoxia stimulates HIF-1alpha gene expression in brown adipocytes

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12 December 2020

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1 reference

https://pubmed.ncbi.nlm.nih.gov/26572826

12 December 2020

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https://pubmed.ncbi.nlm.nih.gov/26572826

12 December 2020

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Identifiers

10.1128/MCB.00430-15

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

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