(Q36486837)

14 August 2017

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title

The dark side of activation-induced cytidine deaminase: relationship with leukemia and beyond (English)

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14 August 2017

Kazuo Kinoshita

1

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14 August 2017

Taichiro Nonaka

series ordinal

2

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14 August 2017

publication date

1 April 2006

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International Journal of Hematology

14 August 2017

published in

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14 August 2017

volume

83

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14 August 2017

issue

3

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14 August 2017

page(s)

201-207

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DNA cleavage in immunoglobulin somatic hypermutation depends on de novo protein synthesis but not on uracil DNA glycosylase

14 August 2017

cites work

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12 December 2020

Immunoglobulin gene diversification

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12 December 2020

Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming

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12 December 2020

Chronic lymphocytic leukemia B cells expressing AID display dissociation between class switch recombination and somatic hypermutation

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12 December 2020

Linking class-switch recombination with somatic hypermutation

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12 December 2020

Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice

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12 December 2020

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

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12 December 2020

Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination

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12 December 2020

Somatic hypermutation of the AID transgene in B and non-B cells

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12 December 2020

Uracil DNA glycosylase activity is dispensable for immunoglobulin class switch

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12 December 2020

Mimicry of CD40 signals by Epstein-Barr virus LMP1 in B lymphocyte responses

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12 December 2020

Mutator dynamics in fluctuating environments.

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12 December 2020

CD38 expression and immunoglobulin variable region mutations are independent prognostic variables in chronic lymphocytic leukemia, but CD38 expression may vary during the course of the disease.

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12 December 2020

De novo protein synthesis is required for the activation-induced cytidine deaminase function in class-switch recombination

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12 December 2020

Prevalence of hepatitis C virus infection in patients with lymphoproliferative disorders

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12 December 2020

The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA

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12 December 2020

Activation and targeting of immunoglobulin switch recombination by activities induced by EBV infection

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12 December 2020

Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells

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12 December 2020

Cloning and expression of the AID gene in the channel catfish

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12 December 2020

Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase.

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12 December 2020

A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression

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12 December 2020

Somatic hypermutation of immunoglobulin genes

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12 December 2020

AID mutant analyses indicate requirement for class-switch-specific cofactors

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12 December 2020

Hepatitis C virus induces a mutator phenotype: enhanced mutations of immunoglobulin and protooncogenes

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12 December 2020

Inflammation and cancer

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12 December 2020

Separate domains of AID are required for somatic hypermutation and class-switch recombination

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12 December 2020

PKA-mediated phosphorylation regulates the function of activation-induced deaminase (AID) in B cells

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12 December 2020

Description of an in situ hybridization methodology for detection of Epstein-Barr virus RNA in paraffin-embedded tissues, with a survey of normal and neoplastic tissues

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12 December 2020

In Vitro Deamination of Cytosine to Uracil in Single-stranded DNA by Apolipoprotein B Editing Complex Catalytic Subunit 1 (APOBEC1)

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12 December 2020

Constitutive expression of AID leads to tumorigenesis

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12 December 2020

Epstein-Barr virus and cancer

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12 December 2020

V(H) mutation status, CD38 expression level, genomic aberrations, and survival in chronic lymphocytic leukemia.

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12 December 2020

Binding of hepatitis C virus to CD81

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12 December 2020

Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes

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12 December 2020

AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts

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12 December 2020

AID is expressed in germinal center B-cell-like and activated B-cell-like diffuse large-cell lymphomas and is not correlated with intraclonal heterogeneity.

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12 December 2020

EBV-Encoded Latent Membrane Protein 1 Cooperates with BAFF/BLyS and APRIL to Induce T Cell-Independent Ig Heavy Chain Class Switching

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12 December 2020

Stable expression and somatic hypermutation of antibody V regions in B-cell developmental pathways

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12 December 2020

Isolation, tissue distribution, and chromosomal localization of the human activation-induced cytidine deaminase (AID) gene

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12 December 2020

High expression of activation-induced cytidine deaminase (AID) mRNA is associated with unmutated IGVH gene status and unfavourable cytogenetic aberrations in patients with chronic lymphocytic leukaemia

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12 December 2020

Requirement of the activation-induced deaminase (AID) gene for immunoglobulin gene conversion

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12 December 2020

Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1

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12 December 2020

Replication protein A interacts with AID to promote deamination of somatic hypermutation targets

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12 December 2020

The AID antibody diversification enzyme is regulated by protein kinase A phosphorylation

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12 December 2020

Somatic hypermutation is limited by CRM1-dependent nuclear export of activation-induced deaminase

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12 December 2020

Stress-induced mutagenesis in bacteria

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12 December 2020

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

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12 December 2020

Activation-induced cytidine deaminase in chronic lymphocytic leukemia B cells: expression as multiple forms in a dynamic, variably sized fraction of the clone.

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12 December 2020

High expression of activation-induced cytidine deaminase (AID) and splice variants is a distinctive feature of poor-prognosis chronic lymphocytic leukemia

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12 December 2020

Hypermutation of HIV-1 DNA in the Absence of the Vif Protein

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12 December 2020

Class-switch recombination: interplay of transcription, DNA deamination and DNA repair

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12 December 2020

Organization of immunoglobulin heavy chain genes and allelic deletion model

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12 December 2020

DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL

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12 December 2020

Activation-induced deaminase: controversies and open questions

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12 December 2020

AID is required for c-myc/IgH chromosome translocations in vivo

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12 December 2020

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

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12 December 2020

Molecular cloning of canine activation-induced cytidine deaminase (AID) cDNA and its expression in normal tissues

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12 December 2020

C-terminal deletion of AID uncouples class switch recombination from somatic hypermutation and gene conversion.

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12 December 2020

RNA-editing cytidine deaminase Apobec-1 is unable to induce somatic hypermutation in mammalian cells

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12 December 2020

Molecular mechanism of class switch recombination: linkage with somatic hypermutation

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12 December 2020

Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein

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12 December 2020

Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand

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12 December 2020

Evolution of isotype switching

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12 December 2020

Bcl-2 rearrangement in patients with chronic hepatitis C associated with essential mixed cryoglobulinemia type II

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12 December 2020

De novo protein synthesis is required for activation-induced cytidine deaminase-dependent DNA cleavage in immunoglobulin class switch recombination

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12 December 2020

BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci

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12 December 2020

Multivariate analysis of prognostic factors in CLL: clinical stage, IGVH gene mutational status, and loss or mutation of the p53 gene are independent prognostic factors

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12 December 2020

Identifiers

DOI

10.1532/IJH97.06011

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Dimensions Publication ID

14 August 2017

1028230392

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