(Q36490763)

14 August 2017

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title

Unraveling the complex relationship between cancer immunity and autoimmunity: lessons from melanoma and vitiligo (English)

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14 August 2017

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7

Jedd D Wolchok

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14 August 2017

Hiroshi Uchi

1

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14 August 2017

Rodica Stan

2

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14 August 2017

Mary Jo Turk

3

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14 August 2017

Manuel E Engelhorn

4

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14 August 2017

Gabrielle A Rizzuto

5

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14 August 2017

Stacie M Goldberg

6

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14 August 2017

Alan N Houghton

8

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14 August 2017

publication date

1 January 2006

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14 August 2017

published in

Advances in Immunology

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14 August 2017

volume

90

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14 August 2017

page(s)

215-241

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Dendritic cell maturation is required for the cross-tolerization of CD8+ T cells

14 August 2017

cites work

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7 January 2021

High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993

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7 January 2021

Dendritic cells and the control of immunity

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7 January 2021

Accumulation of identical T cells in melanoma and vitiligo-like leukoderma

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7 January 2021

The CD8alpha(+) dendritic cell is responsible for inducing peripheral self-tolerance to tissue-associated antigens

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7 January 2021

Coupling and uncoupling of tumor immunity and autoimmunity

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7 January 2021

Targeted expression of major histocompatibility complex (MHC) class II molecules demonstrates that dendritic cells can induce negative but not positive selection of thymocytes in vivo

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7 January 2021

Manipulation of avidity to improve effectiveness of adoptively transferred CD8(+) T cells for melanoma immunotherapy in human MHC class I-transgenic mice

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7 January 2021

Prognostic significance of hypopigmentation in malignant melanoma

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7 January 2021

Generation of anergic and regulatory T cells following prolonged exposure to a harmless antigen

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7 January 2021

CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunity

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7 January 2021

DNA-PKcs is required for activation of innate immunity by immunostimulatory DNA.

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7 January 2021

Fc receptors are required in passive and active immunity to melanoma

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7 January 2021

Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets

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7 January 2021

Plasmacytoid dendritic cells in immunity

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7 January 2021

A symbiotic concept of autoimmunity and tumour immunity: lessons from vitiligo

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7 January 2021

Peripheral deletion of autoreactive CD8 T cells by cross presentation of self-antigen occurs by a Bcl-2-inhibitable pathway mediated by Bim

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7 January 2021

Boosting T cell-mediated immunity to tyrosinase by vaccinia virus-transduced, CD34(+)-derived dendritic cell vaccination: a phase I trial in metastatic melanoma

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7 January 2021

Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity

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7 January 2021

Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes

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7 January 2021

Prolonged survival in metastatic malignant melanoma associated with vitiligo

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7 January 2021

Heteroclitic immunization induces tumor immunity

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7 January 2021

Antigen persistence and time of T-cell tolerization determine the efficacy of tolerization protocols for prevention of skin graft rejection

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7 January 2021

Dendritic cells in cancer immunotherapy

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7 January 2021

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

In Vivo Destruction of Melanocytes by the IgG Fraction of Serum from Patients with Vitiligo

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Generation of human CD8 T regulatory cells by CD40 ligand-activated plasmacytoid dendritic cells

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Comparison of two cancer vaccines targeting tyrosinase: plasmid DNA and recombinant alphavirus replicon particles

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Depletion of CD25+ regulatory cells uncovers immune responses to shared murine tumor rejection antigens

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7 January 2021

CTLA-4 blockade in combination with xenogeneic DNA vaccines enhances T-cell responses, tumor immunity and autoimmunity to self antigens in animal and cellular model systems

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Topical tacrolimus for repigmentation of vitiligo

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Role of dendritic cells in the generation of regulatory T cells

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7 January 2021

Implicating a role for immune recognition of self in tumor rejection: passive immunization against the brown locus protein

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7 January 2021

Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Immunization with DNA coding for gp100 results in CD4 T-cell independent antitumor immunity

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

A Toll-like receptor recognizes bacterial DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

A critique of the evidence for active host defence against cancer, based on personal studies of 27 murine tumours of spontaneous origin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Control of regulatory T cell development by the transcription factor Foxp3

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7 January 2021

Immunity against cancer: lessons learned from melanoma.

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7 January 2021

Mouse monoclonal IgG3 antibody detecting GD3 ganglioside: a phase I trial in patients with malignant melanoma

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7 January 2021

Transgenic mouse model for skin malignant melanoma

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7 January 2021

Autoantibodies to human melanocyte-specific protein pmel17 in the sera of vitiligo patients: a sensitive and quantitative radioimmunoassay (RIA)

1 reference

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7 January 2021

Autoantibodies to tyrosinase-related protein-1 detected in the sera of vitiligo patients using a quantitative radiobinding assay

1 reference

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7 January 2021

The melanin-concentrating hormone receptor 1, a novel target of autoantibody responses in vitiligo

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7 January 2021

CpG DNA augments the immunogenicity of plasmid DNA vaccines

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7 January 2021

CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma

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7 January 2021

Murine cutaneous mastocytosis and epidermal melanocytosis induced by keratinocyte expression of transgenic stem cell factor

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7 January 2021

Vaccination-induced autoimmune vitiligo is a consequence of secondary trauma to the skin

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

HLA-A2 Restricted, Melanocyte-Specific CD8+ T Lymphocytes Detected in Vitiligo Patients are Related to Disease Activity and are Predominantly Directed Against MelanA/MART1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Direct evidence to support the role of antigen-specific CD8(+) T cells in melanoma-associated vitiligo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Spontaneous vitiligo in an animal model for human melanoma: role of tumor-specific CD8+ T cells.

1 reference

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7 January 2021

Phase I study in melanoma patients of a vaccine with peptide-pulsed dendritic cells generated in vitro from CD34(+) hematopoietic progenitor cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Tolerance and cancer: mechanisms of tumor evasion and strategies for breaking tolerance

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7 January 2021

Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: half of patients respond to a four-dose treatment program.

1 reference

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7 January 2021

GITR activation induces an opposite effect on alloreactive CD4(+) and CD8(+) T cells in graft-versus-host disease

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Immune response to a differentiation antigen induced by altered antigen: a study of tumor rejection and autoimmunity

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7 January 2021

Elimination of CD4(+) T cells enhances anti-tumor effect of locally secreted interleukin-12 on B16 mouse melanoma and induces vitiligo-like coat color alteration

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

In vivo elimination of CD25+ regulatory T cells leads to tumor rejection of B16F10 melanoma, when combined with interleukin-12 gene transfer

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Dendritic cell vaccination for cancer therapy

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Role of self-peptides in positively selecting the T-cell repertoire

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Dominant role of the niche in melanocyte stem-cell fate determination

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

A new member of the tumor necrosis factor/nerve growth factor receptor family inhibits T cell receptor-induced apoptosis

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7 January 2021

Vitiligo in patients with metastatic melanoma: a good prognostic sign

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7 January 2021

High frequency of skin-homing melanocyte-specific cytotoxic T lymphocytes in autoimmune vitiligo

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7 January 2021

Vaccination with a recombinant vaccinia virus encoding a "self" antigen induces autoimmune vitiligo and tumor cell destruction in mice: requirement for CD4(+) T lymphocytes.

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7 January 2021

Tumor regression and autoimmunity after reversal of a functionally tolerant state of self-reactive CD8+ T cells.

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7 January 2021

Specific cytotoxic T lymphocyte responses against Melan-A/MART1, tyrosinase and gp100 in vitiligo by the use of major histocompatibility complex/peptide tetramers: the role of cellular immunity in the etiopathogenesis of vitiligo.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Factors associated with response to high-dose interleukin-2 in patients with metastatic melanoma

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Divergent roles for Fc receptors and complement in vivo

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Adjuvant immunotherapy with tumor infiltrating lymphocytes and interleukin-2 in patients with resected stage III and IV melanoma

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7 January 2021

Cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma: a new cause of uveitis

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7 January 2021

Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma

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7 January 2021

CpG-matured murine plasmacytoid dendritic cells are capable of in vivo priming of functional CD8 T cell responses to endogenous but not exogenous antigens

1 reference

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7 January 2021

Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation

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7 January 2021

Autoimmunity in a phase I trial of a fully human anti-cytotoxic T-lymphocyte antigen-4 monoclonal antibody with multiple melanoma peptides and Montanide ISA 51 for patients with resected stages III and IV melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Immunostimulatory DNA sequences necessary for effective intradermal gene immunization

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

CpG motifs are efficient adjuvants for DNA cancer vaccines

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Overlap between molecular markers expressed by naturally occurring CD4+CD25+ regulatory T cells and antigen specific CD4+CD25+ and CD8+CD28- T suppressor cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance

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7 January 2021

Clinical response after intradermal immature dendritic cell vaccination in metastatic melanoma is associated with immune response to particulate antigen.

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7 January 2021

The role of tyrosinase in autoimmune vitiligo

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Bacterial CpG-DNA activates dendritic cells in vivo: T helper cell-independent cytotoxic T cell responses to soluble proteins

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Tolerogenic dendritic cells

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Avoiding horror autotoxicus: the importance of dendritic cells in peripheral T cell tolerance

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

The induction of tolerance by dendritic cells that have captured apoptotic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Genetic immunization with a melanocytic self-antigen linked to foreign helper sequences breaks tolerance and induces autoimmunity and tumor immunity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Immune response to green fluorescent protein: implications for gene therapy

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Type I interferon-mediated stimulation of T cells by CpG DNA

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Redundant and alternative roles for activating Fc receptors and complement in an antibody-dependent model of autoimmune vitiligo

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Phase I trial of a mouse monoclonal antibody against GD3 ganglioside in patients with melanoma: induction of inflammatory responses at tumor sites

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accomp

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Elucidating the autoimmune and antitumor effector mechanisms of a treatment based on cytotoxic T lymphocyte antigen-4 blockade in combination with a B16 melanoma vaccine: comparison of prophylaxis and therapy

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

The melanoma antigen gp75 is the human homologue of the mouse b (brown) locus gene product

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Tumor immunity and autoimmunity induced by immunization with homologous DNA

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https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Immunostimulatory oligodeoxynucleotides containing the CpG motif are effective as immune adjuvants in tumor antigen immunization

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

Melanocyte destruction after antigen-specific immunotherapy of melanoma: direct evidence of t cell-mediated vitiligo.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2806%2990006-6

7 January 2021

10.1016/S0065-2776(06)90006-6

Identifiers

DOI

1 reference

14 August 2017

1 reference