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FOXO-regulated transcription restricts overgrowth of Tsc mutant organs
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
2265581
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299344%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
title
FOXO-regulated transcription restricts overgrowth of Tsc mutant organs
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2265581
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299344%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
author
Kieran Harvey
series ordinal
1
1 reference
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Europe PubMed Central
PMC publication ID
2265581
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299344%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
Frederick C Bennett
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4
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Europe PubMed Central
PMC publication ID
2265581
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299344%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
Matthew R. Ramsey
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5
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Europe PubMed Central
PMC publication ID
2265581
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299344%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
Oscar Puig
series ordinal
7
1 reference
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Europe PubMed Central
PMC publication ID
2265581
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299344%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
Leif W Ellisen
series ordinal
6
object named as
Leif W Ellisen
1 reference
stated in
Europe PubMed Central
PMC publication ID
2265581
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299344%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
author name string
Jaakko Mattila
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
2265581
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299344%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
Avi Sofer
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
2265581
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299344%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
Iswar K Hariharan
series ordinal
8
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Europe PubMed Central
PMC publication ID
2265581
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299344%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
language of work or name
English
0 references
publication date
1 February 2008
1 reference
stated in
Europe PubMed Central
PMC publication ID
2265581
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299344%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
number of pages
6
1 reference
based on heuristic
inferred from page(s)
published in
Journal of Cell Biology
1 reference
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Europe PubMed Central
PMC publication ID
2265581
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299344%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
volume
180
1 reference
stated in
Europe PubMed Central
PMC publication ID
2265581
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299344%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
issue
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
2265581
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299344%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
page(s)
691-696
1 reference
stated in
Europe PubMed Central
PMC publication ID
2265581
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299344%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
cites work
FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265581
retrieved
30 September 2017
TOR signaling in growth and metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265581
retrieved
30 September 2017
FOXO transcription factors at the interface between longevity and tumor suppression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265581
retrieved
30 September 2017
The insulin-PI3K/TOR pathway induces a HIF-dependent transcriptional response in Drosophila by promoting nuclear localization of HIF-alpha/Sima
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265581
retrieved
30 September 2017
Feedback inhibition of Akt signaling limits the growth of tumors lacking Tsc2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265581
retrieved
30 September 2017
Genetic analysis of Pten and Tsc2 functional interactions in the mouse reveals asymmetrical haploinsufficiency in tumor suppression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265581
retrieved
30 September 2017
Regulation of mTOR and cell growth in response to energy stress by REDD1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265581
retrieved
30 September 2017
The plasticity of aging: insights from long-lived mutants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265581
retrieved
30 September 2017
Dysregulation of the TSC-mTOR pathway in human disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265581
retrieved
30 September 2017
The hypoxia-induced paralogs Scylla and Charybdis inhibit growth by down-regulating S6K activity upstream of TSC in Drosophila
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265581
retrieved
30 September 2017
Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265581
retrieved
30 September 2017
Balancing Akt with S6K: implications for both metabolic diseases and tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265581
retrieved
30 September 2017
Targeting the PI3K-Akt pathway in human cancer: rationale and promise
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265581
retrieved
30 September 2017
Loss of Tsc1/Tsc2 activates mTOR and disrupts PI3K-Akt signaling through downregulation of PDGFR
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265581
retrieved
30 September 2017
The Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265581
retrieved
30 September 2017
Drosophila Rheb GTPase is required for cell cycle progression and cell growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265581
retrieved
30 September 2017
Control of cell number by Drosophila FOXO: downstream and feedback regulation of the insulin receptor pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265581
retrieved
30 September 2017
Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265581
retrieved
30 September 2017
REDD1, a developmentally regulated transcriptional target of p63 and p53, links p63 to regulation of reactive oxygen species
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265581
retrieved
30 September 2017
Lethality of Drosophila lacking TSC tumor suppressor function rescued by reducing dS6K signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265581
retrieved
30 September 2017
Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265581
retrieved
30 September 2017
TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265581
retrieved
30 September 2017
Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265581
retrieved
30 September 2017
The spineless-aristapedia and tango bHLH-PAS proteins interact to control antennal and tarsal development in Drosophila
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265581
retrieved
30 September 2017
High-resolution dynamics of the transcriptional response to nutrition in Drosophila: a key role for dFOXO.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265581
retrieved
21 September 2018
Fat cadherin modulates organ size in Drosophila via the Salvador/Warts/Hippo signaling pathway.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265581
retrieved
21 September 2018
The translational inhibitor 4E-BP is an effector of PI(3)K/Akt signalling and cell growth in Drosophila
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265581
retrieved
21 September 2018
Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265581
retrieved
21 September 2018
The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265581
retrieved
21 September 2018
Identifiers
DOI
10.1083/JCB.200710100
1 reference
stated in
Europe PubMed Central
PMC publication ID
2265581
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299344%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
PMC publication ID
2265581
1 reference
stated in
Europe PubMed Central
PMC publication ID
2265581
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299344%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
PubMed publication ID
18299344
1 reference
stated in
Europe PubMed Central
PMC publication ID
2265581
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18299344%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 January 2020
ResearchGate publication ID
5553642
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