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BCL2 family in DNA damage and cell cycle control
scientific article published on 9 June 2006
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scholarly article
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Europe PubMed Central
PubMed ID
16763616
retrieved
14 August 2017
review article
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Europe PubMed Central
title
BCL2 family in DNA damage and cell cycle control
(English)
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Europe PubMed Central
PubMed ID
16763616
retrieved
14 August 2017
main subject
DNA damage
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author
Sandra S. Zinkel
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1
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Zinkel S
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Europe PubMed Central
PubMed ID
16763616
retrieved
14 August 2017
author name string
Gross A
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2
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Europe PubMed Central
PubMed ID
16763616
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14 August 2017
Yang E
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3
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Europe PubMed Central
PubMed ID
16763616
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14 August 2017
publication date
9 June 2006
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Europe PubMed Central
PubMed ID
16763616
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14 August 2017
published in
Cell Death & Differentiation
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Europe PubMed Central
PubMed ID
16763616
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14 August 2017
volume
13
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Europe PubMed Central
PubMed ID
16763616
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14 August 2017
page(s)
1351-1359
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Europe PubMed Central
PubMed ID
16763616
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14 August 2017
issue
8
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Europe PubMed Central
PubMed ID
16763616
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14 August 2017
exact match
https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401987
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Cells en route to apoptosis are characterized by the upregulation of c-fos, c-myc, c-jun, cdc2, and RB phosphorylation, resembling events of early cell-cycle traverse.
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Activation of cyclin A-dependent protein kinases during apoptosis
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7 January 2021
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Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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7 January 2021
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The cell death inhibitor Bcl-2 and its homologues influence control of cell cycle entry
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bcl-2 transgene expression promotes survival and reduces proliferation of CD3-CD4-CD8- T cell progenitors
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The anti-apoptosis function of Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry
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Cross talk between cell death and cell cycle progression: BCL-2 regulates NFAT-mediated activation.
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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7 January 2021
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Regulation of cell division cycle progression by bcl-2 expression: a potential mechanism for inhibition of programmed cell death
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7 January 2021
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Diminished cell proliferation associated with the death-protective activity of Bcl-2
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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Bcl-2 over-expression reduces growth rate and prolongs G1 phase in continuous chemostat cultures of hybridoma cells
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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7 January 2021
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Bax alpha perturbs T cell development and affects cell cycle entry of T cells
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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7 January 2021
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Bcl-2 retards cell cycle entry through p27(Kip1), pRB relative p130, and altered E2F regulation
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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7 January 2021
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BCL-x(L) and BCL2 delay Myc-induced cell cycle entry through elevation of p27 and inhibition of G1 cyclin-dependent kinases
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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7 January 2021
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Bcl-xL/Bcl-2 coordinately regulates apoptosis, cell cycle arrest and cell cycle entry
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Bcl-2 inhibition of T-cell proliferation is related to prolonged T-cell survival.
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7 January 2021
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Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14;18)
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Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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Cooperative interaction between c-myc and bcl-2 proto-oncogenes
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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7 January 2021
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Apoptotic cell death induced by c-myc is inhibited by bcl-2.
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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Three distinct IL-2 signaling pathways mediated by bcl-2, c-myc, and lck cooperate in hematopoietic cell proliferation
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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Evaluation of multiple bio-pathological factors in colorectal adenocarcinomas: independent prognostic role of p53 and bcl-2.
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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7 January 2021
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Bcl-2 expression inhibits liver carcinogenesis and delays the development of proliferating foci
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7 January 2021
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Bcl-2 expression delays hepatocyte cell cycle progression during liver regeneration
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7 January 2021
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Loss of anti-mitotic effects of Bcl-2 with retention of anti-apoptotic activity during tumor progression in a mouse model
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7 January 2021
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Bcl-2 expression delays mammary tumor development in dimethylbenz(a)anthracene-treated transgenic mice.
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Overexpression of Bcl-W in the testis disrupts spermatogenesis: revelation of a role of BCL-W in male germ cell cycle control
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Apoptosis regulator bcl-w is essential for spermatogenesis but appears otherwise redundant
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2
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Regulation of apoptosis and cell cycle progression by MCL1. Differential role of proliferating cell nuclear antigen
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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A proteolytic fragment of Mcl-1 exhibits nuclear localization and regulates cell growth by interaction with Cdk1.
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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A1 is a growth-permissive antiapoptotic factor mediating postactivation survival in T cells
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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A link between cell cycle and cell death: Bax and Bcl-2 modulate Cdk2 activation during thymocyte apoptosis.
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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Deficiency in Bak and Bax perturbs thymic selection and lymphoid homeostasis.
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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Bax suppresses tumorigenesis and stimulates apoptosis in vivo
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bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis
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BAX and BAK mediate p53-independent suppression of tumorigenesis
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BAD/BCL-[X(L)] heterodimerization leads to bypass of G0/G1 arrest
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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7 January 2021
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Bad-deficient mice develop diffuse large B cell lymphoma
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BID: a novel BH3 domain-only death agonist
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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7 January 2021
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Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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7 January 2021
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Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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7 January 2021
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Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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7 January 2021
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Proapoptotic BID is required for myeloid homeostasis and tumor suppression
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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7 January 2021
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Deletion of Bid impedes cell proliferation and hepatic carcinogenesis
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Cell death: critical control points
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7 January 2021
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Cytochrome c release upon Fas receptor activation depends on translocation of full-length bid and the induction of the mitochondrial permeability transition
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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7 January 2021
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Translocation of full-length Bid to mitochondria during anoikis
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7 January 2021
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PACS-2 controls endoplasmic reticulum-mitochondria communication and Bid-mediated apoptosis
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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7 January 2021
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BID-D59A is a potent inducer of apoptosis in primary embryonic fibroblasts
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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7 January 2021
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Phosphorylation of bid by casein kinases I and II regulates its cleavage by caspase 8.
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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7 January 2021
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A role for proapoptotic BID in the DNA-damage response
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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7 January 2021
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Proapoptotic BID is an ATM effector in the DNA-damage response
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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7 January 2021
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Mice defective in two apoptosis pathways in the myeloid lineage develop acute myeloblastic leukemia
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7 January 2021
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p63 and p73 are required for p53-dependent apoptosis in response to DNA damage
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ASPP proteins specifically stimulate the apoptotic function of p53
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7 January 2021
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Integral role of Noxa in p53-mediated apoptotic response
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7 January 2021
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Puma is an essential mediator of p53-dependent and -independent apoptotic pathways
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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7 January 2021
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p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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7 January 2021
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Wild-type p53 transactivates the KILLER/DR5 gene through an intronic sequence-specific DNA-binding site.
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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A model for p53-induced apoptosis
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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7 January 2021
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Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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7 January 2021
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Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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7 January 2021
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PUMA couples the nuclear and cytoplasmic proapoptotic function of p53
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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7 January 2021
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Involvement of histone H1.2 in apoptosis induced by DNA double-strand breaks
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7 January 2021
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BID regulation by p53 contributes to chemosensitivity
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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7 January 2021
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The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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7 January 2021
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Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function
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reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401987
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7 January 2021
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Identifiers
DOI
10.1038/SJ.CDD.4401987
1 reference
stated in
Europe PubMed Central
PubMed ID
16763616
retrieved
14 August 2017
Dimensions Publication ID
1039131101
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PubMed ID
16763616
1 reference
stated in
Europe PubMed Central
PubMed ID
16763616
retrieved
14 August 2017
ResearchGate publication ID
7018951
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