(Q36505689)

English

Appl1 and Appl2 are Expendable for Mouse Development But Are Essential for HGF-Induced Akt Activation and Migration in Mouse Embryonic Fibroblasts

scientific article published on 7 October 2015

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scholarly article

1 reference

Europe PubMed Central

14 August 2017

Appl1 and Appl2 are Expendable for Mouse Development But Are Essential for HGF-Induced Akt Activation and Migration in Mouse Embryonic Fibroblasts (English)

1 reference

Europe PubMed Central

14 August 2017

Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2

1 reference

GOA release 2020-03-11

Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1

1 reference

GOA release 2020-03-11

object named as

David L Wiest

4

0 references

author name string

Yinfei Tan

1

1 reference

Europe PubMed Central

14 August 2017

Xiaoban Xin

2

1 reference

Europe PubMed Central

14 August 2017

Francis J Coffey

3

1 reference

Europe PubMed Central

14 August 2017

Lily Q Dong

5

1 reference

Europe PubMed Central

14 August 2017

Joseph R Testa

6

1 reference

Europe PubMed Central

14 August 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

7 October 2015

1 reference

Europe PubMed Central

14 August 2017

Journal of Cellular Physiology

1 reference

Europe PubMed Central

14 August 2017

231

1 reference

Europe PubMed Central

14 August 2017

5

1 reference

Europe PubMed Central

14 August 2017

1142-1150

1 reference

Europe PubMed Central

14 August 2017

Rab31 and APPL2 enhance FcγR-mediated phagocytosis through PI3K/Akt signaling in macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728037

30 September 2017

APPL1 potentiates insulin sensitivity by facilitating the binding of IRS1/2 to the insulin receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728037

30 September 2017

APPL proteins modulate DNA repair and radiation survival of pancreatic carcinoma cells by regulating ATM.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728037

30 September 2017

Deficiency of APPL1 in mice impairs glucose-stimulated insulin secretion through inhibition of pancreatic beta cell mitochondrial function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728037

30 September 2017

APPL1 potentiates insulin secretion in pancreatic β cells by enhancing protein kinase Akt-dependent expression of SNARE proteins in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728037

30 September 2017

The endosomal adaptor protein APPL1 impairs the turnover of leading edge adhesions to regulate cell migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728037

30 September 2017

Adiponectin inhibits osteoclastogenesis and bone resorption via APPL1-mediated suppression of Akt1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728037

30 September 2017

Appl1 is dispensable for Akt signaling in vivo and mouse T-cell development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728037

30 September 2017

Appl1 is dispensable for mouse development, and loss of Appl1 has growth factor-selective effects on Akt signaling in murine embryonic fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728037

30 September 2017

Yin-Yang regulation of adiponectin signaling by APPL isoforms in muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728037

30 September 2017

Noncoding mutations of HGF are associated with nonsyndromic hearing loss, DFNB39.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728037

30 September 2017

Membrane targeting by APPL1 and APPL2: dynamic scaffolds that oligomerize and bind phosphoinositides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728037

30 September 2017

The interaction of Akt with APPL1 is required for insulin-stimulated Glut4 translocation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728037

30 September 2017

A role of the Lowe syndrome protein OCRL in early steps of the endocytic pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728037

30 September 2017

Structure of the APPL1 BAR-PH domain and characterization of its interaction with Rab5

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728037

30 September 2017

Crystal structures of the BAR-PH and PTB domains of human APPL1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728037

30 September 2017

APPL1 associates with TrkA and GIPC1 and is required for nerve growth factor-mediated signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728037

30 September 2017

Transcription factor Ets-1 regulates fibroblast growth factor-1-mediated angiogenesis in vivo: role of Ets-1 in the regulation of the PI3K/AKT/MMP-1 pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728037

30 September 2017

APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728037

30 September 2017

RNA interference reveals that ligand-independent met activity is required for tumor cell signaling and survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728037

30 September 2017

Human follicle-stimulating hormone (FSH) receptor interacts with the adaptor protein APPL1 in HEK 293 cells: potential involvement of the PI3K pathway in FSH signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728037

30 September 2017

Hepatocyte growth factor/c-met signaling pathway is required for efficient liver regeneration and repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728037

30 September 2017

APPL proteins link Rab5 to nuclear signal transduction via an endosomal compartment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728037

30 September 2017

The BAR-domain family of proteins: a case of bending and binding?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728037

30 September 2017

Identification of a chromosome 3p14.3-21.1 gene, APPL, encoding an adaptor molecule that interacts with the oncoprotein-serine/threonine kinase AKT2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728037

30 September 2017

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728037

30 September 2017

Recruitment of APPL1 to ubiquitin-rich aggresomes in response to proteasomal impairment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728037

28 June 2018

Akt2 mRNA is highly expressed in embryonic brown fat and the AKT2 kinase is activated by insulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728037

28 June 2018

Expression of a constitutively activated form of protein kinase B (c-Akt) in 3T3-L1 preadipose cells causes spontaneous differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728037

28 June 2018

Appl1 is essential for the survival of Xenopus pancreas, duodenum, and stomach progenitor cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728037

21 September 2018

The endosomal protein Appl1 mediates Akt substrate specificity and cell survival in vertebrate development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728037

21 September 2018

Loss of hepatocyte growth factor/c-Met signaling pathway accelerates early stages of N-nitrosodiethylamine induced hepatocarcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4728037

21 September 2018

Following the tracks of AKT1 gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/26445298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of glycogen synthesis by insulin requires S6 kinase and phosphatidylinositol-3-kinase in HTC-IR cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/26445298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/JCP.25211

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

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