(Q36510902)

14 August 2017

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title

The role of the transporter P-glycoprotein for disposition and effects of centrally acting drugs and for the pathogenesis of CNS diseases (English)

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14 August 2017

Norbert Thuerauf

1

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PubMed ID

16783494

14 August 2017

Martin Friedrich Fromm

series ordinal

2

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14 August 2017

1 August 2006

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European Archives of Psychiatry and Clinical Neuroscience

14 August 2017

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14 August 2017

256

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14 August 2017

5

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14 August 2017

281-286

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https://scigraph.springernature.com/pub.10.1007/s00406-006-0662-6

14 August 2017

0 references

cites work

Inhibition of P-glycoprotein-mediated drug transport: A unifying mechanism to explain the interaction between digoxin and quinidine [seecomments]

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00406-006-0662-6

Parkinson's disease and exposure to agricultural work and pesticide chemicals

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00406-006-0662-6

Modulation of the blood-brain barrier in oncology: therapeutic opportunities for the treatment of brain tumours?

21 January 2018

1 reference

12 December 2020

P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs

1 reference

12 December 2020

Anti-HIV drug distribution to the central nervous system

1 reference

12 December 2020

In vitro P-glycoprotein affinity for atypical and conventional antipsychotics

1 reference

12 December 2020

Expression polymorphism of the blood-brain barrier component P-glycoprotein (MDR1) in relation to Parkinson's disease.

1 reference

12 December 2020

P-glycoprotein expression and function in circulating blood cells from normal volunteers.

1 reference

12 December 2020

Penetration of endogenous steroid hormones corticosterone, cortisol, aldosterone and progesterone into the brain is enhanced in mice deficient for both mdr1a and mdr1b P-glycoproteins

1 reference

12 December 2020

ABC transporters and the blood-brain barrier

1 reference

12 December 2020

A common P-glycoprotein polymorphism is associated with nortriptyline-induced postural hypotension in patients treated for major depression

1 reference

12 December 2020

Polymorphism in the P-glycoprotein drug transporter MDR1 gene: a possible link between environmental and genetic factors in Parkinson's disease.

1 reference

12 December 2020

Role of intestinal P-glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine

1 reference

12 December 2020

Differential enhancement of antidepressant penetration into the brain in mice with abcb1ab (mdr1ab) P-Glycoprotein gene disruption

1 reference

12 December 2020

How significant is the role of P-glycoprotein in drug absorption and brain uptake?

1 reference

12 December 2020

Increased drug delivery to the brain by P-glycoprotein inhibition

1 reference

12 December 2020

Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy.

1 reference

12 December 2020

Polymorphisms in human MDR1 (P-glycoprotein): recent advances and clinical relevance

1 reference

12 December 2020

Do antidepressants regulate how cortisol affects the brain?

1 reference

12 December 2020

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

1 reference

12 December 2020

beta-Amyloid efflux mediated by p-glycoprotein

1 reference

12 December 2020

ABCB1 (MDR1)-type P-glycoproteins at the blood-brain barrier modulate the activity of the hypothalamic-pituitary-adrenocortical system: implications for affective disorder

1 reference

12 December 2020

Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites

1 reference

12 December 2020

St John's Wort induces intestinal P-glycoprotein/MDR1 and intestinal and hepatic CYP3A4

1 reference

12 December 2020

The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin

1 reference

12 December 2020

Deposition of Alzheimer's beta-amyloid is inversely correlated with P-glycoprotein expression in the brains of elderly non-demented humans.

1 reference

12 December 2020

Environmental risk factors in Parkinson's disease

1 reference

12 December 2020

Association of Multidrug Resistance in Epilepsy with a Polymorphism in the Drug-Transporter GeneABCB1

1 reference

12 December 2020

Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

1 reference

12 December 2020

Penetration of amitriptyline, but not of fluoxetine, into brain is enhanced in mice with blood-brain barrier deficiency due to mdr1a P-glycoprotein gene disruption

1 reference

12 December 2020

Genetic polymorphism in MDR-1: a tool for examining allelic expression in normal cells, unselected and drug-selected cell lines, and human tumors.

1 reference

12 December 2020

Limbic seizures induce P-glycoprotein in rodent brain: functional implications for pharmacoresistance.

1 reference

12 December 2020

Induction of P-glycoprotein by rifampin increases intestinal secretion of talinolol in human beings: a new type of drug/drug interaction

1 reference

12 December 2020

Herb-drug interactions

1 reference

12 December 2020

Functional expression and localization of P-glycoprotein in the central nervous system: relevance to the pathogenesis and treatment of neurological disorders

1 reference

12 December 2020

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

1 reference

12 December 2020

abcb1ab P-glycoprotein is involved in the uptake of citalopram and trimipramine into the brain of mice

1 reference

12 December 2020

The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors

1 reference

12 December 2020

Importance of P-glycoprotein at blood-tissue barriers

1 reference

12 December 2020

Genetic polymorphisms of the human MDR1 drug transporter

1 reference

12 December 2020

Indinavir concentrations and St John's wort.

1 reference

12 December 2020

10.1007/S00406-006-0662-6

Identifiers

DOI

1 reference

14 August 2017

1 reference

PubMed ID

16783494