(Q36511768)

English

Vaccinia virus lacking the deoxyuridine triphosphatase gene (F2L) replicates well in vitro and in vivo, but is hypersensitive to the antiviral drug (N)-methanocarbathymidine

scientific article published on 5 March 2008

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18321387%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Vaccinia virus lacking the deoxyuridine triphosphatase gene (F2L) replicates well in vitro and in vivo, but is hypersensitive to the antiviral drug (N)-methanocarbathymidine (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18321387%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

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Vaccinia virus

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1

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3 January 2020

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Earl R Kern

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3 January 2020

Debra C Quenelle

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3 January 2020

Kathy A Keith

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3 January 2020

Richard W Moyer

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3 January 2020

Peter C Turner

6

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3 January 2020

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5 March 2008

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3 January 2020

Virology Journal

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3 January 2020

5

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3 January 2020

39

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3 January 2020

Efficacy of N-methanocarbathymidine in treating mice infected intranasally with the IHD and WR strains of vaccinia virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276199

30 September 2017

Structures of vaccinia virus dUTPase and its nucleotide complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276199

30 September 2017

Selective phosphorylation of antiviral drugs by vaccinia virus thymidine kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276199

30 September 2017

The history of N-methanocarbathymidine: the investigation of a conformational concept leads to the discovery of a potent and selective nucleoside antiviral agent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276199

30 September 2017

Activity and mechanism of action of N-methanocarbathymidine against herpesvirus and orthopoxvirus infections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276199

30 September 2017

Uracils as a cellular weapon against viruses and mechanisms of viral escape.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276199

30 September 2017

Uracil in DNA--occurrence, consequences and repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276199

30 September 2017

Evolution of the DUT gene: horizontal transfer between host and pathogen in all three domains of life

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276199

30 September 2017

Roles of uracil-DNA glycosylase and dUTPase in virus replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276199

30 September 2017

Purification and properties of the deoxyuridine triphosphate nucleotidohydrolase enzyme derived from HeLa S3 cells. Comparison to a distinct dUTP nucleotidohydrolase induced in herpes simplex virus-infected HeLa S3 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276199

30 September 2017

Herpes simplex virus type 1 dUTPase mutants are attenuated for neurovirulence, neuroinvasiveness, and reactivation from latency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276199

30 September 2017

Purification and characterization of the vaccinia virus deoxyuridine triphosphatase expressed in Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276199

28 June 2018

Deletion of 55 open reading frames from the termini of vaccinia virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276199

28 June 2018

A PCR-based method for manipulation of the vaccinia virus genome that eliminates the need for cloning

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276199

28 June 2018

Vaccinia virus encodes a functional dUTPase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276199

21 September 2018

The white pock mutants of rabbit poxvirus I. Spontaneous host range mutants contian deletions

1 reference

https://pubmed.ncbi.nlm.nih.gov/18321387

12 December 2020

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10.1186/1743-422X-5-39

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Europe PubMed Central

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3 January 2020

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Europe PubMed Central

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3 January 2020

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Europe PubMed Central

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3 January 2020

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