(Q36521428)

14 August 2017

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title

Structure and function of the components of the human DNA mismatch repair system (English)

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14 August 2017

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Thomas Jascur

1

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14 August 2017

C Richard Boland

series ordinal

2

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14 August 2017

language of work or name

English

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publication date

1 November 2006

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International Journal of Cancer

14 August 2017

number of pages

6

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based on heuristic

inferred from page(s)

published in

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14 August 2017

volume

119

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14 August 2017

issue

9

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14 August 2017

page(s)

2030-2035

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The frequency of hereditary defective mismatch repair in a prospective series of unselected colorectal carcinomas

14 August 2017

cites work

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Use of microsatellite instability and immunohistochemistry testing for the identification of individuals at risk for Lynch syndrome

21 January 2018

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New developments in Lynch syndrome (hereditary nonpolyposis colorectal cancer) and mismatch repair gene testing

21 January 2018

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Mechanisms and biological effects of mismatch repair

21 January 2018

1 reference

Eukaryotic DNA mismatch repair

21 January 2018

1 reference

21 January 2018

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Mismatch repair and DNA damage signalling

21 January 2018

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The human mismatch recognition complex hMSH2-hMSH6 functions as a novel molecular switch

21 January 2018

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Nucleotide-promoted release of hMutSalpha from heteroduplex DNA is consistent with an ATP-dependent translocation mechanism

21 January 2018

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Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma

21 January 2018

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Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers.

21 January 2018

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Inactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility

21 January 2018

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Human exonuclease I is required for 5' and 3' mismatch repair

21 January 2018

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A defined human system that supports bidirectional mismatch-provoked excision

21 January 2018

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Differential requirement for proliferating cell nuclear antigen in 5' and 3' nick-directed excision in human mismatch repair

21 January 2018

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DNA polymerase delta is required for human mismatch repair in vitro

21 January 2018

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MSH2-MSH6 stimulates DNA polymerase eta, suggesting a role for A:T mutations in antibody genes

21 January 2018

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Steady-state regulation of the human DNA mismatch repair system.

21 January 2018

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Decreased Expression of the DNA Mismatch Repair Gene Mlh1 under Hypoxic Stress in Mammalian Cells

21 January 2018

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HIF-1alpha induces genetic instability by transcriptionally downregulating MutSalpha expression.

21 January 2018

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Identification of the mismatch repair genes PMS2 and MLH1 as p53 target genes by using serial analysis of binding elements

21 January 2018

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Bcl-2 expression suppresses mismatch repair activity through inhibition of E2F transcriptional activity

21 January 2018

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Dimerization of MLH1 and PMS2 Limits Nuclear Localization of MutLα

21 January 2018

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ATM-mediated stabilization of hMutL DNA mismatch repair proteins augments p53 activation during DNA damage

21 January 2018

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Nuclear translocation of mismatch repair proteins MSH2 and MSH6 as a response of cells to alkylating agents

21 January 2018

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Phosphorylation of mismatch repair proteins MSH2 and MSH6 affecting MutSalpha mismatch-binding activity

21 January 2018

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Implication of protein kinase C in the regulation of DNA mismatch repair protein expression and function

21 January 2018

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hMutS alpha is protected from ubiquitin-proteasome-dependent degradation by atypical protein kinase C zeta phosphorylation

21 January 2018

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Cadmium is a mutagen that acts by inhibiting mismatch repair.

21 January 2018

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Cadmium inhibits the functions of eukaryotic MutS complexes.

21 January 2018

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Loss of ATM sensitizes against O6-methylguanine triggered apoptosis, SCEs and chromosomal aberrations

21 January 2018

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Mismatch repair-dependent G2 checkpoint induced by low doses of SN1 type methylating agents requires the ATR kinase

21 January 2018

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Methylation-induced G2/M arrest requires a full complement of the mismatch repair protein hMLH1

21 January 2018

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MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation

21 January 2018

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ATR functions as a gene dosage-dependent tumor suppressor on a mismatch repair-deficient background

21 January 2018

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The p38 Mitogen-Activated Protein Kinase Pathway Links the DNA Mismatch Repair System to the G2 Checkpoint and to Resistance to Chemotherapeutic DNA-Methylating Agents

21 January 2018

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Apoptotic signaling in response to a single type of DNA lesion, O(6)-methylguanine.

21 January 2018

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Apoptosis triggered by DNA damage O6-methylguanine in human lymphocytes requires DNA replication and is mediated by p53 and Fas/CD95/Apo-1.

21 January 2018

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Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin

21 January 2018

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Mismatch repair proteins are activators of toxic responses to chromium-DNA damage

21 January 2018

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Mismatch repair proficiency and in vitro response to 5-fluorouracil

21 January 2018

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Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer

21 January 2018

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Use of 5-fluorouracil and survival in patients with microsatellite-unstable colorectal cancer

21 January 2018

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The mismatch repair complex hMutS alpha recognizes 5-fluorouracil-modified DNA: implications for chemosensitivity and resistance

21 January 2018

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DNA mismatch repair-dependent response to fluoropyrimidine-generated damage.

21 January 2018

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Mismatch repair gene PMS2: disease-causing germline mutations are frequent in patients whose tumors stain negative for PMS2 protein, but paralogous genes obscure mutation detection and interpretation

21 January 2018

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Immunohistochemical analysis reveals high frequency of PMS2 defects in colorectal cancer

21 January 2018

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HNPCC mutations in hMSH2 result in reduced hMSH2-hMSH6 molecular switch functions

21 January 2018

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Lynch syndrome: form, function, proteins, and basketball

21 January 2018

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The interaction of the human MutL homologues in hereditary nonpolyposis colon cancer

21 January 2018

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hMRE11 deficiency leads to microsatellite instability and defective DNA mismatch repair

21 January 2018

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DNA mismatch repair: MutS structures bound to mismatches.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IJC.22023

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14 August 2017

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