(Q44729054)

5 December 2017

title

Apoptosis triggered by DNA damage O6-methylguanine in human lymphocytes requires DNA replication and is mediated by p53 and Fas/CD95/Apo-1. (English)

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5 December 2017

1

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5 December 2017

Manuela Baumgartner

2

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5 December 2017

Bernd Kaina

series ordinal

3

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5 December 2017

language of work or name

English

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publication date

1 January 2004

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5 December 2017

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5 December 2017

volume

23

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5 December 2017

issue

2

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5 December 2017

page(s)

359-367

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Induction of DNA breaks and apoptosis in crosslink-hypersensitive V79 cells by the cytostatic drug beta-D-glucosyl-ifosfamide mustard

5 December 2017

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Human MutSalpha recognizes damaged DNA base pairs containing O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adduct

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Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents.

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Contribution of O6-alkylguanine and N-alkylpurines to the formation of sister chromatid exchanges, chromosomal aberrations, and gene mutations: new insights gained from studies of genetically engineered mammalian cell lines

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An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair.

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Structural features of substituted purine derivatives compatible with depletion of human O6-alkylguanine-DNA alkyltransferase

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DNA Double-stranded Breaks Induce Histone H2AX Phosphorylation on Serine 139

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A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

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Distribution of methyl and ethyl adducts following alkylation with monofunctional alkylating agents

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7 January 2021

Overexpression of N-methylpurine-DNA glycosylase in Chinese hamster ovary cells renders them more sensitive to the production of chromosomal aberrations by methylating agents--a case of imbalanced DNA repair

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7 January 2021

Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer

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7 January 2021

Correlation between cellular radiosensitivity and non-repaired double-strand breaks studied in nine mammalian cell lines

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7 January 2021

Mismatch G-T binding activity and MSH2 expression is quantitatively related to sensitivity of cells to methylating agents

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7 January 2021

Cisplatin-induced apoptosis in 43-3B and 27-1 cells defective in nucleotide excision repair

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7 January 2021

Ultraviolet light-induced DNA damage triggers apoptosis in nucleotide excision repair-deficient cells via Bcl-2 decline and caspase-3/-8 activation

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7 January 2021

Cell proliferation and DNA breaks are involved in ultraviolet light-induced apoptosis in nucleotide excision repair-deficient Chinese hamster cells

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7 January 2021

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7 January 2021

A role for mismatch repair in production of chromosome aberrations by methylating agents in human cells

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7 January 2021

Long-time expression of DNA repair enzymes MGMT and APE in human peripheral blood mononuclear cells.

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7 January 2021

Caspase 8 activation independent of Fas (CD95/APO-1) signaling may mediate killing of B-chronic lymphocytic leukemia cells by cytotoxic drugs or gamma radiation

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7 January 2021

The interrelationship between SCE induction, cell survival, mutagenesis, aberration formation and DNA synthesis inhibition in V79 cells treated with N-methyl-N-nitrosourea or N-methyl-N'-nitro-N-nitrosoguanidine

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7 January 2021

Transfection and expression of human O6-methylguanine-DNA methyltransferase (MGMT) cDNA in Chinese hamster cells: the role of MGMT in protection against the genotoxic effects of alkylating agents

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7 January 2021

Chromosomal instability, reproductive cell death and apoptosis induced by O6-methylguanine in Mex−, Mex+ and methylation-tolerant mismatch repair compromised cells: facts and models

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7 January 2021

DNA damage tolerance, mismatch repair and genome instability

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7 January 2021

Mismatch binding proteins and tolerance to alkylating agents in human cells

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7 January 2021

DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1.

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7 January 2021

DNA double-strand breaks trigger apoptosis in p53-deficient fibroblasts

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7 January 2021

Sustained activation of JNK/p38 MAPK pathways in response to cisplatin leads to Fas ligand induction and cell death in ovarian carcinoma cells

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7 January 2021

O6-alkylguanine-DNA alkyltransferase: role in carcinogenesis and chemotherapy

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7 January 2021

O6-alkylguanine DNA lesions trigger apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207080

7 January 2021

p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs

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7 January 2021

The CD95(APO-1/Fas) DISC and beyond

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207080

7 January 2021

Radiation-induced transcription factor activation in the rat cerebral cortex

1 reference

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7 January 2021

Alkylation-induced apoptosis of embryonic stem cells in which the gene for DNA-repair, methyltransferase, had been disrupted by gene targeting.

1 reference

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207080

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5 December 2017

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