(Q36532509)

14 August 2017

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title

Hypoxia and HIF-1alpha in chondrogenesis (English)

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14 August 2017

main subject

cartilage development

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Ernestina Schipani

1

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14 August 2017

language of work or name

English

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publication date

1 April 2006

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Annals of the New York Academy of Sciences

14 August 2017

number of pages

8

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based on heuristic

inferred from page(s)

published in

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14 August 2017

volume

1068

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14 August 2017

page(s)

66-73

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The biology of hypoxia: the role of oxygen sensing in development, normal function, and disease

14 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1346.009

The complexities of skeletal biology

21 January 2018

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Toward a molecular understanding of skeletal development

21 January 2018

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Developmental regulation of the growth plate

21 January 2018

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PTHrP, PTH, and the PTH/PTHrP receptor in endochondral bone development.

21 January 2018

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MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes

21 January 2018

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Targeting HIF-1 for cancer therapy

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HIF-1 as a target for drug development

21 January 2018

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How oxygen makes its presence felt

21 January 2018

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Structure of an HIF-1alpha -pVHL complex: hydroxyproline recognition in signaling

21 January 2018

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Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1alpha

21 January 2018

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The von Hippel-Lindau tumour suppressor protein: new perspectives

21 January 2018

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Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1alpha

21 January 2018

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The hypoxic tumor microenvironment and gene expression

21 January 2018

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Genetic analysis of pathways regulated by the von Hippel-Lindau tumor suppressor in Caenorhabditis elegans

21 January 2018

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HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

21 January 2018

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Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

21 January 2018

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Defective placental vasculogenesis causes embryonic lethality in VHL-deficient mice

21 January 2018

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Deletion of Vhlh in chondrocytes reduces cell proliferation and increases matrix deposition during growth plate development.

21 January 2018

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HIF-1alpha controls extracellular matrix synthesis by epiphyseal chondrocytes

21 January 2018

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The biology of VEGF and its receptors

21 January 2018

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Expression of VEGF isoforms by epiphyseal chondrocytes during low-oxygen tension is HIF-1 alpha dependent.

21 January 2018

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VEGFA is necessary for chondrocyte survival during bone development

21 January 2018

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VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation

21 January 2018

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Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188.

21 January 2018

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Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal development

21 January 2018

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Tissue specific regulation of VEGF expression during bone development requires Cbfa1/Runx2.

21 January 2018

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Loss of HIF-1alpha in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis.

21 January 2018

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BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis

21 January 2018

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Vhlh gene deletion induces Hif-1-mediated cell death in thymocytes

21 January 2018

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Identification of the hypoxia-inducible factor 1 alpha-responsive HGTD-P gene as a mediator in the mitochondrial apoptotic pathway

21 January 2018

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Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia

21 January 2018

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Investigating hypoxic tumor physiology through gene expression patterns

21 January 2018

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Hypoxia-inducible factor 1alpha is essential for cell cycle arrest during hypoxia

21 January 2018

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21 January 2018

Identifiers

DOI

10.1196/ANNALS.1346.009

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14 August 2017

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