(Q44108492)

29 November 2017

Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1alpha (English)

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29 November 2017

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4

Amato J Giaccia

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29 November 2017

Denise A Chan

1

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29 November 2017

Patrick D Sutphin

series ordinal

2

1 reference

29 November 2017

Nicholas C Denko

series ordinal

3

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29 November 2017

language of work or name

English

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publication date

16 August 2002

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Journal of Biological Chemistry

29 November 2017

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29 November 2017

277

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29 November 2017

40112-40117

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29 November 2017

42

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Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

29 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206922200

Oxygen sensing and molecular adaptation to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206922200

A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206922200

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206922200

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206922200

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206922200

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206922200

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206922200

Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206922200

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206922200

Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206922200

Inhibitory effect of YC-1 on the hypoxic induction of erythropoietin and vascular endothelial growth factor in Hep3B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206922200

Heat induction of the unphosphorylated form of hypoxia-inducible factor-1alpha is dependent on heat shock protein-90 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206922200

Tumour suppression by the human von Hippel-Lindau gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206922200

Development of a hypoxia-responsive vector for tumor-specific gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206922200

Induction of HIF-1alpha in response to hypoxia is instantaneous

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206922200

Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206922200

Modulation of Akt kinase activity by binding to Hsp90

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206922200

Cell density mediated pericellular hypoxia leads to induction of HIF-1alpha via nitric oxide and Ras/MAP kinase mediated signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206922200

21 January 2018

Identifiers

DOI

10.1074/JBC.M206922200

1 reference

29 November 2017

1 reference