(Q36544874)

14 August 2017

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title

Regulation of drug metabolism and disposition during inflammation and infection (English)

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14 August 2017

Kenneth W Renton

1

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14 August 2017

language of work or name

English

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publication date

1 December 2005

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Expert Opinion on Drug Metabolism & Toxicology

14 August 2017

published in

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14 August 2017

volume

1

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14 August 2017

issue

4

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14 August 2017

page(s)

629-640

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Cytochrome P450 regulation and drug biotransformation during inflammation and infection

14 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Mechanisms of cytochrome P450 regulation by inflammatory mediators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Regulation of cytochromes P450 during inflammation and infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Alteration of drug biotransformation and elimination during infection and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Depression of hepatic cytochrome P-450-dependent monooxygenase systems with administered interferon inducing agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Interleukin-6 down regulates the expression of transcripts encoding cytochrome P450 IA1, IA2 and IIIA3 in human hepatoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Influence of cytokines and growth factors on distinct steroidogenic enzymes in vitro: a short tabular data collection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Comparative effects of cytokines on constitutive and inducible expression of the gene encoding for the cytochrome P450 3A6 isoenzyme in cultured rabbit hepatocytes: consequences on progesterone 6beta-hydroxylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Modulation of constitutive and inducible hepatic cytochrome(s) P-450 by interferon beta in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Effects of interleukin-6 on cytochrome P450-dependent mixed-function oxidases in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Cytochrome P450 and antioxidant activity in interleukin-6 knockout mice after induction of the acute-phase response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Transcriptional and post-transcriptional suppression of P450IIC11 and P450IIC12 by inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Interferon-mediated changes in the expression of CYP1A1 in human B lymphoblastoid (AHH-1 TK +/-) cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

The effect of IFN-α-Con1 on hepatic cytochrome P-450 and protein synthesis and degradation in hepatic microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Down-regulation of cytochrome P450 1A1 gene promoter by oxidative stress. Critical contribution of nuclear factor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Suppression of CYP2C11 gene transcription by interleukin-1 mediated by NF-kappaB binding at the transcription start site

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Toll-like receptor-4 regulation of hepatic Cyp3a11 metabolism in a mouse model of LPS-induced CNS inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Enhanced induction of cytochrome P450 enzymes and CAR binding in TNF (p55(-/-)/p75(-/-)) double receptor knockout mice following phenobarbital treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Lipopolysaccharide and Cecal Ligation/Puncture Differentially Affect the Subcellular Distribution of the Pregnane X Receptor but Consistently Cause Suppression of Its Target Genes CYP3A

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Reduction in cytochrome P-450 enzyme expression is associated with repression of CAR (constitutive androstane receptor) and PXR (pregnane X receptor) in mouse liver during the acute phase response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Mechanisms of down-regulation of CYP2E1 expression by inflammatory cytokines in rat hepatoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Altered theophylline pharmacokinetics during acute respiratory viral illness

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Cytochrome P450 inactivation by serum from humans with a viral infection and serum from rabbits with a turpentine-induced inflammation: the role of cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Interleukin-1beta, interleukin-6, tumour necrosis factor-alpha and interferon-gamma released by a viral infection and an aseptic inflammation reduce CYP1A1, 1A2 and 3A6 expression in rabbit hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

The effect of fever on antipyrine metabolism in children

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Altered patterns of drug metabolism in patients with acquired immunodeficiency syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Hepatitis A impairs the function of human hepatic CYP2A6 in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Effect of interferon alpha-ribavirin bitherapy on cytochrome P450 1A2 and 2D6 and N-acetyltransferase-2 activities in patients with chronic active hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Genotype and phenotype of cytochrome P450 2D6 in human immunodeficiency virus-positive patients and patients with acquired immunodeficiency syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Long-term culture of adult rat hepatocyte spheroids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Ontogenesis of CYP2C-dependent arachidonic acid metabolism in the human liver: relationship with sudden infant death syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Cytochrome P-450 expression in sudden infant death syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Pharmacokinetic and pharmacodynamic considerations when treating patients with sepsis and septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Endotoxin administration to humans inhibits hepatic cytochrome P450-mediated drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Endotoxin depresses hepatic cytochrome P450-mediated drug metabolism in women

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Failure of critically ill patients to metabolise midazolam.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

What changes drug metabolism in critically ill patients?--II Serum inhibits the metabolism of midazolam in human microsomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Impairment of cytochrome P-450-dependent liver activity in cirrhotic patients with Helicobacter pylori infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Cytochrome P450 3A4 activity after surgical stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Plasma levels of TNF-alpha and IL-6 are inversely related to cytochrome P450-dependent drug metabolism in patients with congestive heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Hypoxia-induced down-regulation of CYP1A1/1A2 and up-regulation of CYP3A6 involves serum mediators

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Decreased dromotropic response to verapamil despite pronounced increased drug concentration in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

CYP7B expression and activity in fibroblast-like synoviocytes from patients with rheumatoid arthritis: regulation by proinflammatory cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Inflammatory response: an unrecognised source of variability in the pharmacokinetics and pharmacodynamics of cancer chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Hepatic cytochrome P450 3A drug metabolism is reduced in cancer patients who have an acute-phase response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

The influence of inflammatory cytokines on estrogen production and cell proliferation in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Cytokines and their receptors in the central nervous system: physiology, pharmacology, and pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Lipopolysaccharide evokes the modulation of brain cytochrome P4501A in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Decrease in brain cytochrome P450 enzyme activities during infection and inflammation of the central nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Brain inflammation enhances 1-methyl-4-phenylpyridinium-evoked neurotoxicity in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Mechanism of decrease in levels of hepatic P450 isozymes induced by intracerebral endotoxin: independence from sympathetic nervous and adrenocortical systems.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

The signal transduction pathways involved in hepatic cytochrome P450 regulation in the rat during a lipopolysaccharide-induced model of central nervous system inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Modulation of hepatic cytochrome P450 during Listeria monocytogenes infection of the brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Downregulation of mdr1a expression in the brain and liver during CNS inflammation alters the in vivo disposition of digoxin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Modulation of cytochrome P450 by inflammation in astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Decreased expression and activity of P-glycoprotein in rat liver during acute inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Regulation of the hepatic multidrug resistance gene expression by endotoxin and inflammatory cytokines in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Inflammatory cytokines, but not bile acids, regulate expression of murine hepatic anion transporters in endotoxemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Decreased expression of P-glycoprotein in interleukin-1beta and interleukin-6 treated rat hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Cytokine regulation of P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Effect of recombinant interleukin-2 pretreatment on oral and intravenous digoxin pharmacokinetics and P-glycoprotein activity in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Recombinant interleukin-2 treatment decreases P-glycoprotein activity and paclitaxel metabolism in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Biochemical mechanisms of cyclosporine neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Hepatic cytochrome P450 down-regulation during aseptic inflammation in the mouse is interleukin 6 dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

21 January 2018

Identifiers

DOI

10.1517/17425255.1.4.629

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14 August 2017

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