(Q36544874)

14 August 2017

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title

Regulation of drug metabolism and disposition during inflammation and infection (English)

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14 August 2017

Kenneth W Renton

1

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14 August 2017

language of work or name

English

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publication date

1 December 2005

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Expert Opinion on Drug Metabolism & Toxicology

14 August 2017

published in

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14 August 2017

volume

1

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14 August 2017

issue

4

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14 August 2017

page(s)

629-640

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Cytochrome P450 regulation and drug biotransformation during inflammation and infection

14 August 2017

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Interleukin-1beta, interleukin-6, tumour necrosis factor-alpha and interferon-gamma released by a viral infection and an aseptic inflammation reduce CYP1A1, 1A2 and 3A6 expression in rabbit hepatocytes.

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Pharmacokinetic and pharmacodynamic considerations when treating patients with sepsis and septic shock

21 January 2018

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21 January 2018

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Endotoxin depresses hepatic cytochrome P450-mediated drug metabolism in women

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Brain inflammation enhances 1-methyl-4-phenylpyridinium-evoked neurotoxicity in rats

21 January 2018

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Mechanism of decrease in levels of hepatic P450 isozymes induced by intracerebral endotoxin: independence from sympathetic nervous and adrenocortical systems

21 January 2018

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The signal transduction pathways involved in hepatic cytochrome P450 regulation in the rat during a lipopolysaccharide-induced model of central nervous system inflammation

21 January 2018

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Modulation of hepatic cytochrome P450 during Listeria monocytogenes infection of the brain

21 January 2018

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Downregulation of mdr1a expression in the brain and liver during CNS inflammation alters the in vivo disposition of digoxin.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Modulation of cytochrome P450 by inflammation in astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Decreased expression and activity of P-glycoprotein in rat liver during acute inflammation.

21 January 2018

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Regulation of the hepatic multidrug resistance gene expression by endotoxin and inflammatory cytokines in mice.

21 January 2018

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Inflammatory cytokines, but not bile acids, regulate expression of murine hepatic anion transporters in endotoxemia.

21 January 2018

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Decreased expression of P-glycoprotein in interleukin-1beta and interleukin-6 treated rat hepatocytes.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Cytokine regulation of P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Effect of recombinant interleukin-2 pretreatment on oral and intravenous digoxin pharmacokinetics and P-glycoprotein activity in mice.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Recombinant interleukin-2 treatment decreases P-glycoprotein activity and paclitaxel metabolism in mice.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Biochemical mechanisms of cyclosporine neurotoxicity

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.1.4.629

Hepatic cytochrome P450 down-regulation during aseptic inflammation in the mouse is interleukin 6 dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.629

21 January 2018

Identifiers

DOI

10.1517/17425255.1.4.629

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14 August 2017

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