(Q36544966)

14 August 2017

1 reference

title

Role of the liver-specific transporters OATP1B1 and OATP1B3 in governing drug elimination (English)

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14 August 2017

3

Alex Sparreboom

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14 August 2017

Nicola F Smith

1

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14 August 2017

William D Figg

series ordinal

2

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14 August 2017

language of work or name

English

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publication date

1 October 2005

1 reference

Expert Opinion on Drug Metabolism & Toxicology

14 August 2017

published in

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14 August 2017

volume

1

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14 August 2017

issue

3

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14 August 2017

page(s)

429-445

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Unmasking the dynamic interplay between efflux transporters and metabolic enzymes.

14 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Mechanisms of resistance to anticancer drugs: the role of the polymorphic ABC transporters ABCB1 and ABCG2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Expression cloning of a rat liver Na(+)-independent organic anion transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Organic anion transporting polypeptides of the OATP/ SLC21 family: phylogenetic classification as OATP/ SLCO superfamily, new nomenclature and molecular/functional properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

The superfamily of organic anion transporting polypeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Identification of a novel gene family encoding human liver-specific organic anion transporter LST-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

A novel human hepatic organic anion transporting polypeptide (OATP2). Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Localization and genomic organization of a new hepatocellular organic anion transporting polypeptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

LST-2, a human liver-specific organic anion transporter, determines methotrexate sensitivity in gastrointestinal cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Underexpression of mRNA in human hepatocellular carcinoma focusing on eight loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Detection of the human organic anion transporters SLC21A6 (OATP2) and SLC21A8 (OATP8) in liver and hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

The human organic anion transporting polypeptide 8 (SLCO1B3) gene is transcriptionally repressed by hepatocyte nuclear factor 3beta in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Hepatobiliary transporter expression in human hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Cloning of the full-length coding sequence of rat liver-specific organic anion transporter-1 (rlst-1) and a splice variant and partial characterization of the rat lst-1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Molecular characterization and functional regulation of a novel rat liver-specific organic anion transporter rlst-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Full-length cDNA cloning and genomic organization of the mouse liver-specific organic anion transporter-1 (lst-1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Localization of organic anion transporting polypeptide 4 (Oatp4) in rat liver and comparison of its substrate specificity with Oatp1, Oatp2 and Oatp3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Tissue expression, ontogeny, and inducibility of rat organic anion transporting polypeptide 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Tissue distribution and ontogeny of mouse organic anion transporting polypeptides (Oatps).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Localization of organic anion transporting polypeptides in the rat and human ciliary body epithelium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Hepatic uptake of cholecystokinin octapeptide by organic anion-transporting polypeptides OATP4 and OATP8 of rat and human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Contribution of OATP2 (OATP1B1) and OATP8 (OATP1B3) to the hepatic uptake of pitavastatin in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Mutations in the SLCO1B3 gene affecting the substrate specificity of the hepatocellular uptake transporter OATP1B3 (OATP8).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Contribution of organic anion transporting polypeptide OATP-C to hepatic elimination of the opioid pentapeptide analogue [D-Ala2, D-Leu5]-enkephalin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Identification of OATP1B3 as a high-affinity hepatocellular transporter of paclitaxel

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Differential interaction of 3-hydroxy-3-methylglutaryl-coa reductase inhibitors with ABCB1, ABCC2, and OATP1B1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Inhibition of transporter-mediated hepatic uptake as a mechanism for drug-drug interaction between cerivastatin and cyclosporin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Gemfibrozil and its glucuronide inhibit the organic anion transporting polypeptide 2 (OATP2/OATP1B1:SLC21A6)-mediated hepatic uptake and CYP2C8-mediated metabolism of cerivastatin: analysis of the mechanism of the clinically relevant drug-drug inter

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Role of organic anion transporter OATP1B1 (OATP-C) in hepatic uptake of irinotecan and its active metabolite, 7-ethyl-10-hydroxycamptothecin: in vitro evidence and effect of single nucleotide polymorphisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Hepatic uptake of bilirubin and its conjugates by the human organic anion transporter SLC21A6

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Rosuvastatin pharmacokinetics in heart transplant recipients administered an antirejection regimen including cyclosporine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

The effect of gemfibrozil on the pharmacokinetics of rosuvastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Human organic anion transporting polypeptide-C (SLC21A6) is a major determinant of rifampin-mediated pregnane X receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Interactions of rifamycin SV and rifampicin with organic anion uptake systems of human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Inhibition of human organic anion transporting polypeptide OATP 1B1 as a mechanism of drug-induced hyperbilirubinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Characterization of the transport of the bicyclic peptide phalloidin by human hepatic transport proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Evaluation of drug-drug interaction in the hepatobiliary and renal transport of drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Potential for conflict of interest in the evaluation of suspected adverse drug reactions: use of cerivastatin and risk of rhabdomyolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Gemfibrozil greatly increases plasma concentrations of cerivastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Gemfibrozil inhibits CYP2C8-mediated cerivastatin metabolism in human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Effects of fibrates on metabolism of statins in human hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Pharmacogenomics--drug disposition, drug targets, and side effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Pharmacogenomics of the OATP and OAT families

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

The genetic polymorphism of drug transporters: functional analysis approaches.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Polymorphisms in OATP-C: identification of multiple allelic variants associated with altered transport activity among European- and African-Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

A naturally occurring mutation in the SLC21A6 gene causing impaired membrane localization of the hepatocyte uptake transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Catalog of 258 single-nucleotide polymorphisms (SNPs) in genes encoding three organic anion transporters, three organic anion-transporting polypeptides, and three NADH:ubiquinone oxidoreductase flavoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Genetic polymorphisms of human organic anion transporters OATP-C (SLC21A6) and OATP-B (SLC21A9): allele frequencies in the Japanese population and functional analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: consequences for pravastatin pharmacokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

A novel variant allele of OATP-C (SLCO1B1) found in a Japanese patient with pravastatin-induced myopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Functional analysis of single nucleotide polymorphisms of hepatic organic anion transporter OATP1B1 (OATP-C).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Evidence for inverse effects of OATP-C (SLC21A6) 5 and 1b haplotypes on pravastatin kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Acute effects of pravastatin on cholesterol synthesis are associated with SLCO1B1 (encoding OATP1B1) haplotype *17.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Effect of genetic polymorphism of OATP-C (SLCO1B1) on lipid-lowering response to HMG-CoA reductase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Fexofenadine pharmacokinetics are associated with a polymorphism of the SLCO1B1 gene (encoding OATP1B1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Polymorphic organic anion transporting polypeptide 1B1 is a major determinant of repaglinide pharmacokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Risk factors for severe hyperbilirubinemia in neonates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Hepatic transport of PKI166, an epidermal growth factor receptor kinase inhibitor of the pyrrolo-pyrimidine class, and its main metabolite, ACU154.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Role of organic anion-transporting polypeptides, OATP-A, OATP-C and OATP-8, in the human placenta-maternal liver tandem excretory pathway for foetal bilirubin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Hepatic uptake of the novel antifungal agent caspofungin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Identification of phalloidin uptake systems of rat and human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Carriers involved in targeting the cytostatic bile acid-cisplatin derivatives cis-diammine-chloro-cholylglycinate-platinum(II) and cis-diammine-bisursodeoxycholate-platinum(II) toward liver cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Organic anion transporting polypeptides expressed in liver and brain mediate uptake of microcystin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Functional characterization of human organic anion transporting polypeptide B (OATP-B) in comparison with liver-specific OATP-C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Involvement of organic anion transporting polypeptides in the transport of troglitazone sulfate: implications for understanding troglitazone hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

Interactions of glycyrrhizin with organic anion transporting polypeptides of rat and human liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.3.429

21 January 2018

Identifiers

DOI

10.1517/17425255.1.3.429

1 reference

release_bakgyenyxrfi7lr5jgbymb6hli

14 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/bakgyenyxrfi7lr5jgbymb6hli

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference