(Q36120816)

12 August 2017

1 reference

title

Mechanisms of resistance to anticancer drugs: the role of the polymorphic ABC transporters ABCB1 and ABCG2. (English)

1 reference

12 August 2017

6

Alex Sparreboom

1 reference

12 August 2017

3

Jaap Verweij

1 reference

12 August 2017

Erin R Lepper

1

1 reference

12 August 2017

Kees Nooter

series ordinal

2

1 reference

12 August 2017

Milin R Acharya

series ordinal

4

1 reference

12 August 2017

William D Figg

series ordinal

5

1 reference

12 August 2017

publication date

1 March 2005

1 reference

12 August 2017

1 reference

12 August 2017

volume

6

1 reference

12 August 2017

issue

2

1 reference

12 August 2017

page(s)

115-138

1 reference

From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance.

12 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

A family of drug transporters: the multidrug resistance-associated proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

The human ATP-binding cassette (ABC) transporter superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Overview: ABC transporters and human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Role of P-glycoprotein in pharmacokinetics: clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Absence or pharmacological blocking of placental P-glycoprotein profoundly increases fetal drug exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid drug-permeability barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

The influence of MDR1 polymorphisms on P-glycoprotein expression and function in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Polymorphisms in human MDR1 (P-glycoprotein): recent advances and clinical relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Structural model of ATP-binding proteins associated with cystic fibrosis, multidrug resistance and bacterial transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Natural variation in human membrane transporter genes reveals evolutionary and functional constraints

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

The HUGO Mutation Database Initiative. Human Genome Organization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Multidrug resistance in cancer: role of ATP-dependent transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Biochemistry of multidrug resistance mediated by the multidrug transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Biochemical, cellular, and pharmacological aspects of the multidrug transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

The importance of drug-transporting P-glycoproteins in toxicology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

The pharmacological role of P-glycoprotein in the intestinal epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

The physiological function of drug-transporting P-glycoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Modulation of oral bioavailability of anticancer drugs: from mouse to man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

A physiologic function for p-glycoprotein (MDR-1) during the migration of dendritic cells from skin via afferent lymphatic vessels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

21 January 2018

Oral delivery of taxanes

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Coadministration of cyclosporine strongly enhances the oral bioavailability of docetaxel

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Promoter characterization and genomic organization of the human breast cancer resistance protein (ATP-binding cassette transporter G2) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

The role of half-transporters in multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

The Role of ABC Transporters in Clinical Practice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

A multidrug resistance transporter from human MCF-7 breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Phenomenology and scientific progress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Atypical multidrug resistance: breast cancer resistance protein messenger RNA expression in mitoxantrone-selected cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Characterization of oligomeric human half-ABC transporter ATP-binding cassette G2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Bcrp1 gene expression is required for normal numbers of side population stem cells in mice, and confers relative protection to mitoxantrone in hematopoietic cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

A functional assay for detection of the mitoxantrone resistance protein, MXR (ABCG2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Multidrug resistance in cancer chemotherapy and xenobiotic protection mediated by the half ATP-binding cassette transporter ABCG2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Role reversal for anticancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Multidrug resistance and cancer: the role of the human ABC transporter ABCG2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Increased oral bioavailability of topotecan in combination with the breast cancer resistance protein and P-glycoprotein inhibitor GF120918.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Improvement of oral drug treatment by temporary inhibition of drug transporters and/or cytochrome P450 in the gastrointestinal tract and liver: an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Reversal of resistance by GF120918 in cell lines expressing the ABC half-transporter, MXR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Breast cancer resistance protein exports sulfated estrogens but not free estrogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Estrone and 17beta-estradiol reverse breast cancer resistance protein-mediated multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Identification of a novel estrogen response element in the breast cancer resistance protein (ABCG2) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Sterol transport by the human breast cancer resistance protein (ABCG2) expressed in Lactococcus lactis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Functional characterization of a glycine 185-to-valine substitution in human P-glycoprotein by using a vaccinia-based transient expression system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

ABC drug transporters: hereditary polymorphisms and pharmacological impact in MDR1, MRP1 and MRP2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Three hundred twenty-six genetic variations in genes encoding nine members of ATP-binding cassette, subfamily B (ABCB/MDR/TAP), in the Japanese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Genetic polymorphisms of the human MDR1 drug transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Pharmacogenomics--drug disposition, drug targets, and side effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Functional characterization of coding polymorphisms in the human MDR1 gene using a vaccinia virus expression system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Identification of functionally variant MDR1 alleles among European Americans and African Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

The pregnane X receptor binds to response elements in a genomic context-dependent manner, and PXR activator rifampicin selectively alters the binding among target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Haplotype-oriented genetic analysis and functional assessment of promoter variants in the MDR1 (ABCB1) gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Single-nucleotide polymorphism (SNP) analysis in the ABC half-transporter ABCG2 (MXR/BCRP/ABCP1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Catalog of 605 single-nucleotide polymorphisms (SNPs) among 13 genes encoding human ATP-binding cassette transporters: ABCA4, ABCA7, ABCA8, ABCD1, ABCD3, ABCD4, ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and ABCG8

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Natural allelic variants of breast cancer resistance protein (BCRP) and their relationship to BCRP expression in human intestine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

ABCG2 pharmacogenetics: ethnic differences in allele frequency and assessment of influence on irinotecan disposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Genetic variation in the ATP-binding Cassette Transporter gene ABCG2 (BCRP) in a Swedish population

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Single nucleotide polymorphisms result in impaired membrane localization and reduced atpase activity in multidrug transporter ABCG2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Eight novel single nucleotide polymorphisms in ABCG2/BCRP in Japanese cancer patients administered irinotacan

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Functional analysis of SNPs variants of BCRP/ABCG2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Functional assessment of ABCG2 (BCRP) gene polymorphisms to protein expression in human placenta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Mutations at amino-acid 482 in the ABCG2 gene affect substrate and antagonist specificity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Pheophorbide a is a specific probe for ABCG2 function and inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

A functional study on polymorphism of the ATP-binding cassette transporter ABCG2: critical role of arginine-482 in methotrexate transport.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Role of human MDR1 gene polymorphism in bioavailability and interaction of digoxin, a substrate of P-glycoprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

The effect of rifampin treatment on intestinal expression of human MRP transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Complementary and alternative medicine: opportunities and challenges for cancer management and research

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

C3435T polymorphism in the MDR1 gene affects the enterocyte expression level of CYP3A4 rather than Pgp in recipients of living-donor liver transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Polymorphisms in the ABC drug transporter gene MDR1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

MDR1 pharmacogenetics: frequency of the C3435T mutation in exon 26 is significantly influenced by ethnicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Frequency of C3435T polymorphism of MDR1 gene in African people

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

CYP3A activity measured by the midazolam test is not related to 3435 C >T polymorphism in the multiple drug resistance transporter gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Genetic polymorphisms in MDR1 and CYP3A4 genes in Asians and the influence of MDR1 haplotypes on cyclosporin disposition in heart transplant recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

A variant 2677A allele of the MDR1 gene affects fexofenadine disposition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Effects of ABCB1 (multidrug resistance transporter) gene mutations on disposition and central nervous effects of loperamide in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Haplotype analysis of ABCB1/MDR1 blocks in a Japanese population reveals genotype-dependent renal clearance of irinotecan

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Explaining interindividual variability of docetaxel pharmacokinetics and pharmacodynamics in Asians through phenotyping and genotyping strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Pharmacogenetics of tipifarnib (R115777) transport and metabolism in cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Biliary transport of irinotecan and metabolites in normal and P-glycoprotein-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Modulation of irinotecan metabolism by ketoconazole

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Evaluation of accelerator mass spectrometry in a human mass balance and pharmacokinetic study-experience with 14C-labeled (R)-6-[amino(4- chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1- methyl-2(1H)-quinolinone (R115777), a far

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Pharmacogenomics of MDR1/ABCB1 gene: the influence on risk and clinical outcome of haematological malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Functional C3435T polymorphism of MDR1 gene: an impact on genetic susceptibility and clinical outcome of childhood acute lymphoblastic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Association between the C3435T MDR1 gene polymorphism and susceptibility for ulcerative colitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

MDR1 Ala893 polymorphism is associated with inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

The C3435T MDR1 gene polymorphism is not associated with susceptibility for ulcerative colitis in Greek population

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Polymorphism in the P-glycoprotein drug transporter MDR1 gene: a possible link between environmental and genetic factors in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Analysis of MDR1 haplotypes in Parkinson's disease in a white population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

ABCB1 C3435T and G2677T/A polymorphism decreased the risk for steroid-induced osteonecrosis of the femoral head after kidney transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Association between ABCB1 (multidrug resistance transporter) genotype and post-liver transplantation renal dysfunction in patients receiving calcineurin inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

MDR1 gene polymorphisms and phase 1 viral decay during HIV-1 infection: an adult AIDS Clinical Trials Group study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

MDR1 genetic polymorphism does not modify either cell permissiveness to HIV-1 or disease progression before treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Diflomotecan pharmacokinetics in relation to ABCG2 421C>A genotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Dosing strategies for anticancer drugs: the good, the bad and body-surface area

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Imatinib mesylate (STI571) is a substrate for the breast cancer resistance protein (BCRP)/ABCG2 drug pump

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Reversal of P-glycoprotein mediated multidrug resistance by a newly synthesized 1,4-benzothiazipine derivative, JTV-519.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

A retrovirus carrying an MDR1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Interaction of tyrosine kinase inhibitors with the human multidrug transporter proteins, MDR1 and MRP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

CPT-11 sensitivity in relation to the expression of P170-glycoprotein and multidrug resistance-associated protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

The molecular interaction of the high affinity reversal agent XR9576 with P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

VX-710 (biricodar) increases drug retention and enhances chemosensitivity in resistant cells overexpressing P-glycoprotein, multidrug resistance protein, and breast cancer resistance protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

ABCG2 mediates differential resistance to SN-38 (7-ethyl-10-hydroxycamptothecin) and homocamptothecins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Growth inhibitory effect of a new camptothecin analog, DX-8951f, on various drug-resistant sublines including BCRP-mediated camptothecin derivative-resistant variants derived from the human lung cancer cell line PC-6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

A multidrug efflux phenotype mutant of Streptococcus pyogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Imatinib mesylate is a potent inhibitor of the ABCG2 (BCRP) transporter and reverses resistance to topotecan and SN-38 in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

HIV protease inhibitors are inhibitors but not substrates of the human breast cancer resistance protein (BCRP/ABCG2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Broad-spectrum modulation of ATP-binding cassette transport proteins by the taxane derivatives ortataxel (IDN-5109, BAY 59-8862) and tRA96023.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Enhanced exposure of phosphatidylserine in human gastric carcinoma cells overexpressing the half-size ABC transporter BCRP (ABCG2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Breast cancer resistance protein directly confers SN-38 resistance of lung cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Acquired resistance of human T cells to sulfasalazine: stability of the resistant phenotype and sensitivity to non-related DMARDs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

MDR1 polymorphisms G2677T in exon 21 and C3435T in exon 26 fail to affect rhodamine 123 efflux in peripheral blood lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

The effects of the human MDR1 genotype on the expression of duodenal P-glycoprotein and disposition of the probe drug talinolol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Effect of the mutation (C3435T) at exon 26 of the MDR1 gene on expression level of MDR1 messenger ribonucleic acid in duodenal enterocytes of healthy Japanese subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Modulation of multidrug resistance P-glycoprotein 1 (ABCB1) expression in human heart by hereditary polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Variable expression of P-glycoprotein in the human placenta and its association with mutations of the multidrug resistance 1 gene (MDR1, ABCB1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Common single nucleotide polymorphisms of the MDR1 gene have no influence on its mRNA expression level of normal kidney cortex and renal cell carcinoma in Japanese nephrectomized patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Dexamethasone as a probe for docetaxel clearance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Single nucleotide polymorphisms and outcome in docetaxel-cisplatin-treated advanced non-small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Effects of prednisone and genetic polymorphisms on etoposide disposition in children with acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Prediction of irinotecan pharmacokinetics by use of cytochrome P450 3A4 phenotyping probes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Influence of functional polymorphisms of the MDR1 gene on vincristine pharmacokinetics in childhood acute lymphoblastic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

MDR1 genotypes do not influence the absorption of a single oral dose of 1 mg digoxin in healthy white males

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Effects of grapefruit juice on intestinal P-glycoprotein: evaluation using digoxin in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

C3435T mutation in exon 26 of the human MDR1 gene and cyclosporine pharmacokinetics in healthy subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

MDR1 haplotypes do not affect the steady-state pharmacokinetics of cyclosporine in renal transplant patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

The effect of CYP3A5 and MDR1 polymorphic expression on cyclosporine oral disposition in renal transplant patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

The effect of CYP3A5 and MDR1 (ABCB1) polymorphisms on cyclosporine and tacrolimus dose requirements and trough blood levels in stable renal transplant patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

CYP3A5 and MDR1 genetic polymorphisms and cyclosporine pharmacokinetics after renal transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

MDR-1 C3435T polymorphism influences cyclosporine a dose requirement in liver-transplant recipients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Population pharmacokinetics of cyclosporine in kidney and heart transplant recipients and the influence of ethnicity and genetic polymorphisms in the MDR-1, CYP3A4, and CYP3A5 genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Tacrolimus pharmacogenetics: polymorphisms associated with expression of cytochrome p4503A5 and P-glycoprotein correlate with dose requirement

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Neurotoxicity induced by tacrolimus after liver transplantation: relation to genetic polymorphisms of the ABCB1 (MDR1) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Tacrolimus Dosing in Pediatric Heart Transplant Patients is Related to CYP3A5 and MDR1 Gene Polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Association of the multidrug resistance-1 gene single-nucleotide polymorphisms with the tacrolimus dose requirements in renal transplant recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Tacrolimus dosing in adult lung transplant patients is related to cytochrome P4503A5 gene polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

MDR1 haplotypes derived from exons 21 and 26 do not affect the steady-state pharmacokinetics of tacrolimus in renal transplant patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Influence of CYP3A5 and MDR1 (ABCB1) polymorphisms on the pharmacokinetics of tacrolimus in renal transplant recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

No effect of MDR1 C3435T variant on loperamide disposition and central nervous system effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

A common P-glycoprotein polymorphism is associated with nortriptyline-induced postural hypotension in patients treated for major depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

The MDR1 polymorphisms at exons 21 and 26 predict steroid weaning in pediatric heart transplant patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Warfarin sensitivity related to CYP2C9, CYP3A5, ABCB1 (MDR1) and other factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Influence of polymorphisms within the CX3CR1 and MDR-1 genes on initial antiretroviral therapy response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Digoxin pharmacokinetics and MDR1 genetic polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Association of Multidrug Resistance in Epilepsy with a Polymorphism in the Drug-Transporter GeneABCB1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

Polymorphisms in multidrug resistance 1 (MDR1) gene are associated with refractory Crohn disease and ulcerative colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.2.115

21 January 2018

Identifiers

DOI

10.1517/14622416.6.2.115

1 reference

12 August 2017

1 reference