(Q36545654)

14 August 2017

Navigating the protein fitness landscape with Gaussian processes (English)

1 reference

14 August 2017

1 reference

2

0 references

Frances Arnold

series ordinal

3

object named as

Frances H Arnold

1 reference

14 August 2017

Philip A Romero

1

1 reference

PMCID

3549130

14 August 2017

language of work or name

English

0 references

publication date

31 December 2012

1 reference

Proceedings of the National Academy of Sciences of the United States of America

14 August 2017

1 reference

14 August 2017

110

1 reference

14 August 2017

E193-201

1 reference

14 August 2017

3

1 reference

PMCID

3549130

maintained by WikiProject

14 August 2017

WikiProject Mathematics

0 references

cites work

Structure-Guided Directed Evolution of Highly Selective P450-Based Magnetic Resonance Imaging Sensors for Dopamine and Serotonin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549130

An exciting but challenging road ahead for computational enzyme design

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549130

Directed evolution of a magnetic resonance imaging contrast agent for noninvasive imaging of dopamine

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549130

Exploring protein fitness landscapes by directed evolution

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549130

De novo computational design of retro-aldol enzymes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549130

A diverse family of thermostable cytochrome P450s created by recombination of stabilizing fragments

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549130

Engineering proteinase K using machine learning and synthetic genes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549130

Diversification of catalytic function in a synthetic family of chimeric cytochrome p450s

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549130

Structure-guided recombination creates an artificial family of cytochromes P450.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549130

On the conservative nature of intragenic recombination

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549130

Functional evolution and structural conservation in chimeric cytochromes p450: calibrating a structure-guided approach

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549130

Protein design is NP-hard

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549130

Functional proteins from a random-sequence library

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549130

De novo protein design: fully automated sequence selection

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549130

Expression and enzymatic activity of recombinant cytochrome P450 17 alpha-hydroxylase in Escherichia coli

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549130

An accurate, residue-level, pair potential of mean force for folding and binding based on the distance-scaled, ideal-gas reference state.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549130

Evolution and speciation on holey adaptive landscapes.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549130

Improving catalytic function by ProSAR-driven enzyme evolution.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549130

Thermostabilization of a cytochrome p450 peroxygenase.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549130

High-throughput screen for aromatic hydroxylation

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549130

High-throughput carbon monoxide binding assay for cytochromes p450.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549130

An analysis of approximations for maximizing submodular set functions—I

21 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1215251110

Estimating the prevalence of protein sequences adopting functional enzyme folds

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23277561

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The distribution of fitness effects among beneficial mutations in Fisher's geometric model of adaptation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23277561

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Why are proteins marginally stable?

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23277561

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Maximum entropy sampling

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1073/PNAS.1215251110

Interpolation of Spatial Data

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1073/PNAS.1215251110

Information-Theoretic Regret Bounds for Gaussian Process Optimization in the Bandit Setting

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1073/PNAS.1215251110

Identifiers

DOI

10.1073/PNAS.1215251110

1 reference

14 August 2017

0 references

journals/pnas/RomeroKA13

1 reference

DBLP Dataset 2021-01-02

28 January 2021

1 reference

14 August 2017

1 reference

PMCID

3549130