(Q36557997)

14 August 2017

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title

The many shapes of mitochondrial death (English)

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14 August 2017

L Scorrano

2

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author name string

G M Cereghetti

series ordinal

1

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PubMed ID

16892085

14 August 2017

language of work or name

English

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publication date

1 August 2006

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14 August 2017

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14 August 2017

25

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14 August 2017

4717-4724

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14 August 2017

34

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1209605

14 August 2017

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cites work

Deletion of the OPA1 gene in a dominant optic atrophy family: evidence that haploinsufficiency is the cause of disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

OPA1 R445H mutation in optic atrophy associated with sensorineural deafness.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Release of OPA1 during apoptosis participates in the rapid and complete release of cytochrome c and subsequent mitochondrial fragmentation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Bax/Bak-dependent release of DDP/TIMM8a promotes Drp1-mediated mitochondrial fission and mitoptosis during programmed cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Phosphorylation of BCL-2 regulates ER Ca2+ homeostasis and apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Bcl-2 and Bax exert opposing effects on Ca2+ signaling, which do not depend on their putative pore-forming region

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Disruption of fusion results in mitochondrial heterogeneity and dysfunction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Dysregulation of HSG triggers vascular proliferative disorders

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

OPA1 requires mitofusin 1 to promote mitochondrial fusion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Cell death: critical control points

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Mitochondrial function and actin regulate dynamin-related protein 1-dependent mitochondrial fission.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Mutation spectrum and splicing variants in the OPA1 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

OPA1 (Kjer type) dominant optic atrophy: a novel mitochondrial disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Mitochondrial fission proteins regulate programmed cell death in yeast

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

eOPA1: an online database for OPA1 mutations.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Expression and genetic analysis of XIAP-associated factor 1 (XAF1) in cancer cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Bcl-2 decreases the free Ca2+ concentration within the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

The internal structure of mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Endoplasmic reticulum BIK initiates DRP1-regulated remodelling of mitochondrial cristae during apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Loss of the intermembrane space protein Mgm1/OPA1 induces swelling and localized constrictions along the lengths of mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Sumo1 conjugates mitochondrial substrates and participates in mitochondrial fission

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Dnm1 forms spirals that are structurally tailored to fit mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Mitofusin 1 and 2 play distinct roles in mitochondrial fusion reactions via GTPase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

DRP-1-mediated mitochondrial fragmentation during EGL-1-induced cell death in C. elegans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

hFis1, a novel component of the mammalian mitochondrial fission machinery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Quantitation of mitochondrial dynamics by photolabeling of individual organelles shows that mitochondrial fusion is blocked during the Bax activation phase of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Endophilin B1 is required for the maintenance of mitochondrial morphology

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Human deafness dystonia syndrome is a mitochondrial disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Structural basis of mitochondrial tethering by mitofusin complexes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

C. elegans dynamin-related protein DRP-1 controls severing of the mitochondrial outer membrane

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Evidence that BCL-2 represses apoptosis by regulating endoplasmic reticulum-associated Ca2+ fluxes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Bcl-X(L) affects Ca(2+) homeostasis by altering expression of inositol 1,4,5-trisphosphate receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

The inhibitors of apoptosis: there is more to life than Bcl2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Calcineurin inhibition of dynamin I GTPase activity coupled to nerve terminal depolarization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Separate fusion of outer and inner mitochondrial membranes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Mitochondrial fusion intermediates revealed in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

How mitochondria fuse

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Axonal transport of mitochondria along microtubules and F-actin in living vertebrate neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Dnm1p GTPase-mediated mitochondrial fission is a multi-step process requiring the novel integral membrane component Fis1p

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Activated mitofusin 2 signals mitochondrial fusion, interferes with Bax activation, and reduces susceptibility to radical induced depolarization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Bax-mediated Ca2+ mobilization promotes cytochrome c release during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Bax and Bak promote apoptosis by modulating endoplasmic reticular and mitochondrial Ca2+ stores

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

The human dynamin-related protein OPA1 is anchored to the mitochondrial inner membrane facing the inter-membrane space

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Regulation of cell death: the calcium-apoptosis link

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Propagation of the apoptotic signal by mitochondrial waves

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Mitochondrial fusion and fission in the control of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

OPA1 mutations in patients with autosomal dominant optic atrophy and evidence for semi-dominant inheritance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Reduced loading of intracellular Ca(2+) stores and downregulation of capacitative Ca(2+) influx in Bcl-2-overexpressing cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

The dynamin superfamily: universal membrane tubulation and fission molecules?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Mitochondria as all-round players of the calcium game

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Differential sublocalization of the dynamin-related protein OPA1 isoforms in mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Divide et impera: Ca2+ signals, mitochondrial fission and sensitization to apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Proteins that fuse and fragment mitochondria in apoptosis: con-fissing a deadly con-fusion?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

A distinct pathway remodels mitochondrial cristae and mobilizes cytochrome c during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Mitochondrial dynamics and division in budding yeast

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

A novel mutation of the OPA1 gene in a Japanese family with optic atrophy type 1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Self-regulated cleavage of the mitochondrial intramembrane-cleaving protease PARL yields Pbeta, a nuclear-targeted peptide

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Fzo1, a protein involved in mitochondrial fusion, inhibits apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

The solution structure of human mitochondria fission protein Fis1 reveals a novel TPR-like helix bundle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Drp-1-dependent division of the mitochondrial network blocks intraorganellar Ca2+ waves and protects against Ca2+-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

A frameshift mutation in exon 28 of the OPA1 gene explains the high prevalence of dominant optic atrophy in the Danish population: evidence for a founder effect

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Spectrum, frequency and penetrance of OPA1 mutations in dominant optic atrophy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Cytoplasmic dynein regulates the subcellular distribution of mitochondria by controlling the recruitment of the fission factor dynamin-related protein-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

The machinery of mitochondrial inheritance and behavior

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Mammalian dynamin-like protein DLP1 tubulates membranes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Mitochondrial fission in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Regulation of mitochondrial fission and apoptosis by the mitochondrial outer membrane protein hFis1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Three-dimensional reconstruction of dynamin in the constricted state

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209605

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209605

1 reference

14 August 2017

1 reference

PubMed ID

16892085