(Q36559630)

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Intratumoral heterogeneity for expression of tyrosine kinase growth factor receptors in human colon cancer surgical specimens and orthotopic tumors.

scientific article published on 17 January 2008

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1 January 2020

Intratumoral heterogeneity for expression of tyrosine kinase growth factor receptors in human colon cancer surgical specimens and orthotopic tumors (English)

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1 January 2020

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1 January 2020

Yasuhiko Kitadai

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Yasuhiko Kitadai

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1 January 2020

Isaiah J. Fidler

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Isaiah J Fidler

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1 January 2020

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Toru Nakamura

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1 January 2020

Sun-Jin Kim

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1 January 2020

Takamitsu Sasaki

4

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1 January 2020

Robert R Langley

6

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1 January 2020

Dominic Fan

7

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1 January 2020

Stanley R Hamilton

8

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1 January 2020

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17 January 2008

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1 January 2020

The American Journal of Pathology

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1 January 2020

172

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1 January 2020

2

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1 January 2020

358-366

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1 January 2020

The role of the organ microenvironment in the biology and therapy of cancer metastasis

1 reference

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Expression of activated platelet-derived growth factor receptor in stromal cells of human colon carcinomas is associated with metastatic potential.

1 reference

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Simultaneous inhibition of EGFR, VEGFR, and platelet-derived growth factor receptor signaling combined with gemcitabine produces therapy of human pancreatic carcinoma and prolongs survival in an orthotopic nude mouse model.

1 reference

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30 September 2017

Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer)

1 reference

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30 September 2017

Induction of apoptosis in tumor-associated endothelial cells and therapy of orthotopic human pancreatic carcinoma in nude mice

1 reference

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Modulation of bone microenvironment with zoledronate enhances the therapeutic effects of STI571 and paclitaxel against experimental bone metastasis of human prostate cancer

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Phase I clinical and pharmacokinetic study of the Novel Raf kinase and vascular endothelial growth factor receptor inhibitor BAY 43-9006 in patients with advanced refractory solid tumors.

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PDGF receptors-mediators of autocrine tumor growth and regulators of tumor vasculature and stroma

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Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

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30 September 2017

Antitumor activity of ZD6474, a vascular endothelial growth factor receptor tyrosine kinase inhibitor, in human cancer cells with acquired resistance to antiepidermal growth factor receptor therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2312354

30 September 2017

The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited

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30 September 2017

Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors

1 reference

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30 September 2017

Expression of hypoxia-inducible factor-1alpha is associated with tumor vascularization in human colorectal carcinoma.

1 reference

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30 September 2017

Effects of blocking platelet-derived growth factor-receptor signaling in a mouse model of experimental prostate cancer bone metastases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2312354

30 September 2017

The organ microenvironment and cancer metastasis

1 reference

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30 September 2017

Critical determinants of metastasis

1 reference

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30 September 2017

The microenvironment of the tumour-host interface

1 reference

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Clinical applications of angiogenic growth factors and their inhibitors

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30 September 2017

Prognostic significance of angiogenesis in human pancreatic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2312354

30 September 2017

Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2312354

30 September 2017

The biology of vascular endothelial growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2312354

30 September 2017

Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2312354

30 September 2017

Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2312354

30 September 2017

Modulation of the organ microenvironment for treatment of cancer metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2312354

30 September 2017

Growth factor receptor tyrosine kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2312354

30 September 2017

Vascular endothelial growth factor is a secreted angiogenic mitogen

1 reference

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30 September 2017

Signal transduction by receptors with tyrosine kinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2312354

30 September 2017

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Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2312354

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In vivo selection of highly metastatic cells from surgical specimens of different primary human colon carcinomas implanted into nude mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2312354

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Critical factors in the biology of human cancer metastasis: twenty-eighth G.H.A. Clowes memorial award lecture

1 reference

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28 June 2018

Platelet-Derived Growth Factor is AngiogenicIn Vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2312354

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2312354

21 September 2018

Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancer: a cohort study

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1 reference

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1 reference

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21 September 2018

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptor content in human renal cell carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/18202197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial growth factor and its correlation with angiogenesis and p53 expression in prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18202197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiogenic heterogeneity: regulation of neoplastic angiogenesis by the organ microenvironment

1 reference

https://pubmed.ncbi.nlm.nih.gov/18202197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic value of vascular endothelial growth factor and its receptor Flt-1 in squamous cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/18202197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor family and renal cell carcinoma: expression and prognostic impact

1 reference

https://pubmed.ncbi.nlm.nih.gov/18202197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptor expression is associated with rapid tumor cell proliferation in renal cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/18202197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptor and transforming growth factor alpha expression in papillary and nonpapillary renal cell carcinoma: correlation with metastatic behavior and prognosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18202197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapy of multidrug resistant human prostate tumors in the prostate of nude mice by simultaneous targeting of the epidermal growth factor receptor and vascular endothelial growth factor receptor on tumor-associated endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18202197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2353/AJPATH.2008.070625

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18202197%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18202197%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18202197%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

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