(Q36571008)

15 August 2017

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title

Regulation of the p14ARF-Mdm2-p53 pathway: an overview in breast cancer (English)

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15 August 2017

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Anshu Agrawal

1

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15 August 2017

Jianhui Yang

series ordinal

2

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15 August 2017

Richard F Murphy

series ordinal

3

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15 August 2017

Devendra K Agrawal

series ordinal

4

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15 August 2017

17 August 2006

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Experimental and Molecular Pathology

15 August 2017

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15 August 2017

81

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15 August 2017

115-122

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15 August 2017

2

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Relationship between the expression of various markers and prognostic factors in breast cancer

15 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Molecular and cellular analysis of basement membrane invasion by human breast cancer cells in Matrigel-based in vitro assays

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Centrosome hyperamplification in human cancer: chromosome instability induced by p53 mutation and/or Mdm2 overexpression.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Activation of p53 by MDM2 antagonists can protect proliferating cells from mitotic inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Inhibiting the p53-MDM2 interaction: an important target for cancer therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Prognostic and predictive factors in early-stage breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

p53 mutation as a genetic trait of typical medullary breast carcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Detection of a transformation-related antigen in chemically induced sarcomas and other transformed cells of the mouse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Understanding breast cancer risk -- where do we stand in 2005?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Cell cycle checkpoints and their impact on anticancer therapeutic strategies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Regulators of apoptosis in human breast cancer

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Turning p53 on or off: either way may treat cancer

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Functions of the MDM2 oncoprotein

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Signaling pathways and intracellular targets of sulforaphane mediating cell cycle arrest and apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Caveolin-1 expression negatively regulates cell cycle progression by inducing G(0)/G(1) arrest via a p53/p21(WAF1/Cip1)-dependent mechanism.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

The p53 pathway in breast cancer

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Geminin predicts adverse clinical outcome in breast cancer by reflecting cell-cycle progression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

7 January 2021

Cancer statistics, 2001

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Assessing p53 in clinical contexts: unlearned lessons and new perspectives

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Database of p53 gene somatic mutations in human tumors and cell lines: updated compilation and future prospects

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Combined analysis of p53 and RB pathways in epithelial ovarian cancer.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Alteration of cell cycle regulators correlates with survival in epithelial ovarian cancer patients.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

BRCA1 in cancer, cell cycle and genomic stability

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

p21/waf1/cip1 and mdm-2 expression in breast carcinoma patients as related to prognosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Apigenin inhibits VEGF and HIF-1 expression via PI3K/AKT/p70S6K1 and HDM2/p53 pathways.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Oncogenic pathways in hereditary and sporadic breast cancer

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Prognostic significance of apoptosis regulators in breast cancer.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Oncogenic ras activates the ARF-p53 pathway to suppress epithelial cell transformation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Apigenin acts on the tumor cell invasion process and regulates protease production

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

p14ARF homozygous deletion or MDM2 overexpression in Burkitt lymphoma lines carrying wild type p53

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Gankyrin: an intriguing name for a novel regulator of p53 and RB.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

7 January 2021

The heart of the cycle

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Maspin--a novel protease inhibitor with tumor-suppressing activity in breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Increase in wild-type p53 stability and transactivational activity by the chemopreventive agent apigenin in keratinocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Twist is a potential oncogene that inhibits apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Role of the proto-oncogene Pokemon in cellular transformation and ARF repression

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

The transcription factor Pokemon: a new key player in cancer pathogenesis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Expression of the transcription factors snail, slug, and twist and their clinical significance in human breast cancer

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Amplification of the MDM2 gene in human breast cancer and its association with MDM2 and p53 protein status.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Geminin, an inhibitor of DNA replication, is degraded during mitosis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Global breast cancer mortality statistics

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Twist overexpression induces in vivo angiogenesis and correlates with chromosomal instability in breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Disrupting the p53-mdm2 interaction as a potential therapeutic modality.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Increased expression of geminin stimulates the growth of mammary epithelial cells and is a frequent event in human tumors

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Principles of CDK regulation

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Molecular structure of human geminin

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Amplification of a gene encoding a p53-associated protein in human sarcomas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Disruption of PLZP in mice leads to increased T-lymphocyte proliferation, cytokine production, and altered hematopoietic stem cell homeostasis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Correlations of cell cycle regulators (p53, p21, pRb and mdm2) and c-erbB-2 with biological markers of proliferation and overall survival in breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Clinicopathological significance and survival influence of p53 protein expression in gastric carcinoma.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

A twist for survival and cancer progression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

MDM2 gene amplification in human breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Compromised HOXA5 function can limit p53 expression in human breast tumours

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Pokemon expression in malignant glioma: an application of bioinformatics methods

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

ASPP proteins specifically stimulate the apoptotic function of p53

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Cell signaling pathways altered by natural chemopreventive agents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Stimulatory effect of genistein and apigenin on the growth of breast cancer cells correlates with their ability to activate ER alpha

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Cancer in women: prevention and early detection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Role of the INK4a locus in tumor suppression and cell mortality.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

INK4a/ARF: a multifunctional tumor suppressor locus

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Tumor surveillance via the ARF-p53 pathway.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

The RB and p53 pathways in cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

DNA replication licensing and cell cycle kinetics of normal and neoplastic breast

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Concomitant expression of p16INK4a and p14ARF in primary breast cancer and analysis of inactivation mechanisms.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Pokémon blocks gene name.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

p53-independent role of MDM2 in TGF-beta1 resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Recent developments in critical genes in the molecular biology of breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Geminin Regulates Multiple Steps of the Chromosome Inheritance Cycle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Sumoylation induced by the Arf tumor suppressor: a p53-independent function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Breast cancer progression with a Twist

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Small-molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: implications for therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Targeted therapies in breast cancer.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

p14ARF expression in invasive breast cancers and ductal carcinoma in situ--relationships to p53 and Hdm2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

7 January 2021

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Live or let die: the cell's response to p53

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Phytoestrogen concentration determines effects on DNA synthesis in human breast cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Nucleolar Arf sequesters Mdm2 and activates p53

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

p53-independent functions of the p19(ARF) tumor suppressor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Human p14(ARF)-mediated cell cycle arrest strictly depends on intact p53 signaling pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

mdm2: a bridge over the two tumour suppressors, p53 and Rb.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

The destruction box of human Geminin is critical for proliferation and tumor growth in human colon cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Apigenin induced apoptosis through p53-dependent pathway in human cervical carcinoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

Rereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpoint

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2006.07.001

10.1016/J.YEXMP.2006.07.001

7 January 2021

Identifiers

DOI

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15 August 2017

1 reference