(Q36571177)

English

Cryo-EM structure of the DNA-dependent protein kinase catalytic subunit at subnanometer resolution reveals alpha helices and insight into DNA binding

scientific article published on March 2008

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scholarly article

1 reference

Europe PubMed Central

15 August 2017

Cryo-EM structure of the DNA-dependent protein kinase catalytic subunit at subnanometer resolution reveals alpha helices and insight into DNA binding (English)

1 reference

Europe PubMed Central

15 August 2017

cryogenic electron microscopy

0 references

author name string

Dewight R Williams

1

1 reference

Europe PubMed Central

15 August 2017

Kyung-Jong Lee

2

1 reference

Europe PubMed Central

15 August 2017

Jian Shi

3

1 reference

Europe PubMed Central

15 August 2017

David J Chen

4

1 reference

Europe PubMed Central

15 August 2017

Phoebe L Stewart

5

1 reference

Europe PubMed Central

15 August 2017

publication date

1 March 2008

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

16

1 reference

Europe PubMed Central

15 August 2017

468-477

1 reference

Europe PubMed Central

15 August 2017

3

1 reference

Europe PubMed Central

15 August 2017

Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks

1 reference

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1 reference

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Ab initio resolution measurement for single particle structures

1 reference

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Visualization of alpha-helices in a 6-angstrom resolution cryoelectron microscopy structure of adenovirus allows refinement of capsid protein assignments

1 reference

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DNA-PKcs dependence of Artemis endonucleolytic activity, differences between hairpins and 5' or 3' overhangs

1 reference

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Role of non-homologous end joining (NHEJ) in maintaining genomic integrity

1 reference

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Terminal DNA structure and ATP influence binding parameters of the DNA-dependent protein kinase at an early step prior to DNA synapsis

1 reference

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XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining

1 reference

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Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly

1 reference

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Autophosphorylation of DNA-dependent protein kinase regulates DNA end processing and may also alter double-strand break repair pathway choice

1 reference

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Electron cryomicroscopy of single particles at subnanometer resolution

1 reference

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The DNA-dependent protein kinase catalytic subunit phosphorylation sites in human Artemis

1 reference

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The HHpred interactive server for protein homology detection and structure prediction

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Cell cycle dependence of DNA-dependent protein kinase phosphorylation in response to DNA double strand breaks.

1 reference

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Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the multisubunit cullin-dependent ubiquitin ligases

1 reference

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30 September 2017

The mechanism of non-homologous end-joining: a synopsis of synapsis

1 reference

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PI 3-kinase related kinases: 'big' players in stress-induced signaling pathways

1 reference

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UCSF Chimera--a visualization system for exploratory research and analysis

1 reference

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Initiating cellular stress responses

1 reference

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The DNA-dependent protein kinase: the director at the end.

1 reference

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30 September 2017

The role of DNA dependent protein kinase in synapsis of DNA ends.

1 reference

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30 September 2017

Visualization of DNA-induced conformational changes in the DNA repair kinase DNA-PKcs

1 reference

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Human severe combined immune deficiency and DNA repair

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Optimal determination of particle orientation, absolute hand, and contrast loss in single-particle electron cryomicroscopy

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323513

30 September 2017

https://pubmed.ncbi.nlm.nih.gov/18334221

12 December 2020

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Determination of icosahedral virus structures by electron cryomicroscopy at subnanometer resolution

1 reference

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30 September 2017

Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323513

30 September 2017

Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323513

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Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase

1 reference

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30 September 2017

Synapsis of DNA ends by DNA-dependent protein kinase

1 reference

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V(D)J recombination: RAG proteins, repair factors, and regulation

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Structural Determinants of Phosphoinositide 3-Kinase Inhibition by Wortmannin, LY294002, Quercetin, Myricetin, and Staurosporine

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Geometry of a complex formed by double strand break repair proteins at a single DNA end: recruitment of DNA-PKcs induces inward translocation of Ku protein

1 reference

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Productive and nonproductive complexes of Ku and DNA-dependent protein kinase at DNA termini

1 reference

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Binding of Ku and c-Abl at the kinase homology region of DNA-dependent protein kinase catalytic subunit

1 reference

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Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae

1 reference

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The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen

1 reference

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DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

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Structure of DNA-dependent protein kinase: implications for its regulation by DNA.

1 reference

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Processing of DNA for nonhomologous end-joining is controlled by kinase activity and XRCC4/ligase IV.

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Three-dimensional structure and regulation of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs).

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The ATRs, ATMs, and TORs are giant HEAT repeat proteins.

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Cryo-EM imaging of the catalytic subunit of the DNA-dependent protein kinase

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https://pubmed.ncbi.nlm.nih.gov/18334221

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Identifiers

10.1016/J.STR.2007.12.014

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

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